Advantage Plus II
100/100
This product looks safe
- No ingredients exceed tolerable upper intake levels
- 38% of ingredients have research evidence
A
Label Compliance Grade
Product Label
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Label Data
1 Capsule(s)
Serving Size
50
Servings
Other Combinations
Product Type
38%
Evidence Coverage
Supplement Facts — Evidence Check
10 mg
(50% DV)
✅ Within RDA (0.7× RDA of 14 mg)
📚 193 studies (Tier A: 5, B: 63)
10 mg
(500% DV)
📊 7.7× RDA — above typical dose (UL: 100 mg)
📚 113 studies (Tier A: 3, B: 35)
Lecithin
400 mg
Polysaccharides
300 mg
Mucopolysaccharides
100 mg
EDTA
100 mg
50 mg
✅ Within RDA (0.1× RDA of 550 mg)
📚 36 studies (Tier A: 1, B: 7)
Papain
50 mg
Other Ingredients
Gelatin
Cellulose
Silicon Dioxide
Vegetable Stearate
Label Claims — Verification
❓
All Other
All Other (97% of products)
Structure/Function (86% of products)
Nutrient (36% of products)
Target Groups
Adult (18 - 50 Years)
Dairy Free
Sugar Free
Product Information
📋 Directions for Use
Suggested Usage: As a dietary supplement, adults take 1 to 2 capsules daily or as directed by your healthcare professional.
⚠️ Warnings & Precautions
KEEP OUT OF REACH OF CHILDREN.
Tamper resistant package, do not use if outer seal is missing.
🧪 Formulation Notes
This product contains NO yeast, wheat gluten, milk/dairy, corn, sodium, sugar, starch, artificial coloring, preservatives or flavoring.
Additional Information
For optimal storage conditions, store in a cool, dry place. (59(0)-77(0)F/15(0)-25(0)C) (35-65% relative humidity)
Formula #7475
Product Details
UPC / SKU
3 10539 00338 1
DSLD Entry Date
2012-06-01
Product Type
Other Combinations
Form
Capsule
Brand
Douglas Laboratories
DSLD ID
8772
Data Updated
2026-04-11
Research Evidence
241
Research Sources
55
Avg Quality Score
113
Meta Analysis
75
Systematic Review
32
Rct
11
Clinical Trial
3
Other
3
Regulatory Source
1
Cochrane Review
1
Narrative Review
1
Openfda Safety
A
Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
A
Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
A
A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
A
Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
B
Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
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