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Pycnogenol And Grape Seed Extract 50 mg

product on market Tablet or Pill Source Naturals Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 33% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

French maritime pine bark and grape seed extracts provide antioxidant support with moderate evidence for improving circulation and vascular health. Calcium is a well-established mineral essential for bone density and neuromuscular function. Research coverage for this specific combination is limited, though the individual components are generally recognized as safe.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Pycnogenol And Grape Seed Extract 50 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Tablet(s)
Serving Size
15
Servings
Botanical with Nutrients
Product Type
33%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calcium
42 mg (4% DV)
French Maritime Pine Bark Extract
50 mg
Market median: 100.0mg (284 products) 10 studies (A:0, B:4)

Other Ingredients

Microcrystalline Cellulose Dibasic Calcium Phosphate Stearic Acid modified Cellulose Gum Silicon Dioxide, Colloidal Magnesium Stearate
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested Use: 2 to 4 tablets daily.

Warnings & Precautions

Do not use if either tamper-evident seal is broken or missing. Keep out of the reach of children.

NOTE: If you are pregnant, may become pregnant, or breastfeeding, consult your health care professional before using this product.

Additional Information

Both compounds are rich in proanthocyanidins, a special class of water-soluble bioflavonoids which are excellent free radical scavengers. Proanthocyanidins are believed to play an important role in maintaining good health.*

SN0517 REV K071

Metadata

Product Details

UPC / SKU0 21078 00517 9
DSLD Entry Date2011-10-26
Product TypeBotanical with Nutrients
FormTablet or Pill
DSLD ID644
Data Updated2026-04-11
Research

Research Evidence

14
Research Sources
50
Avg Quality
9
Rct
2
Meta Analysis
2
Clinical Trial
1
Systematic Review
B Low Dose Monacolin K Combined with Coenzyme Q10, Grape Seed, and Olive Leaf Extracts Lowers LDL Cholesterol in Patients with Mild Dyslipidemia: A Multicenter, Randomized Controlled Trial
Rct Nutrients 2023 PubMed DOI
B Efficacy of Bilberry and Grape Seed Extract Supplement Interventions to Improve Glucose and Cholesterol Metabolism and Blood Pressure in Different Populations-A Systematic Review of the Literature
Systematic Review Nutrients 2021 PubMed DOI
B The effect of grape seed extract on cardiovascular risk markers: a meta-analysis of randomized controlled trials
Meta Analysis Journal of the American Dietetic Association 2011 PubMed DOI
B The impact of grape seed extract treatment on blood pressure changes: A meta-analysis of 16 randomized controlled trials
Meta Analysis Medicine 2016 PubMed DOI
B Grape Seed Extract Positively Modulates Blood Pressure and Perceived Stress: A Randomized, Double-Blind, Placebo-Controlled Study in Healthy Volunteers
Rct Nutrients 2021 PubMed DOI
C Effects of grape seed extract beverage on blood pressure and metabolic indices in individuals with pre-hypertension: a randomised, double-blinded, two-arm, parallel, placebo-controlled trial
Rct The British journal of nutrition 2016 PubMed DOI
C Effect of grape seed extract on blood pressure in subjects with the metabolic syndrome
Rct Metabolism: clinical and experimental 2009 PubMed DOI
C Grape seed extract supplementation along with a restricted-calorie diet improves cardiovascular risk factors in obese or overweight adult individuals: A randomized, placebo-controlled trial
Rct Phytotherapy research : PTR 2021 PubMed DOI
C The effect of polyphenol-rich chardonnay seed supplements on peripheral endothelial function.
Rct European journal of nutrition PubMed DOI
C The effects of grape seed extract supplementation on cardiovascular risk factors, liver enzymes and hepatic steatosis in patients with non-alcoholic fatty liver disease: a randomised, double-blind, placebo-controlled study.
Rct BMC complementary medicine and therapies PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.