Super Omega-3 EPA/DHA With Sesame Lignans & Olive Fruit Extract by Life Extension — Ingredients, Evidence & Safety

Product Label

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Label Data

2 Softgel(s) Serving Size

60 Servings

Other Combinations Product Type

29% Evidence Coverage

Supplement Facts — Evidence Check

Calories

25 Calorie(s)

Total Fat

2.5 Gram(s) (4% DV)

Saturated Fat

Cholesterol

5 mg (2% DV)

Pure+ Wild Fish Oil concentrate

2000 mg

📊 Market median: 750.0mg (447 products) 📚 388 studies (Tier A: 18, B: 204)

This product: 2000mg UL 3000mg

Polyphen-Oil Olive extract

300 mg

Sesame Seed Lignan Extract

10 mg

📊 Market median: 200.0mg (52 products) 📚 10 studies (Tier A: 0, B: 6)

This product: 10mg

Other Ingredients

highly refined Fish Oil concentrate Gelatin Glycerin Aqueous Enteric Coating purified Water Silica Maltodextrin Caramel color Sunflower Lecithin Mixed Tocopherols Rosemary extract

Label Claims — Verification

❓ All Other

❓ Structure/Function

All Other (100% of products) Structure/Function (83% of products) Nutrient (6% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

Read the entire label and follow the directions carefully prior to use. DIRECTIONS: Take two (2) enteric coated softgels twice daily with meals, or as recommended by a healthcare practitioner.

⚠️ Warnings & Precautions

CAUTION: If you are taking anti-coagulant or anti-platelet medications, or have a bleeding disorder, consult your healthcare provider before taking this product.

WARNINGS: ~ KEEP OUT OF REACH OF CHILDREN.

~ DO NOT EXCEED RECOMMENDED DOSE. ~ Do not purchase if outer seal is broken or damaged.

~ When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

🧪 Formulation Notes

non-GMO

Additional Information

Scan for product info

Store tightly closed in a cool, dry place.

MOLECULARLY DISTILLED

IFOS 5-Star Rating

To report a serious adverse event or obtain product information, contact 1-866-280-2852.

ENTERIC COATED*

*Enteric Coated for Sensitive Stomachs

QE01484I

Product Details

UPC / SKU 7 37870 14841 8

DSLD Entry Date 2016-06-24

Product Type Other Combinations

Form Softgel Capsule

Brand Life Extension

DSLD ID 60673

Data Updated 2026-04-11

Research Evidence

12 Research Sources

58 Avg Quality Score

8 Meta Analysis

3 Systematic Review

1 Rct

B S-adenosyl-L-methionine for alcoholic liver diseases

Meta Analysis The Cochrane database of systematic reviews 2006

PubMed

B S-adenosyl methionine (SAMe) for depression in adults

Meta Analysis The Cochrane database of systematic reviews 2016

PubMed

B Systemic juvenile idiopathic arthritis and adult-onset Still's disease are the same disease: evidence from systematic reviews and meta-analyses informing the 2023 EULAR/PReS recommendations for the diagnosis and management of Still's disease

Meta Analysis Annals of the rheumatic diseases 2024

PubMed DOI

B SAMe-TT2R2 Score to Predict Time in Therapeutic Range of Vitamin K Antagonists in Asian and Non-Asian patients: A Systematic Review and Meta-analysis

Meta Analysis American journal of cardiovascular drugs : drugs, devices, and other interventions 2024

PubMed DOI

B S-Adenosylmethionine (SAMe) as an adjuvant therapy for patients with depression: An updated systematic review and meta-analysis

Meta Analysis General hospital psychiatry 2024

PubMed DOI

B S-adenosyl-L-methionine for alcoholic liver diseases

Systematic Review The Cochrane database of systematic reviews 2001

PubMed

B WITHDRAWN: S-adenosyl-L-methionine for alcoholic liver diseases

Meta Analysis The Cochrane database of systematic reviews 2015

PubMed DOI

C S-adenosyl-L-methionine for the treatment of chronic liver disease: a systematic review and meta-analysis