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Niacin 500 mg

product on market Tablet or Pill Country Life Safety: 87/100
87/100

This product is generally safe

  • Niacin: 500mg is 14.3× the Tolerable Upper Intake Level (35mg)
  • 67% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

Niacin is supported by strong evidence for managing lipid levels, while calcium and magnesium support bone health and neuromuscular function. Research indicates these ingredients are generally well-tolerated, though evidence coverage for this specific formulation is limited. The profile maintains a high safety score.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 500mg is 14.3× the Tolerable Upper Intake Level (35mg)

Label

Product Label

Label for Niacin 500 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Tablet(s)
Serving Size
Other Combinations
Product Type
67%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

500 mg (2500% DV)
Exceeds UL by 14.3× (UL: 35 mg) 196 studies (A:5, B:63)
Calcium
36 mg (4% DV)
30 mg (8% DV)
Within RDA (0.1× RDA) 316 studies (A:8, B:159)

Other Ingredients

Cellulose Magnesium Stearate Cellulose & Glycerin Coating Stearic Acid Silica Maltodextrin Vegetable Glaze
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: Adults take one (1) tablet immediately following a meal.

Warnings & Precautions

Do not exceed recommended dose.

As a reminder, discuss the supplements and medications that you take with your health care providers.

Caution: If you are pregnant, nursing, or taking medication, have a medical condition or planning surgery, consult a doctor before using this product.

Stop using and consult a doctor if any adverse reactions occur. Notice: Use of this product may cause skin flushing, burning, itching, or rash. Do not take on an empty stomach.

Caution: Follow label directions. Do not take more than 500 mg of Niacin per day or switch to more than 250 mg of sustained release Niacin per day, except under supervision of a physician. Do not accept if seal is broken.

Keep out of the reach of children.

Formulation Notes

Yes Certified gluten-free by GFCO.org

Yes Certified vegan by the AVA

Yes Kosher-Parve

Yes Certified Halal by IFANCA

No Yeast, wheat or soy No Milk, salt or sugar No Preservatives No Artificial colors, flavors or sweeteners No GMOs

Certified Gluten-free

Additional Information

Niacin (Vitamin B3) is required for the metabolism of carbohydrates and protein into energy. Niacin also supports cardiovascular and nervous system health.

Yes Recyclable packaging Yes Manufacturing supports wind power

This product has been manufactured at a GMP registered facility.

Product No. 6585 08I17NL

K Parve

IFANCA Certified M Halal

Certified Circle B Corporation

Established 1971

Supports energy Helps support cardiovascular health Supports healthy nervous system

Our pledge of integrity Authenticity Cleanliness Freshness Consistency Accuracy

Store in a dry place between 59(0)-86(0) F.

Metadata

Product Details

UPC / SKU0 15794 06585 2
DSLD Entry Date2018-01-25
Product TypeOther Combinations
FormTablet or Pill
BrandCountry Life
DSLD ID81178
Data Updated2026-04-11
Research

Research Evidence

241
Research Sources
55
Avg Quality
113
Meta Analysis
75
Systematic Review
32
Rct
11
Clinical Trial
3
Other
3
Regulatory Source
1
Cochrane Review
1
Narrative Review
1
Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013 PubMed DOI
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014 PubMed DOI
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024 PubMed DOI
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010 PubMed DOI
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010 PubMed DOI
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019 PubMed DOI
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016 PubMed DOI
View all evidence for Niacin →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.