Melatonin 3 mg by Highland Laboratories — Ingredients, Evidence & Safety

Product Label

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Label Data

1 Vegetarian Tablet(s) Serving Size

Other Combinations Product Type

100% Evidence Coverage

Supplement Facts — Evidence Check

Niacin

5 mg (25% DV)

✅ Within RDA (0.4× RDA of 14 mg) 📚 193 studies (Tier A: 5, B: 63)

RDA 14mg This product: 5mg UL 35mg

Vitamin B6

5 mg (250% DV)

📊 3.8× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)

RDA 1.3mg This product: 5mg UL 100mg

Melatonin, Crystalline, Pure

3 mg

📊 Market median: 3.0mg (984 products) 📚 236 studies (Tier A: 2, B: 109)

This product: 3mg UL 10mg

Other Ingredients

Calcium Phosphate Enhance Cellulose Silica Vegetable Stearate Magnesium Stearate

Label Claims — Verification

❓ All Other

All Other (100% of products) Structure/Function (86% of products) Nutrient (7% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free Dairy Free Sugar Free

Product Information

📋 Directions for Use

One to two tablets at night on an empty stomach, as a dietary supplement.

⚠️ Warnings & Precautions

Individuals under 18 years old, under a physician's care, or pregnant and lactating women, or those considering pregnancy, should consult their health care practitioner before using.

🧪 Formulation Notes

No soy, salt, yeast, gluten, milk & egg products, sugar, starch, or preservatives.

Formulated with Enhance metabolite uptake enhancers. Contains citrus products.

Additional Information

Also available in 120 count

GMP Quality Assured Earth Friendly

% Daily Value

PR 1352

Product Details

UPC / SKU 7 68305 13526 0

DSLD Entry Date 2017-12-22

Product Type Other Combinations

Form Tablet or Pill

Brand Highland Laboratories

DSLD ID 79981

Data Updated 2026-04-11

Research Evidence

291 Research Sources

55 Avg Quality Score

129 Meta Analysis

93 Systematic Review

51 Rct

11 Clinical Trial

2 Other

2 Regulatory Source

1 Openfda Safety

A Interventions for preventing delirium in hospitalised non-ICU patients

Meta Analysis The Cochrane database of systematic reviews 2016

PubMed DOI

A Melatonin for preoperative and postoperative anxiety in adults

Meta Analysis The Cochrane database of systematic reviews 2020

PubMed DOI Cochrane

A Effect of melatonin on quality of life and symptoms in patients with cancer: a systematic review and meta-analysis of randomised controlled trials

Meta Analysis BMJ open 2022

PubMed DOI

B Pharmacological interventions for prevention of weight gain in people with schizophrenia

Meta Analysis The Cochrane database of systematic reviews 2022

PubMed DOI

B Melatonin for pre- and postoperative anxiety in adults

Meta Analysis The Cochrane database of systematic reviews 2015

PubMed DOI Cochrane

B Prevention of depression in adults with long-term physical conditions

Meta Analysis The Cochrane database of systematic reviews 2021

PubMed DOI

B Comparative effects of pharmacological interventions for the acute and long-term management of insomnia disorder in adults: a systematic review and network meta-analysis

Systematic Review Lancet (London, England) 2022

PubMed DOI

B Does melatonin administration reduce the incidence of postoperative delirium in adults? Systematic review and meta-analysis

Meta Analysis BMJ open 2023

PubMed DOI

B Second-generation antidepressants for preventing seasonal affective disorder in adults

Meta Analysis The Cochrane database of systematic reviews 2015

PubMed DOI

B Interventions for preventing type 2 diabetes in adults with mental disorders in low- and middle-income countries

Meta Analysis The Cochrane database of systematic reviews 2021

PubMed DOI

View all evidence for Melatonin →