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Melatonin Plus

product on market Tablet or Pill Schiff Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Melatonin and L-theanine are supported by moderate evidence for promoting sleep onset and relaxation. Vitamin B6 contributes to the synthesis of neurotransmitters involved in sleep regulation. Overall, research for these ingredients is well-established, though evidence coverage for this specific formulation is limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Melatonin Plus
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Tablet(s)
Serving Size
Non-Nutrient/Non-Botanical
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

10 mg (500% DV)
7.7× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
25 mg
Market median: 200.0mg (358 products) 9 studies (A:0, B:2)
3 mg
Market median: 3.0mg (984 products) 240 studies (A:2, B:109)

Other Ingredients

Cellulose Dicalcium Phosphate Coating Calcium Carbonate Croscarmellose Sodium Magnesium Stearate Silicon Dioxide
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: For best results, take one (1) tablet at bedtime or as recommended by your health care professional.

Warnings & Precautions

Keep out of reach of children.

WARNING: Not intended for use by pregnant or lactating women, individuals with autoimmune conditions, depressive disorders, endocrine disorders, serious illness, or other drug use. Seek advice from your health practitioner prior to use if under medical supervision, taking tranquilizers or sedatives or taking more than 10 mg of melatonin per day.

Do not use before or while operating a motor vehicle or heavy machinery.

Not to be taken by individuals under the age of 18.

Formulation Notes

Schiff has added L-Theanine, a natural compound found in green tea, for its calming and stress relief properties.

Melatonin Plus is also drug free.

GUARANTEED: No added sugar (sucrose, fructose, lactose), salt (sodium chloride), yeast, wheat, gluten or milk. No preservatives or artificial flavors.

3 mg Melatonin 25 mg Theanine

With Theanine

Additional Information

For information call: 1-800-526-6251 (8am-5pm MST M–F)

Melatonin helps maintain regular sleeping patterns.

Store in a cool, dry place with lid tightly closed.

GUARANTEED for purity, freshness and labeled potency.

Schiff Quality Guarantee

Since 1936

New look

Supports normal sleep patterns

Over 75 years of wellness

127453 466127453.6

Metadata

Product Details

UPC / SKU0 20525 12745 7
DSLD Entry Date2016-10-22
Product TypeNon-Nutrient/Non-Botanical
FormTablet or Pill
BrandSchiff
DSLD ID65369
Data Updated2026-04-11
Research

Research Evidence

291
Research Sources
55
Avg Quality
129
Meta Analysis
93
Systematic Review
51
Rct
11
Clinical Trial
2
Other
2
Regulatory Source
1
Openfda Safety
A Interventions for preventing delirium in hospitalised non-ICU patients
Meta Analysis The Cochrane database of systematic reviews 2016 PubMed DOI
A Melatonin for preoperative and postoperative anxiety in adults
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Effect of melatonin on quality of life and symptoms in patients with cancer: a systematic review and meta-analysis of randomised controlled trials
Meta Analysis BMJ open 2022 PubMed DOI
B Pharmacological interventions for prevention of weight gain in people with schizophrenia
Meta Analysis The Cochrane database of systematic reviews 2022 PubMed DOI
B Melatonin for pre- and postoperative anxiety in adults
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
B Prevention of depression in adults with long-term physical conditions
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
B Comparative effects of pharmacological interventions for the acute and long-term management of insomnia disorder in adults: a systematic review and network meta-analysis
Systematic Review Lancet (London, England) 2022 PubMed DOI
B Does melatonin administration reduce the incidence of postoperative delirium in adults? Systematic review and meta-analysis
Meta Analysis BMJ open 2023 PubMed DOI
B Second-generation antidepressants for preventing seasonal affective disorder in adults
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
B Interventions for preventing type 2 diabetes in adults with mental disorders in low- and middle-income countries
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.