B12 Gummies 500 mcg by Sundown Naturals — Ingredients, Evidence & Safety

🟢 100/100

This product looks safe

No ingredients exceed tolerable upper intake levels
33% of ingredients have research evidence

A Label Compliance Grade

Product Label

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Label Data

2 Gummie(s) Serving Size

1 Servings

Vitamin Product Type

33% Evidence Coverage

Supplement Facts — Evidence Check

Calories

10 Calorie(s)

Total Carbohydrates

3 Gram(s) (1% DV)

Vitamin B12

500 mcg (20833% DV)

📊 208.3× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)

RDA 0.0024mg This product: 0.5mg

Other Ingredients

Corn Syrup Sugar Gelatin Contains <2% of

Label Claims — Verification

❓ All Other

❓ Structure/Function

All Other (99% of products) Structure/Function (89% of products) Nutrient (56% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free Dairy Free

Product Information

📋 Directions for Use

Directions: For adults, chew two (2) gummies daily, preferably with a meal.

⚠️ Warnings & Precautions

As a reminder, discuss the supplements and medications you take with your health care providers.

Warning: If you are pregnant, nursing, taking any medications or have any medical condition, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Keep out of reach of children.

Tamper Resistant: Do not use if packets is torn or open.

🧪 Formulation Notes

100% free of GMO Non-GMO No dairy/lactose No artificial flavors Certified GF Gluten-free

B12 Gummies 500 mcg per serving

Naturally sourced colors

No preservatives Stimulant free

Non-GMO. No gluten, no wheat, no milk, no lactose, no artificial flavor, no artificial sweetener, no preservatives, no soy, no starch, no yeast, no fish. Sodium free.

Additional Information

Certified GF Gluten-free

Energy support Raspberry, mixed berry & orange flavored

Sample packet

Smart facts

B vitamins aid in the conversion of food into energy

Store at room temperature and avoid excessive heat.

Made in the USA with select ingredients from around the world

18-75247

18-75247 B67282 00A

Not for retail sale

Product Details

DSLD Entry Date 2017-05-24

Product Type Vitamin

Form Gummy or Jelly

Brand Sundown Naturals

DSLD ID 73200

Data Updated 2026-04-11

Research Evidence

237 Research Sources

53 Avg Quality Score

83 Meta Analysis

74 Systematic Review

45 Rct

29 Clinical Trial

2 Guideline

2 Regulatory Source

1 Openfda Safety

A Associations between serum Homocysteine, vitamin B9, and vitamin B12 levels and the formation of intracranial Aneurysms: A systematic review and meta-analysis

Meta Analysis Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2025

PubMed DOI

A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies

Meta Analysis Critical reviews in food science and nutrition 2019

PubMed DOI

A Oral vitamin B12 versus intramuscular vitamin B12 for vitamin B12 deficiency

Systematic Review The Cochrane database of systematic reviews 2018

PubMed DOI Cochrane

A Effects of Vitamin B12 Supplementation on Cognitive Function, Depressive Symptoms, and Fatigue: A Systematic Review, Meta-Analysis, and Meta-Regression

Meta Analysis Nutrients 2021

PubMed DOI

A Efficacy of different routes of vitamin B12 supplementation for the treatment of patients with vitamin B12 deficiency: A systematic review and network meta-analysis

Systematic Review Irish journal of medical science 2024

PubMed DOI

B Helicobacter pylori infection and micronutrient deficiency in pregnant women: a systematic review and meta-analysis

Meta Analysis BMJ open gastroenterology 2020

PubMed DOI

B Vitamin B12 supplementation during pregnancy for maternal and child health outcomes

Systematic Review The Cochrane database of systematic reviews 2024

PubMed DOI Cochrane

B A comprehensive review and meta-regression analysis of randomized controlled trials examining the impact of vitamin B12 supplementation on homocysteine levels

Meta Analysis Nutrition reviews 2024

PubMed DOI

B Relationship between vitamin B12 levels and motor development: A systematic review

Systematic Review Clinical nutrition ESPEN 2024

PubMed DOI

B Vitamin B12, folate, and homocysteine in metabolic syndrome: a systematic review and meta-analysis

Meta Analysis Frontiers in endocrinology 2023

PubMed DOI

View all evidence for Vitamin B12 →