5-HTP 100 mg

product on market Capsule Highland Laboratories 🟢 Safety: 100/100
Brand: Highland Laboratories
🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

1 Vegetarian Capsule(s) Serving Size
Botanical with Nutrients Product Type
100% Evidence Coverage

Supplement Facts — Evidence Check

5 mg (25% DV)
✅ Within RDA (0.4× RDA of 14 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 5mg UL 35mg
10 mg (500% DV)
📊 7.7× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 10mg UL 100mg
100 mg
📊 Market median: 100.0mg (116 products) 📚 15 studies (Tier A: 0, B: 3)
This product: 100mg

Other Ingredients

Enhance Vegetable Cellulose Calcium Phosphate Cellulose Magnesium Trisilicate Silica Magnesium Stearate

Label Claims — Verification

❓ All Other
All Other (99% of products) Structure/Function (78% of products) Nutrient (52% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free Dairy Free Sugar Free

Product Information

📋 Directions for Use

One capsule daily, as a dietary supplement.

🧪 Formulation Notes

No soy, salt, yeast, gluten, milk & egg products, sugar, starch, or preservatives

Formulated with Enhance metabolite uptake enhancers. Contains citrus products.

Additional Information

Serotonin support

GMP Quality Assured Earth Friendly

% Daily Value

Enzyme co-factors B-6 and niacin are associated with serotonin production.

PR 1390

Product Details

UPC / SKU 7 68305 13903 9
DSLD Entry Date 2017-10-21
Product Type Botanical with Nutrients
Form Capsule
Brand Highland Laboratories
DSLD ID 79999
Data Updated 2026-04-11

Research Evidence

21 Research Sources
53 Avg Quality Score
11 Systematic Review
6 Rct
4 Meta Analysis
B Combination pharmacotherapy for the treatment of fibromyalgia in adults
Systematic Review The Cochrane database of systematic reviews 2018
PubMed DOI
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2001
PubMed Cochrane
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2002
PubMed Cochrane
B The impact of 5-hydroxytryptophan supplementation on sleep quality and gut microbiota composition in older adults: A randomized controlled trial
Rct Clinical nutrition (Edinburgh, Scotland) 2024
PubMed DOI
B The Impact of 5-Hydroxytryptophan Supplementation on Cognitive Function and Mood in Singapore Older Adults: A Randomized Controlled Trial
Rct Nutrients 2025
PubMed DOI
B The Efficacy of Different Triptans for the Treatment of Acute Headache in Pediatric Migraine: A Systematic Review
Systematic Review Indian pediatrics 2023
PubMed
B The effect of therapeutic massage combined with conventional therapy in children with functional dyspepsia: a systematic review and meta-analysis
Systematic Review Frontiers in pharmacology 2025
PubMed DOI
C Sleep disorders in children
Systematic Review BMJ clinical evidence 2010
PubMed
C Effects of 5-hydroxytryptophan on distinct types of depression: a systematic review and meta-analysis
Meta Analysis Nutrition reviews 2020
PubMed DOI
C Investigating genetic links between biological aging and adverse pregnancy outcomes
Meta Analysis Biogerontology 2025
PubMed DOI
View all evidence for 5 Htp →

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