🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

Product Label

📸

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Label Data

2 Capsule(s) Serving Size
60 Servings
Other Combinations Product Type
100% Evidence Coverage

Supplement Facts — Evidence Check

120 mg (22% DV)
✅ Within RDA (0.2× RDA of 550 mg) 📚 36 studies (Tier A: 1, B: 7)
RDA 550mg This product: 120mg UL 3500mg
6 mg
📊 Market median: 108.0mg (8 products) 📚 9 studies (Tier A: 0, B: 4)
This product: 6mg
50 mg
📊 Market median: 550.0mg (217 products) 📚 29 studies (Tier A: 0, B: 5)
This product: 50mg

Other Ingredients

Microcrystalline Cellulose purified Water Capsule Shell

Label Claims — Verification

All Other
Structure/Function
All Other (99% of products) Structure/Function (95% of products) Nutrient (80% of products)

Target Groups

Vegan Vegetarian Seniors/Mature (>50 Years) - Women ONLY Gluten Free Dairy Free Sugar Free

Product Information

📋 Directions for Use

Directions: Take 2 capsules, once daily, with or without food. For optimum results, take with your daily calcium supplement or a calcium rich food source.

⚠️ Warnings & Precautions

Consult your health professional before use if you are pregnant, breastfeeding or trying to conceive, or if you are taking medication, have a medical condition or anticipate a surgery.

Keep out of the reach of children.

Sealed for your protection. Do not use if seal if broken.

🧪 Formulation Notes

Does not contain: Gluten, wheat, soy, yeast, dairy, sugar, starch, egg, fish, shellfish, peanuts or tree nuts, animal products, GMOs or artificial colors, preservatives or sweeteners.

V Vegan Vegetarian

Specially formulated for women 50 plus

ch-OSA Original formula

The ch-OSA in Collagenizer 50 Plus generates collagen. The inositol helps maintain "osteo-balance."

Osteo-balance is vital for women over 50 as bone-destroying osteoclasts begin to outpace bone-building osteoblasts.

Suitable for vegetarians/vegans.

Additional Information

V Vegan Vegetarian

Measured at the hip

Clinically proven

Increases bone collagen formation Increases calcium binding sites Promotes bone pliability Increases bone mineral density (BMD) Boosts the effectiveness of dietary and supplement calcium Helps maintain positive osteoblast balance

Store in a cool dry place.

Made in Belgium

R1

The science of healthy bones at 50 plus The National Institutes of Health reports that it takes both calcium and collagen to build strong healthy bones. Collagen serves as the "binding sites" for calcium and gives bone the pliability it needs to withstand physical stress.

Insufficient bone collagen Insufficient calcium "binding sets," low BMD brittle bone and "holes" in bone (osteoporosis) Optimal bone collagen Optimal calcium "binding sets," optimum BMD, strong, pliable with ability to bend-not-break

isura Non-GMO - Mass spec Documentation - Lab tested

Now in new small caps

Product facts

Clinical trial results

Increase in bone collagen formulation % change in serum P1NP Level (ug/l) 33 35 37 39 41 43 Calcium & vitamin D ch-OSA calcium & vitamin D 36.49 42.04 15.0% increase in P1NP first 12 months

Increase in BMD at hip Change in bone mineral density -1.00 -50 0 .50 1.00 Calcium & vitamin D -1.22 ch-OSA calcium & vitamin D +.78 2.0% improvement in BMD at hip first 12 months

Product Details

UPC / SKU 5 425010 39155 2
DSLD Entry Date 2017-09-21
Product Type Other Combinations
Form Capsule
Brand BioSil
DSLD ID 77034
Data Updated 2026-04-11

Research Evidence

281 Research Sources
54 Avg Quality Score
141 Meta Analysis
72 Systematic Review
45 Rct
18 Clinical Trial
2 Narrative Review
1 Other
1 Guideline
1 Openfda Safety
A Vascular closure devices for femoral arterial puncture site haemostasis
Meta Analysis The Cochrane database of systematic reviews 2016
B Effects of Oral Collagen for Skin Anti-Aging: A Systematic Review and Meta-Analysis
Meta Analysis Nutrients 2023
B Transepithelial versus epithelium-off corneal crosslinking for progressive keratoconus
Meta Analysis The Cochrane database of systematic reviews 2021
B Bisphosphonate therapy for osteogenesis imperfecta
Meta Analysis The Cochrane database of systematic reviews 2014
B Punctal occlusion for dry eye syndrome
Meta Analysis The Cochrane database of systematic reviews 2017
B Dressings and topical agents containing hyaluronic acid for chronic wound healing
Systematic Review The Cochrane database of systematic reviews 2023
B Efficacy of statins for osteoporosis: a systematic review and meta-analysis
Meta Analysis Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 2017
B Drugs to reduce bleeding and transfusion in major open vascular or endovascular surgery: a systematic review and network meta-analysis
Systematic Review The Cochrane database of systematic reviews 2023
B Bisphosphonate therapy for osteogenesis imperfecta
Meta Analysis The Cochrane database of systematic reviews 2008
B Bisphosphonates for osteoporosis in primary biliary cirrhosis
Meta Analysis The Cochrane database of systematic reviews 2011
View all evidence for Collagen →

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