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Vitamin D3 & K2

product on market Capsule The Vitamin Shoppe Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 67% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

Vitamin D3 and K2 work synergistically to support calcium absorption and bone mineralization. Strong evidence indicates that D3 facilitates calcium uptake while K2 directs it into the bone matrix. This combination is widely researched for maintaining skeletal health and cardiovascular function.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Vitamin D3 & K2
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
Other Combinations
Product Type
67%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

2500 IU (625% DV)
4.2× RDA — above typical dose (UL: 0.1 mg) 608 studies (A:16, B:251)
90 mcg (113% DV)
Within RDA (0.8× RDA) 275 studies (A:9, B:175)
Calcium
100 mg (10% DV)

Other Ingredients

Gelatin Microcrystalline Cellulose Magnesium Stearate Silica
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

DIRECTIONS: As a dietary supplement, take one (1) capsule two times daily, preferably with meals.

Warnings & Precautions

WARNING: Consult your healthcare provider prior to use if you are pregnant, nursing, taking any medication or have any medical conditions.

KEEP OUT OF REACH OF CHILDREN.

TAMPER EVIDENT Do not use if outer seal is broken or missing.

Formulation Notes

Does not contain: Yeast, Wheat, Gluten, Soy, Dairy, Citrus, Fish, Preservatives, Artificial Colors or Flavors.

gluten free dairy free soy free nut free

Additional Information

STORE IN A COOL, DRY PLACE.

Visit www.vitaminshoppe.com or call 1-800-223-1216 for more information and to reorder.

Item No. VS-3450 2022788 AP 52

vitamin

bone- cardiovascular- immune-

{capsule} actual size

Metadata

Product Details

UPC / SKU7 66536 03450 5
DSLD Entry Date2016-02-23
Product TypeOther Combinations
FormCapsule
BrandThe Vitamin Shoppe
DSLD ID56949
Data Updated2026-04-11
Research

Research Evidence

872
Research Sources
53
Avg Quality
309
Meta Analysis
309
Clinical Trial
111
Rct
71
Systematic Review
55
Guideline
4
Cochrane Review
4
Regulatory Source
2
Other
2
Narrative Review
2
Observational
1
Openfda Safety
A Vitamin D and vitamin D analogues for preventing fractures associated with involutional and post-menopausal osteoporosis
Meta Analysis The Cochrane database of systematic reviews 2009 PubMed DOI
A Vitamin D supplementation for prevention of mortality in adults
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Vitamin D and vitamin D analogues for preventing fractures in post-menopausal women and older men
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Vitamin D supplementation for prevention of cancer in adults
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Interventions for preventing falls in older people in care facilities and hospitals
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Drugs for preventing lung cancer in healthy people
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Vitamin D supplementation for prevention of mortality in adults
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A High prevalence of vitamin D deficiency in Asia: A systematic review and meta-analysis
Meta Analysis Critical reviews in food science and nutrition 2023 PubMed DOI
A The effect of vitamin D supplementation on depressive symptoms in adults: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Critical reviews in food science and nutrition 2023 PubMed DOI
A Interventions for preventing falls in older people living in the community
Meta Analysis The Cochrane database of systematic reviews 2009 PubMed DOI
View all evidence for Vitamin D →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.