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Niacinamide

product on market Tablet or Pill GNC Women's Ultra Mega Safety: 60/100
60/100

Review before taking

  • Niacin: 100mg is 2.9× the Tolerable Upper Intake Level (35mg)
  • 100% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Niacin supports cellular energy production and may improve lipid profiles, though research evidence for this specific formulation is limited. Due to a safety score of 60, users should be aware of potential side effects such as skin flushing. Consult a professional regarding appropriate dosage levels.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 100mg is 2.9× the Tolerable Upper Intake Level (35mg)

AI-generated · Qwen 3.6 · grounded in 2 sources · methodology

This product received a low safety score because it contains 100mg of Niacin, which is nearly three times the recommended upper limit for daily intake.

Label

Product Label

Label for Niacinamide
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Round White Tablet(s)
Serving Size
Vitamin
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

100 mg (500% DV)
Exceeds UL by 2.9× (UL: 35 mg) 196 studies (A:5, B:63)

Other Ingredients

Dicalcium Phosphate Cellulose whole Brown Rice
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: As a dietary supplement, take the contents of one pack daily with food.

To ensure a complete nutritional program, take daily with these GNC products: ~ Ultra Probiotic Complex ~ SuperFoods Supreme ~ Ultra Omega Krill Oil ~ Natural Brand Clear Mixing Super Fiber

Warnings & Precautions

Keep out of reach of children.

Warning: Consult your physician prior to using this product if you are pregnant, nursing, taking medication, or have a medical condition.

Discontinue use two weeks prior to surgery.

Formulation Notes

No artificial colors, no artificial flavors, no wheat, no gluten, no dairy, yeast free.

GNC Women's Ultra Mega Heart Vitapak Program conveniently combines nutrients that support a woman's overall nutritional needs with focused ingredients to promote heart health and may reduce the risk of heart disease.

Additional Information

CODE 329611 APG

Conforms to USP <2091> for weight. Meets USP <2040> disintegration.

Actual size

Store in a cool, dry place.

GNC Quality Commitment For more than 79 years, GNC has been the leader in the development of superior nutritional supplements. Our products are produced using only fresh, high-quality ingredients and are manufactured under the strictest quality controls. GNC Guarantee If you are not 100% completely satisfied, return the unused portion of the product with your receipt to a GNC store within 30 days. Our trained sales staff will either refund your purchase price or, if you prefer, assist you in finding a replacement product to help you Live Well.

Physician Endorsed

Niacinamide Provides dietary support for a healthy blood lipid profile, and plays an important function in energy metabolism.

In a randomized, double-blind, placebo-controlled study of 112 healthy volunteers, subjects taking the GNC vitamin and mineral blend in this product for six weeks experienced statistically significant improvements in markers of B vitamin and antioxidant status, as well as improvements in SF-36 Vitality and Mental Health scores compared to those taking a placebo.

This product is endorsed by the GNC Medical Advisory Board. This team of esteemed physicians utilizes their extensive medical knowledge and experience to aid in the creation of GNC premium products, helping you to achieve optimal health through comprehensive nutritional support so you can live your best life!

Metadata

Product Details

DSLD Entry Date2018-02-23
Product TypeVitamin
FormTablet or Pill
DSLD ID83096
Data Updated2026-04-11
Research

Research Evidence

241
Research Sources
55
Avg Quality
113
Meta Analysis
75
Systematic Review
32
Rct
11
Clinical Trial
3
Other
3
Regulatory Source
1
Cochrane Review
1
Narrative Review
1
Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013 PubMed DOI
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014 PubMed DOI
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024 PubMed DOI
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010 PubMed DOI
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010 PubMed DOI
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019 PubMed DOI
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016 PubMed DOI
View all evidence for Niacin →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.