🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 67% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

1 Tablet(s) Serving Size
120 Servings
Non-Nutrient/Non-Botanical Product Type
67% Evidence Coverage

Supplement Facts — Evidence Check

📊 Market median: 1000.0mg (1115 products) 📚 22 studies (Tier A: 0, B: 9)
This product: 375mg
📊 Market median: 600.0mg (79 products) 📚 24 studies (Tier A: 0, B: 6)
This product: 300mg
MSM
375 mg
📊 Market median: 1000.0mg (2 products)
This product: 375mg

Other Ingredients

Cellulose modified Cellulose Gum Stearic Acid Magnesium Stearate Silica Glycerin

Label Claims — Verification

All Other
Structure/Function
All Other (100% of products) Structure/Function (89% of products) Nutrient (16% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

SUGGESTED USE: Take one tablet daily with food up to three times daily.

⚠️ Warnings & Precautions

KEEP OUT OF REACH OF CHILDREN.

🧪 Formulation Notes

CONTAINS NO artificial colors, flavors or preservatives; no wheat, gluten, milk, eggs, peanuts, tree nuts, soy, or fish.

This product contains glucosamine sulfate from shell fish.

Additional Information

Glucosamine is a building block of joint tissue, and helps the body manufacture substances necessary for healthy joints. Chondroitin is a natural extract from beef cartilage and helps fight the breakdown of tissue and cartilage in the body. MSM provides naturally occurring organic sulfur, which is a necessary component for making collagen, a primary constituent of joints, cartilage and other connective tissues. Used in combination, our Glucosamine Chondroitin MSM formula provides a convenient supplement to support healthy joints.

Glucosamine, chondroitin, and MSM are three popular ingredients that are combined to provide comprehensive joint support. Our glucosamine complex provides a special blend of three sources of glucosamine, including glucosamine sulfate, n-acetyl d-glucosamine, and glucosamine hydrochloride.

Supports Healthy Joints

WE GUARANTEE OUR SUPPLEMENTS FOR POTENCY AND PURITY

DOUBLE VERIFIED GLUTEN FREE(TM)

OptiMSM(R)

839J

Product Details

UPC / SKU 7 19985 83943 6
DSLD Entry Date 2012-03-23
Product Type Non-Nutrient/Non-Botanical
Form Tablet or Pill
DSLD ID 6452
Data Updated 2026-04-11

Research Evidence

39 Research Sources
50 Avg Quality Score
20 Rct
9 Meta Analysis
4 Clinical Trial
3 Systematic Review
1 Regulatory Source
1 Openfda Safety
B Interventions for the management of temporomandibular joint osteoarthritis
Systematic Review The Cochrane database of systematic reviews 2012
B Glucosamine therapy for treating osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2005
B Chondroitin for osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2015
B Efficacy and safety of the combination of glucosamine and chondroitin for knee osteoarthritis: a systematic review and meta-analysis
Meta Analysis Archives of orthopaedic and trauma surgery 2023
B Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis
Rct The New England journal of medicine 2006
B Oral Glucosamine in the Treatment of Temporomandibular Joint Osteoarthritis: A Systematic Review
Systematic Review International journal of molecular sciences 2023
B Scientific Opinion on glucosamine and joint health
Regulatory Source EFSA Journal 2009
B Clinical Efficacy and Safety of Chondroitin Combined with Glucosamine in the Treatment of Knee Osteoarthritis: A Systematic Review and Meta-Analysis
Meta Analysis Computational and mathematical methods in medicine 2022
B Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib
Rct Annals of the rheumatic diseases 2016
B Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trials
Meta Analysis Journal of orthopaedic surgery and research 2018
View all evidence for Glucosamine →

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