Premama Fertility Unflavored by Premama — Ingredients, Evidence & Safety

🟢 100/100

This product looks safe

No ingredients exceed tolerable upper intake levels
33% of ingredients have research evidence

A Label Compliance Grade

Product Label

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Label Data

2.2 Gram(s) Serving Size

28 Servings

Other Combinations Product Type

33% Evidence Coverage

Supplement Facts — Evidence Check

Calories

9 Calorie(s)

Fat

Carbohydrates

2 Gram(s)

Protein

Folic Acid

200 mcg (50% DV)

✅ Within RDA (0.5× RDA of 0.4 mg) 📚 225 studies (Tier A: 10, B: 105)

RDA 0.4mg This product: 0.2mg UL 1.0mg

Myo-Inositol

2000 mg

📊 Market median: 550.0mg (217 products) 📚 29 studies (Tier A: 0, B: 5)

This product: 2000mg

Label Claims — Verification

❓ Nutrient

❓ All Other

❓ Structure/Function

All Other (99% of products) Structure/Function (77% of products) Nutrient (60% of products) Approved Health (5% of products)

Target Groups

Vegan Vegetarian Adult Female (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

Directions: Use daily. Mix one packet with at least 12oz of liquid. Blend well to completely dissolve. Enjoy Premama any of these refreshing ways: Mix it with water, shake and drink. Mix it with any noncarbonated beverage. Blend it into your favorite smoothie.

⚠️ Warnings & Precautions

As with any supplement, if you are pregnant, nursing or taking medication, consult your doctor before use.

Keep out of reach of children.

Do not use this product if safety seal on flap is torn or missing.

🧪 Formulation Notes

Healthy natural ovulation support with Myo-Inositol

Folic Acid to help support prenatal health. Myo-Inositol to help support healthy, natural ovulation.

GF Gluten Free

V Vegan

Non-GMO

Additional Information

Made and packaged in the USA from domestic and imported ingredients

Store at room temperature. Avoid excessive heat.

Look for these other Premama products: Essentials - Essentials + DHA Lactation - Digestive Aid

May help improve egg quality Clinically studied based on Professional Studies Performed in Europe

Easy to drink, easy on your stomach

GF Gluten Free

V Vegan

Non-GMO

Product Details

UPC / SKU 8 56420 00404 9

DSLD Entry Date 2016-08-24

Product Type Other Combinations

Form Powder

Brand Premama

DSLD ID 63323

Data Updated 2026-04-11

Research Evidence

363 Research Sources

57 Avg Quality Score

187 Meta Analysis

56 Systematic Review

54 Rct

29 Guideline

26 Clinical Trial

6 Cochrane Review

2 Regulatory Source

1 Other

1 Openfda Safety

A Homocysteine-lowering interventions for preventing cardiovascular events

Meta Analysis The Cochrane database of systematic reviews 2017

PubMed DOI

A Community-based intervention packages for reducing maternal and neonatal morbidity and mortality and improving neonatal outcomes

Meta Analysis The Cochrane database of systematic reviews 2015

PubMed DOI

A Folate Intake and Risk of Pancreatic Cancer: A Systematic Review and Updated Meta-Analysis of Epidemiological Studies

Meta Analysis Digestive diseases and sciences 2021

PubMed DOI

A The Association Between the Risk of Hypertensive Disorders of Pregnancy and Folic Acid: A Systematic Review and Meta-Analysis

Meta Analysis Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 2021

PubMed DOI

A A Comparative Study Evaluating the Effectiveness of Folate-Based B Vitamin Intervention on Cognitive Function of Older Adults under Mandatory Folic Acid Fortification Policy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Meta Analysis Nutrients 2024

PubMed DOI

A Associations between serum Homocysteine, vitamin B9, and vitamin B12 levels and the formation of intracranial Aneurysms: A systematic review and meta-analysis

Meta Analysis Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2025

PubMed DOI

A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies

Meta Analysis Critical reviews in food science and nutrition 2019

PubMed DOI

A Beneficial effects of folic acid supplementation on lipid markers in adults: A GRADE-assessed systematic review and dose-response meta-analysis of data from 21,787 participants in 34 randomized controlled trials

Meta Analysis Critical reviews in food science and nutrition 2022

PubMed DOI

A Folic acid supplementation and blood pressure: a GRADE-assessed systematic review and dose-response meta-analysis of 41,633 participants

Meta Analysis Critical reviews in food science and nutrition 2023

PubMed DOI

A Digital tracking, provider decision support systems, and targeted client communication via mobile devices to improve primary health care

Meta Analysis The Cochrane database of systematic reviews 2025

PubMed DOI

View all evidence for Folate →