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Glucosamine HCl 1500 mg MSM 1500 mg

product on market Other (e.g. tea bag) Rexall Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 20% of ingredients have research evidence
B Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Glucosamine hydrochloride and MSM are commonly used to support joint health and reduce inflammation. Research provides moderate evidence that these ingredients may help manage osteoarthritis symptoms. However, the overall evidence coverage for this specific formulation remains very limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Glucosamine HCl 1500 mg MSM 1500 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Caplet(s)
Serving Size
30
Servings
Non-Nutrient/Non-Botanical
Product Type
20%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calories
5 Calorie(s)
Total Carbohydrates
1 Gram(s) (1% DV)
Sodium
5 mg (1% DV)
Market median: 1000.0mg (1115 products) 24 studies (A:0, B:9)
MSM
1500 mg
Market median: 1000.0mg (2 products)

Other Ingredients

Cellulose Hypromellose Contains <2% of:
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: For adults, take two (2) caplets daily, preferably with a meal.

Warnings & Precautions

Warning: If you are pregnant, nursing, taking any medications or have any medical condition, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Keep out of reach of children.

Tamper resistant: Do not use if seal under cap is broken or missing.

As a reminder, discuss the supplements and medications you take with your health care providers.

Contains Shellfish (Shrimp, Crab, Lobster, Crayfish) ingredients.

Formulation Notes

No Gluten, no Yeast, no Wheat, no Milk or Milk derivatives, no Lactose, no Sugar, no Preservatives, no Soy, no Artificial Color, no Artificial Flavor.

Glucosamine HCl 1500 mg MSM 1500 mg per serving

Contains Shellfish (Shrimp, Crab, Lobster, Crayfish) ingredients.

Additional Information

Important facts you should know Glucosamine and MSM is an effective supplement combination that helps support maximum flexibility and range of motion. Together, this powerful duo promotes healthy cartilage to support fluid joint movement. Glucosamine is a key structural component in cartilage which is needed for healthy structure and function of joints. MSM (Methylsulfonylmethane) is a natural source of sulfur and works in conjunction with Glucosamine to support healthy joints and connective tissue. MSM supports Glucosamine's effectiveness for cartilage health. Noticeable improvement in flexibility and range of motion should be expected after taking this supplement as directed on a consistent basis. Individual results may vary.

Store at room temperature and avoid excessive heat.

Quality guaranteed lab tested Laboratory tested to meet strict quality control standards for potency, purity and disintegration. 100% Quality guaranteed.

A0317 N

Actual size

Prod. No. 53181 04B B53191

Since 1903

Joint health & mobility

Quality guaranteed

Metadata

Product Details

UPC / SKU3 01220 53181 8
DSLD Entry Date2016-08-24
Product TypeNon-Nutrient/Non-Botanical
FormOther (e.g. tea bag)
BrandRexall
DSLD ID63366
Data Updated2026-04-11
Research

Research Evidence

39
Research Sources
50
Avg Quality
20
Rct
9
Meta Analysis
4
Clinical Trial
3
Systematic Review
1
Regulatory Source
1
Openfda Safety
B Interventions for the management of temporomandibular joint osteoarthritis
Systematic Review The Cochrane database of systematic reviews 2012 PubMed DOI
B Glucosamine therapy for treating osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2005 PubMed
B Chondroitin for osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
B Efficacy and safety of the combination of glucosamine and chondroitin for knee osteoarthritis: a systematic review and meta-analysis
Meta Analysis Archives of orthopaedic and trauma surgery 2023 PubMed DOI
B Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis
Rct The New England journal of medicine 2006 PubMed
B Oral Glucosamine in the Treatment of Temporomandibular Joint Osteoarthritis: A Systematic Review
Systematic Review International journal of molecular sciences 2023 PubMed DOI
B Scientific Opinion on glucosamine and joint health
Regulatory Source EFSA Journal 2009 DOI
B Clinical Efficacy and Safety of Chondroitin Combined with Glucosamine in the Treatment of Knee Osteoarthritis: A Systematic Review and Meta-Analysis
Meta Analysis Computational and mathematical methods in medicine 2022 PubMed DOI
B Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib
Rct Annals of the rheumatic diseases 2016 PubMed DOI
B Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trials
Meta Analysis Journal of orthopaedic surgery and research 2018 PubMed DOI
View all evidence for Glucosamine →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.