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Grapenol

product on market Tablet or Pill Douglas Laboratories Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Grape seed, skin, and stem extracts contain polyphenols and proanthocyanidins that may support antioxidant activity and cardiovascular health. Research evidence for these specific effects is generally moderate. This ingredient profile is associated with a high safety score.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Grapenol
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Tablet(s)
Serving Size
90
Servings
Botanical
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Market median: 100.0mg (284 products) 10 studies (A:0, B:4)

Other Ingredients

Microcrystalline Cellulose Rice Starch Stearic Acid Silica Magnesium Stearate
Claims

Label Claims — Verification

Unverified All Other
Info

Product Information

Directions for Use

Suggested Usage: As a dietary supplement, adults take 1 to 3 tablets daily with food, or as directed by your healthcare professinal.

Warnings & Precautions

KEEP OUT OF REACH OF CHILDREN.

Tamper resistant package, do not use if outer seal is missing.

Additional Information

For optimal storage conditions, store in a cool, dry place. (59(0)-77(0)F/15(0)-25(0)C) (35-65% relative humidity)

GRP9

amni(R) original formula

Metadata

Product Details

UPC / SKU7 45287 02121 7
DSLD Entry Date2012-02-23
Product TypeBotanical
FormTablet or Pill
BrandDouglas Laboratories
DSLD ID6235
Data Updated2026-04-11
Research

Research Evidence

14
Research Sources
50
Avg Quality
9
Rct
2
Meta Analysis
2
Clinical Trial
1
Systematic Review
B Low Dose Monacolin K Combined with Coenzyme Q10, Grape Seed, and Olive Leaf Extracts Lowers LDL Cholesterol in Patients with Mild Dyslipidemia: A Multicenter, Randomized Controlled Trial
Rct Nutrients 2023 PubMed DOI
B Efficacy of Bilberry and Grape Seed Extract Supplement Interventions to Improve Glucose and Cholesterol Metabolism and Blood Pressure in Different Populations-A Systematic Review of the Literature
Systematic Review Nutrients 2021 PubMed DOI
B The effect of grape seed extract on cardiovascular risk markers: a meta-analysis of randomized controlled trials
Meta Analysis Journal of the American Dietetic Association 2011 PubMed DOI
B The impact of grape seed extract treatment on blood pressure changes: A meta-analysis of 16 randomized controlled trials
Meta Analysis Medicine 2016 PubMed DOI
B Grape Seed Extract Positively Modulates Blood Pressure and Perceived Stress: A Randomized, Double-Blind, Placebo-Controlled Study in Healthy Volunteers
Rct Nutrients 2021 PubMed DOI
C Effects of grape seed extract beverage on blood pressure and metabolic indices in individuals with pre-hypertension: a randomised, double-blinded, two-arm, parallel, placebo-controlled trial
Rct The British journal of nutrition 2016 PubMed DOI
C Effect of grape seed extract on blood pressure in subjects with the metabolic syndrome
Rct Metabolism: clinical and experimental 2009 PubMed DOI
C Grape seed extract supplementation along with a restricted-calorie diet improves cardiovascular risk factors in obese or overweight adult individuals: A randomized, placebo-controlled trial
Rct Phytotherapy research : PTR 2021 PubMed DOI
C The effect of polyphenol-rich chardonnay seed supplements on peripheral endothelial function.
Rct European journal of nutrition PubMed DOI
C The effects of grape seed extract supplementation on cardiovascular risk factors, liver enzymes and hepatic steatosis in patients with non-alcoholic fatty liver disease: a randomised, double-blind, placebo-controlled study.
Rct BMC complementary medicine and therapies PubMed DOI
View all evidence for Grape Seed →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.