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Bone Collagenizer 50 Plus

product on market Capsule BioSil Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Silicon and inositol are studied for their roles in supporting connective tissue and cellular signaling, while choline supports cognitive function. However, the available evidence coverage for this specific ingredient combination is limited. These components are generally considered safe for consumption.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Bone Collagenizer 50 Plus
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Capsule(s)
Serving Size
60
Servings
Other Combinations
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

120 mg (22% DV)
Within RDA (0.2× RDA) 38 studies (A:1, B:7)
6 mg
Market median: 108.0mg (8 products) 9 studies (A:0, B:4)
50 mg
Market median: 550.0mg (217 products) 29 studies (A:0, B:5)

Other Ingredients

Microcrystalline Cellulose purified Water Capsule Shell
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: Take 2 capsules, once daily, with or without food. For optimum results, take with your daily calcium supplement or a calcium rich food source.

Warnings & Precautions

Consult your health professional before use if you are pregnant, breastfeeding or trying to conceive, or if you are taking medication, have a medical condition or anticipate a surgery.

Keep out of the reach of children.

Sealed for your protection. Do not use if seal if broken.

Formulation Notes

Does not contain: Gluten, wheat, soy, yeast, dairy, sugar, starch, egg, fish, shellfish, peanuts or tree nuts, animal products, GMOs or artificial colors, preservatives or sweeteners.

V Vegan Vegetarian

Specially formulated for women 50 plus

ch-OSA Original formula

The ch-OSA in Collagenizer 50 Plus generates collagen. The inositol helps maintain "osteo-balance."

Osteo-balance is vital for women over 50 as bone-destroying osteoclasts begin to outpace bone-building osteoblasts.

Suitable for vegetarians/vegans.

Additional Information

V Vegan Vegetarian

Measured at the hip

Clinically proven

Increases bone collagen formation Increases calcium binding sites Promotes bone pliability Increases bone mineral density (BMD) Boosts the effectiveness of dietary and supplement calcium Helps maintain positive osteoblast balance

Store in a cool dry place.

Made in Belgium

R1

The science of healthy bones at 50 plus The National Institutes of Health reports that it takes both calcium and collagen to build strong healthy bones. Collagen serves as the "binding sites" for calcium and gives bone the pliability it needs to withstand physical stress.

Insufficient bone collagen Insufficient calcium "binding sets," low BMD brittle bone and "holes" in bone (osteoporosis) Optimal bone collagen Optimal calcium "binding sets," optimum BMD, strong, pliable with ability to bend-not-break

isura Non-GMO - Mass spec Documentation - Lab tested

Now in new small caps

Product facts

Clinical trial results

Increase in bone collagen formulation % change in serum P1NP Level (ug/l) 33 35 37 39 41 43 Calcium & vitamin D ch-OSA calcium & vitamin D 36.49 42.04 15.0% increase in P1NP first 12 months

Increase in BMD at hip Change in bone mineral density -1.00 -50 0 .50 1.00 Calcium & vitamin D -1.22 ch-OSA calcium & vitamin D +.78 2.0% improvement in BMD at hip first 12 months

Metadata

Product Details

UPC / SKU5 425010 39155 2
DSLD Entry Date2017-09-21
Product TypeOther Combinations
FormCapsule
BrandBioSil
DSLD ID77034
Data Updated2026-04-11
Research

Research Evidence

281
Research Sources
54
Avg Quality
141
Meta Analysis
72
Systematic Review
45
Rct
18
Clinical Trial
2
Narrative Review
1
Other
1
Guideline
1
Openfda Safety
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B Efficacy of statins for osteoporosis: a systematic review and meta-analysis
Meta Analysis Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 2017 PubMed DOI
B Drugs to reduce bleeding and transfusion in major open vascular or endovascular surgery: a systematic review and network meta-analysis
Systematic Review The Cochrane database of systematic reviews 2023 PubMed DOI
B Bisphosphonate therapy for osteogenesis imperfecta
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.