Joint Rebuild

product on market Capsule Signature Supplements 🟢 Safety: 100/100
Brand: Signature Supplements
🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 50% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

2 Capsule(s) Serving Size
50 Servings
Other Combinations Product Type
50% Evidence Coverage

Supplement Facts — Evidence Check

185 mg (19% DV)
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 185mg
180 mg
📊 Market median: 1000.0mg (1115 products) 📚 22 studies (Tier A: 0, B: 9)
This product: 180mg
170 mg
📊 Market median: 1000.0mg (2 products)
This product: 170mg
120 mg
📊 Market median: 600.0mg (79 products) 📚 24 studies (Tier A: 0, B: 6)
This product: 120mg
50 mg
📊 Market median: 200.0mg (136 products) 📚 3 studies — no high-quality reviews
This product: 50mg
Papaya
50 mg

Other Ingredients

Cellulose Diatomaceous Earth

Label Claims — Verification

❓ Nutrient
❓ All Other
❓ Structure/Function
All Other (99% of products) Structure/Function (85% of products) Nutrient (54% of products) Approved Health (3% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free Dairy Free Sugar Free

Product Information

📋 Directions for Use

Directions: For adults, take two (2) capsules daily, more if needed.

⚠️ Warnings & Precautions

Keep out of reach of children store in a dry place and avoid excessive heat.

As a reminder, discuss the supplements and medications you take with your health care providers.

🧪 Formulation Notes

No: chemical fillers or binders, artificial coloring, artificial flavor, preservatives, yeast, corn, milk or milk derivatives, lactose, salt, sodium, soy, sugar, gluten, starch or wheat.

From a GMP facility

Powerful nutritional joint support Joint Rebuild incorporates the latest clinical research with additional joint supporting nutrients.

The well-known ingredients of glucosamine & chondroitin are included in this formula at levels to support joint health.

This product contains 185 mg of elemental calcium per serving counted towards your daily calcium needs.

Additional Information

Keep out of reach of children store in a dry place and avoid excessive heat.

Product Details

DSLD Entry Date 2025-08-22
Product Type Other Combinations
Form Capsule
Brand Signature Supplements
DSLD ID 338798
Data Updated 2026-04-11

Research Evidence

849 Research Sources
56 Avg Quality Score
450 Meta Analysis
152 Rct
137 Systematic Review
73 Clinical Trial
11 Regulatory Source
7 Other
7 Guideline
3 Openfda Safety
2 Cochrane Review
2 Observational
A Phosphate binders for preventing and treating chronic kidney disease-mineral and bone disorder (CKD-MBD)
Meta Analysis The Cochrane database of systematic reviews 2018
PubMed DOI Cochrane
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2024
PubMed DOI Cochrane
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2015
PubMed DOI Cochrane
A Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late life
Meta Analysis The Cochrane database of systematic reviews 2018
PubMed DOI Cochrane
A Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems
Meta Analysis The Cochrane database of systematic reviews 2025
PubMed DOI Cochrane
A Dietary calcium supplementation for preventing colorectal cancer and adenomatous polyps
Systematic Review The Cochrane database of systematic reviews 2008
PubMed DOI Cochrane
A Calcium and vitamin D for increasing bone mineral density in premenopausal women
Systematic Review The Cochrane database of systematic reviews 2023
PubMed DOI Cochrane
A Dietary sodium, sodium-to-potassium ratio, and risk of stroke: A systematic review and nonlinear dose-response meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2019
PubMed DOI
A The association between circulating magnesium and clinically relevant outcomes in patients with chronic kidney disease: A systematic review and meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2021
PubMed DOI
A Calcium channel blockers versus other classes of drugs for hypertension
Systematic Review The Cochrane database of systematic reviews 2021
PubMed DOI
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