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Homocysteine Resist

product on market Capsule Life Extension Safety: 87/100
87/100

This product is generally safe

  • Vitamin B6: 250mg is 2.5× the Tolerable Upper Intake Level (100mg)
  • 100% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Vitamin B6, folate, and B12 are supported by strong evidence for their role in lowering homocysteine levels. These nutrients act as essential cofactors in the methionine cycle to maintain cardiovascular and neurological health. Research indicates these ingredients are generally safe and effective for managing homocysteine concentrations.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Vitamin B6: 250mg is 2.5× the Tolerable Upper Intake Level (100mg)

Label

Product Label

Label for Homocysteine Resist
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Vegetarian Capsule(s)
Serving Size
Vitamin
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

250 mg (12500% DV)
Exceeds UL by 2.5× (UL: 100 mg) 114 studies (A:3, B:35)
400 mcg (100% DV)
Within RDA (1.0× RDA) 226 studies (A:10, B:105)
500 mcg (8333% DV)
208.3× RDA — above typical dose 139 studies (A:1, B:44)

Other Ingredients

Vegetable Cellulose Microcrystalline Cellulose Silica Vegetable Stearate
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Read the entire label and follow the directions carefully prior to use. Directions: Take one (1) capsule daily with food, or as recommended by a healthcare practitioner.

Warnings & Precautions

Caution: Vitamin B deficiency occurs in 30% of seniors and 55% of the elderly and is correlated with elevated homocysteine levels. Do not use this product if your homocysteine levels are at or below acceptable levels. Consuming more than 2000 mg of vitamin B6 daily can result in loss of muscle coordination, tingling sensations in the extremities, and degeneration of nerve tissue. Similar effects may be experienced if more than 200-300 mg of B6 is consumed per day over the course of months or years, especially if taken without other B complex vitamins.

Consult your physician before using this product if you are taking levodopa (L-dopa).

Warnings: - Keep out of reach of children.

- Do not exceed recommended dose. - Do not purchase if outer seal is broken or damaged.

- When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

Additional Information

Scan for product info

Q01435D

Maintains healthy arteries

To report a serious adverse event or obtain product information, contact 1-866-280-2852.

Store tightly closed in a cool, dry place.

Metadata

Product Details

UPC / SKU7 37870 14351 2
DSLD Entry Date2016-06-24
Product TypeVitamin
FormCapsule
DSLD ID61996
Data Updated2026-04-11
Research

Research Evidence

153
Research Sources
55
Avg Quality
71
Systematic Review
51
Meta Analysis
19
Rct
6
Clinical Trial
2
Other
2
Regulatory Source
1
Openfda Safety
A Efficacy of vitamin and antioxidant supplements in prevention of cardiovascular disease: systematic review and meta-analysis of randomised controlled trials
Meta Analysis BMJ (Clinical research ed.) 2013 PubMed DOI
A Homocysteine lowering interventions for preventing cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2009 PubMed DOI
A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
Meta Analysis Critical reviews in food science and nutrition 2019 PubMed DOI
A Exploring the causal associations of micronutrients on urate levels and the risk of gout: A Mendelian randomization study
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
A Pyridoxine (vitamin B6) supplementation during pregnancy or labour for maternal and neonatal outcomes
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
B Prophylactic drug management for febrile seizures in children
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
B Treatments for Hyperemesis Gravidarum and Nausea and Vomiting in Pregnancy: A Systematic Review
Systematic Review JAMA 2016 PubMed DOI
B The potential role of nutritional components in improving brain function among patients with Alzheimers disease: a meta-analysis of RCT studies
Meta Analysis Neurosciences (Riyadh, Saudi Arabia) 2020 PubMed DOI
B Pyridoxine (vitamin B6) supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2006 PubMed
B Effect of ginger in the treatment of nausea and vomiting compared with vitamin B6 and placebo during pregnancy: a meta-analysis
Meta Analysis The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2022 PubMed DOI
View all evidence for Vitamin B6 →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.