Home/ Supplements/ 5 Htp/ 5-HTP 100 mg

5-HTP 100 mg

product on market Capsule Highland Laboratories Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · grounded in 1 source · methodology

5-HTP is supported by moderate evidence for supporting mood and sleep by increasing serotonin levels. Vitamin B6 and Niacin act as essential cofactors in neurotransmitter synthesis and metabolic function. Overall, these ingredients are well-researched for their roles in neurological and systemic health.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for 5-HTP 100 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Vegetarian Capsule(s)
Serving Size
Botanical with Nutrients
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

5 mg (25% DV)
Within RDA (0.4× RDA) 196 studies (A:5, B:63)
10 mg (500% DV)
7.7× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
100 mg
Market median: 100.0mg (116 products) 18 studies (A:0, B:3)

Other Ingredients

Enhance Vegetable Cellulose Calcium Phosphate Cellulose Magnesium Trisilicate Silica Magnesium Stearate
Claims

Label Claims — Verification

Unverified All Other
Info

Product Information

Directions for Use

One capsule daily, as a dietary supplement.

Formulation Notes

No soy, salt, yeast, gluten, milk & egg products, sugar, starch, or preservatives

Formulated with Enhance metabolite uptake enhancers. Contains citrus products.

Additional Information

Serotonin support

GMP Quality Assured Earth Friendly

% Daily Value

Enzyme co-factors B-6 and niacin are associated with serotonin production.

PR 1390

Metadata

Product Details

UPC / SKU7 68305 13903 9
DSLD Entry Date2017-10-21
Product TypeBotanical with Nutrients
FormCapsule
BrandHighland Laboratories
DSLD ID79999
Data Updated2026-04-11
Research

Research Evidence

21
Research Sources
53
Avg Quality
11
Systematic Review
6
Rct
4
Meta Analysis
B Combination pharmacotherapy for the treatment of fibromyalgia in adults
Systematic Review The Cochrane database of systematic reviews 2018 PubMed DOI
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2001 PubMed
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2002 PubMed
B The impact of 5-hydroxytryptophan supplementation on sleep quality and gut microbiota composition in older adults: A randomized controlled trial
Rct Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
B The Impact of 5-Hydroxytryptophan Supplementation on Cognitive Function and Mood in Singapore Older Adults: A Randomized Controlled Trial
Rct Nutrients 2025 PubMed DOI
B The Efficacy of Different Triptans for the Treatment of Acute Headache in Pediatric Migraine: A Systematic Review
Systematic Review Indian pediatrics 2023 PubMed
B The effect of therapeutic massage combined with conventional therapy in children with functional dyspepsia: a systematic review and meta-analysis
Systematic Review Frontiers in pharmacology 2025 PubMed DOI
C Sleep disorders in children
Systematic Review BMJ clinical evidence 2010 PubMed
C Effects of 5-hydroxytryptophan on distinct types of depression: a systematic review and meta-analysis
Meta Analysis Nutrition reviews 2020 PubMed DOI
C Investigating genetic links between biological aging and adverse pregnancy outcomes
Meta Analysis Biogerontology 2025 PubMed DOI
View all evidence for 5 Htp →
Compare

Similar Products

5-HTP
XYMOGEN · Capsule
100
5-HTP 100 mg
VitaCeutical Labs · Capsule
100
5-HTP 5-Hydroxy-L-Trytophan 50
LifeLink · Capsule
100
5-HTP 5-Hydroxy-L-Trytophan 50
LifeLink · Capsule
100
5-HTP 5-Hydroxy-L-Trytophan 100
LifeLink · Capsule
100
View all 5 Htp products →
5 Htp research Best 5 Htp All 5 Htp products More from Highland Laboratories View on NIH DSLD →

This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.