🟢 90/100

This product looks safe

  • Contains proprietary blend — exact ingredient amounts not disclosed
  • Limited research evidence available for ingredients
B Label Compliance Grade

Product Label

📸

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Safety Alerts

ℹ️ Contains proprietary blend — exact ingredient amounts not disclosed

Label Data

2 Caplet(s) Serving Size
60 Servings
Other Combinations Product Type
0% Evidence Coverage

Supplement Facts — Evidence Check

📊 Market median: 500.0mg (143 products)
This product: 3000mg
Proprietary Blend {Combination}
150 mg

Other Ingredients

Calcium Phosphate cellulose esthers and composites Seaweed extract corn extract pectin Magnesium Stearate

Label Claims — Verification

All Other
Structure/Function
All Other (100% of products) Structure/Function (91% of products) Nutrient (35% of products)

Target Groups

Adult (18 - 50 Years) Sugar Free

Product Information

📋 Directions for Use

DAILY DOSING CHART (chart) FOR MEN UP TO 200 LBS - 8 CAPLETS 4 caplets 30 minutes before breakfast and again 30 minutes before lunch OVER 200 LBS - 10 CAPLETS 5 caplets 30 minutes before breakfast and again 30 minutes before lunch FOR WOMEN UP TO 125 LBS - 4 CAPLETS 2 caplets 30 minutes before breakfast and again 30 minutes before lunch OVER 125 LBS - 6 CAPLETS 3 caplets 30 minutes before breakfast and again 30 minutes before lunch

NOTE: To maximize results, drink at least 64 ounces of water daily while using NO2 Black.

⚠️ Warnings & Precautions

KEEP OUT OF THE REACH OF CHILDREN.

WARNING: Diabetics, women who are pregnant or nursing, individuals being treated for high blood pressure or serum glucose control or erectile dysfunction, individuals who are thiamin deficient, allergic to alpha-lipoic acid or other sulfur-containing compounds, or taking prescription drugs, should consult their physician before using this product. Use this product with caution if you have a history of cold sores. Use of this product is not recommended in individuals allergic to corn products, gluten, or citrus fruit. Not intended for use by individuals under the age of 18 years.

🧪 Formulation Notes

This product contains no yeast, wheat, soy, sugar or other sweeteners, artificial flavors, colors or preservatives.

Additional Information

PROTECT FROM LIGHT AND MOISTURE

STORE AT 59-86°F (15-30°C).

ACTINOS2 is a trademark of Glanbia plc.

ARGININE ALPHA-KETOGLUTARATE

BLACK

CLINICALLY TESTED

EXTENDED-RELEASE FORMULA

HINT: NO2 Black is ideal to stack with CE2.

NOS-ENHANCED HEMODILATOR*

Rev. 121806

U.S. PATENT NO. 6,905,707

ArginPure(TM) by Degussa(R)

pHylex9(TM) Extended-Release Delivery Technology

UP-REGULATED WITH: ACTINOS2(TM) NOS-Enhancing Peptide Fraction

Product Details

UPC / SKU 6 33012 80003 2
DSLD Entry Date 2012-03-23
Product Type Other Combinations
Form Other (e.g. tea bag)
Brand MRI
DSLD ID 6640
Data Updated 2026-04-11

Research Evidence

45 Research Sources
52 Avg Quality Score
12 Rct
11 Systematic Review
11 Meta Analysis
11 Clinical Trial
A Nitric oxide donors (nitrates), L-arginine, or nitric oxide synthase inhibitors for acute stroke
Meta Analysis The Cochrane database of systematic reviews 2017
A Arginine supplementation for prevention of necrotising enterocolitis in preterm infants
Meta Analysis The Cochrane database of systematic reviews 2017
B Nutritional interventions for treating foot ulcers in people with diabetes
Meta Analysis The Cochrane database of systematic reviews 2020
B Nitric oxide donors (nitrates), L-arginine, or nitric oxide synthase inhibitors for acute stroke
Systematic Review The Cochrane database of systematic reviews 2002
B Arginine supplementation for prevention of necrotising enterocolitis in preterm infants
Systematic Review The Cochrane database of systematic reviews 2007
B The Effect of Amino Acids on Wound Healing: A Systematic Review and Meta-Analysis on Arginine and Glutamine
Meta Analysis Nutrients 2021
B Nitric oxide donors (nitrates), L-arginine, or nitric oxide synthase inhibitors for acute ischaemic stroke
Systematic Review The Cochrane database of systematic reviews 2000
B Dietary Supplements for Erectile Dysfunction: Analysis of Marketed Products, Systematic Review, Meta-Analysis and Rational Use
Meta Analysis Nutrients 2023
B Arginine supplementation for prevention of necrotising enterocolitis in preterm infants
Systematic Review The Cochrane database of systematic reviews 2004
B An Analysis of Popular Online Erectile Dysfunction Supplements
Systematic Review The journal of sexual medicine 2019
View all evidence for L Arginine →

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