5-Methyl Folate 1,000 mcg
Review before taking
- Folate: 1.667mg is 1.7× the Tolerable Upper Intake Level (1.0mg)
- 100% of ingredients have research evidence
What the Evidence Says
AI-generated · Qwen 3.6 · grounded in 1 source · methodologyFolate is essential for DNA synthesis and cellular repair, with strong evidence supporting its role in supporting healthy homocysteine levels. However, the low evidence coverage for this specific formulation and a safety score of 60 suggest potential concerns regarding dosage or individual tolerance. Users should be aware of these limitations.
AI-generated summary based on research evidence. Not medical advice.
Safety Alerts
Folate: 1.667mg is 1.7× the Tolerable Upper Intake Level (1.0mg)
This product received a low safety score because it contains more folate than the recommended maximum daily limit for adults.
Product Label
Label Data
Supplement Facts — Evidence Check
Other Ingredients
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Product Information
Directions for Use
SUGGESTED USAGE: Take 1 tablet daily with a meal, or as directed by your healthcare practitioner.
Warnings & Precautions
CAUTIONS/INTERACTIONS: For adults only. The elderly and individuals with conditions that may impair vitamin B-12 absorption should frequently check vitamin B-12 status when taking this product as high-dose folic acid may mask vitamin B-12 deficiency.
Consult physician if pregnant/nursing, taking medication (especially phenobarbital, phenytoin, primidone, and methotrexate), or have a medical condition (especially any condition involving nutrient malabsorption).
Keep out of reach of children.
Do Not Eat Freshness Packet. Keep in Bottle.
Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish or tree nut ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.
Formulation Notes
This product utilizes a patented form of 5-MTHF with superior bioavailability.
~ Metabolically Active Folate*
Quatrefolic
Vegetarian/Vegan
Non-GMO
Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish or tree nut ingredients.
Additional Information
HOW IT WORKS: Folate consumed in the diet or from supplements must be converted to its active form, 5-Methyltetrahydrofolate (5-MTHF), to be used by the body. This is a multi-step biochemical process that, in some circumstances, may not be efficient enough to meet the body's needs. In addition, unlike folic acid, 5-MTHF can penetrate the blood-brain barrier.
Natural color variation may occur in this product.
CODE P0491 V3
~ Superior Bioavailability
Non-GMO
Product Details
Research Evidence
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.