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Cleanse Supplements

product on market Other (e.g. tea bag) Clean Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 43% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This formula contains calcium and phosphorus for structural support, alongside a phyto enzyme complex. Coptis and Oregon grape extracts provide berberine, which has moderate evidence for supporting metabolic health. Overall, the evidence coverage for this specific ingredient combination is very limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Cleanse Supplements
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Packet(s)
Serving Size
63
Servings
Botanical with Nutrients
Product Type
43%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calcium
100 mg (10% DV)
77 mg (8% DV)
Within RDA (0.1× RDA) 13 studies (A:0, B:3)
Phyto Enzyme Complex
202 mg
Coptis (Coptis chinensis) root & rhizome 12:1 extract
15 mg
Market median: 500.0mg (234 products) 95 studies (A:0, B:35)
200 mg
Market median: 500.0mg (234 products) 95 studies (A:0, B:35)
A 4:1 Proprietary Extract
150 mg

Other Ingredients

Digestive Enzyme Cleanse Berberine Formula
Claims

Label Claims — Verification

Unverified All Other
Info

Product Information

Directions for Use

Directions: Take one packet, three times a day, or as directed by your healthcare practitioner.

Warnings & Precautions

Notice: Do not use if you have or develop diarrhea, loose stools, or abdominal pain because rhubarb may worsen these conditions and be harmful to your health.

Consult your physician if you have frequent diarrhea or if taking medication including cyclosporine, or have a medical condition.

Warning: Do not use if pregnant or nursing.

Do not use if you are currently experiencing or have a history of a peptic or duodenal ulcer..

Do not use if you are on medications for bipolar disorder, active cancer or have a history with cancer. Consult your physician if you are taking medications, or have a medical condition.

Keep out of the reach of children.

Formulation Notes

Formulated to Exclude: Wheat, Dairy, Soy, Nuts, tree nuts, fish, crustacean shellfish, colors, artificial sweeteners, and preservatives.

Additional Information

Cleanse Supplements

Each Packet Contains: 1 Digestive tablet (white) and 1 Cleanse Berberine Formula tablet (dark yellow/orange).

Storage: Store in a cool, dry place.

This product is not intended to diagnose, treat, cure, or prevent any disease.

Made in the United States of America

A Lifetime of Support: We are here for you before, during, and after your cleanse. Forever. There's no expiration date on our support. cleanprogram.com/support

Metadata

Product Details

UPC / SKU7 00953 53121 6
DSLD Entry Date2014-06-25
Product TypeBotanical with Nutrients
FormOther (e.g. tea bag)
BrandClean
DSLD ID34827
Data Updated2026-04-11
Research

Research Evidence

849
Research Sources
56
Avg Quality
450
Meta Analysis
152
Rct
137
Systematic Review
73
Clinical Trial
11
Regulatory Source
7
Other
7
Guideline
3
Openfda Safety
2
Cochrane Review
2
Observational
A Phosphate binders for preventing and treating chronic kidney disease-mineral and bone disorder (CKD-MBD)
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late life
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems
Meta Analysis The Cochrane database of systematic reviews 2025 PubMed DOI
A Dietary calcium supplementation for preventing colorectal cancer and adenomatous polyps
Systematic Review The Cochrane database of systematic reviews 2008 PubMed DOI
A Calcium and vitamin D for increasing bone mineral density in premenopausal women
Systematic Review The Cochrane database of systematic reviews 2023 PubMed DOI
A Dietary sodium, sodium-to-potassium ratio, and risk of stroke: A systematic review and nonlinear dose-response meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2019 PubMed DOI
A The association between circulating magnesium and clinically relevant outcomes in patients with chronic kidney disease: A systematic review and meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2021 PubMed DOI
A Calcium channel blockers versus other classes of drugs for hypertension
Systematic Review The Cochrane database of systematic reviews 2021 PubMed DOI
View all evidence for Electrolytes →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.