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Chondroitin Sulfate 500 mg

product on market Tablet or Pill The Vitamin Shoppe Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 50% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

Chondroitin sulfate is used to support joint health, though research evidence for its efficacy is generally considered limited to moderate. The inclusion of sodium, calcium, and phosphorus provides basic mineral support. Overall, clinical evidence for this specific ingredient profile is sparse.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Chondroitin Sulfate 500 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Tablet(s)
Serving Size
Other Combinations
Product Type
50%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Sodium
39 mg (2% DV)
Calcium
123 mg (12% DV)
95 mg (10% DV)
Within RDA (0.1× RDA) 13 studies (A:0, B:3)
Market median: 600.0mg (79 products) 25 studies (A:0, B:6)

Other Ingredients

Microcrystalline Cellulose Stearic Acid Croscarmellose Sodium Magnesium Stearate Pharmaceutical Glaze
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

DIRECTIONS: As a dietary supplement, take one (1) to three (3) tablets daily, preferably one with each meal.

Warnings & Precautions

WARNING: Do not use this product if you are allergic to sulfur.

KEEP OUT OF REACH OF CHILDREN.

TAMPER EVIDENT Do not use if outer seal is broken or missing.

Formulation Notes

gluten free dairy free soy free nut free

Does not contain: Yeast, Corn, Wheat, Gluten, Sugar, Soy, Starch, Dairy, Citrus, Fish, Preservatives, Artificial Colors or Flavors.

Additional Information

specialty

joint

{tablet} actual size

STORE IN A COOL, DRY PLACE.

Visit www.vitaminshoppe.com or call 1-800-223-1216 for more information and to reorder.

{QRC} learn more at vsquality.net

Item No. VS-1462 1048829 CO 1

Metadata

Product Details

UPC / SKU7 66536 01462 0
DSLD Entry Date2014-07-25
Product TypeOther Combinations
FormTablet or Pill
BrandThe Vitamin Shoppe
DSLD ID35840
Data Updated2026-04-11
Research

Research Evidence

33
Research Sources
48
Avg Quality
21
Rct
10
Meta Analysis
2
Clinical Trial
B Chondroitin for osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
B Efficacy and safety of the combination of glucosamine and chondroitin for knee osteoarthritis: a systematic review and meta-analysis
Meta Analysis Archives of orthopaedic and trauma surgery 2023 PubMed DOI
B Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis
Rct The New England journal of medicine 2006 PubMed
B Clinical Efficacy and Safety of Chondroitin Combined with Glucosamine in the Treatment of Knee Osteoarthritis: A Systematic Review and Meta-Analysis
Meta Analysis Computational and mathematical methods in medicine 2022 PubMed DOI
B Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib
Rct Annals of the rheumatic diseases 2016 PubMed DOI
B Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trials
Meta Analysis Journal of orthopaedic surgery and research 2018 PubMed DOI
C Update on the role of pharmaceutical-grade chondroitin sulfate in the symptomatic management of knee osteoarthritis
Meta Analysis Aging clinical and experimental research 2019 PubMed DOI
C Evaluation of efficacy and safety of glucosamine sulfate, chondroitin sulfate, and their combination regimen in the management of knee osteoarthritis: a systematic review and meta-analysis
Meta Analysis Inflammopharmacology 2024 PubMed DOI
C Does incorporating collagen and chondroitin sulfate matrix in implant surfaces enhance osseointegration? A systematic review and meta-analysis
Meta Analysis International journal of oral and maxillofacial surgery 2018 PubMed DOI
C Effect of glucosamine and chondroitin sulfate in symptomatic knee osteoarthritis: a systematic review and meta-analysis of randomized placebo-controlled trials
Meta Analysis Rheumatology international 2018 PubMed DOI
View all evidence for Chondroitin →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.