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Joint Rebuild

product on market Capsule Signature Supplements Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 50% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

Glucosamine, chondroitin, and MSM are supported by moderate evidence for managing joint discomfort and supporting cartilage health. Bromelain and coral calcium may provide additional anti-inflammatory and structural support, though evidence for these specific forms is more limited. Overall, the ingredient profile focuses on established compounds for joint maintenance.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Joint Rebuild
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Capsule(s)
Serving Size
50
Servings
Other Combinations
Product Type
50%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

185 mg (19% DV)
Market median: 4002.0mg (1 products) 21 studies (A:0, B:2)
Market median: 1000.0mg (1115 products) 24 studies (A:0, B:9)
Market median: 1000.0mg (2 products)
Market median: 600.0mg (79 products) 25 studies (A:0, B:6)
50 mg
Market median: 200.0mg (136 products) 3 studies — no high-quality reviews
Papaya
50 mg

Other Ingredients

Cellulose Diatomaceous Earth
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: For adults, take two (2) capsules daily, more if needed.

Warnings & Precautions

Keep out of reach of children store in a dry place and avoid excessive heat.

As a reminder, discuss the supplements and medications you take with your health care providers.

Formulation Notes

No: chemical fillers or binders, artificial coloring, artificial flavor, preservatives, yeast, corn, milk or milk derivatives, lactose, salt, sodium, soy, sugar, gluten, starch or wheat.

From a GMP facility

Powerful nutritional joint support Joint Rebuild incorporates the latest clinical research with additional joint supporting nutrients.

The well-known ingredients of glucosamine & chondroitin are included in this formula at levels to support joint health.

This product contains 185 mg of elemental calcium per serving counted towards your daily calcium needs.

Additional Information

Keep out of reach of children store in a dry place and avoid excessive heat.

Metadata

Product Details

DSLD Entry Date2025-08-22
Product TypeOther Combinations
FormCapsule
BrandSignature Supplements
DSLD ID338798
Data Updated2026-04-11
Research

Research Evidence

849
Research Sources
56
Avg Quality
450
Meta Analysis
152
Rct
137
Systematic Review
73
Clinical Trial
11
Regulatory Source
7
Other
7
Guideline
3
Openfda Safety
2
Cochrane Review
2
Observational
A Phosphate binders for preventing and treating chronic kidney disease-mineral and bone disorder (CKD-MBD)
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late life
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems
Meta Analysis The Cochrane database of systematic reviews 2025 PubMed DOI
A Dietary calcium supplementation for preventing colorectal cancer and adenomatous polyps
Systematic Review The Cochrane database of systematic reviews 2008 PubMed DOI
A Calcium and vitamin D for increasing bone mineral density in premenopausal women
Systematic Review The Cochrane database of systematic reviews 2023 PubMed DOI
A Dietary sodium, sodium-to-potassium ratio, and risk of stroke: A systematic review and nonlinear dose-response meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2019 PubMed DOI
A The association between circulating magnesium and clinically relevant outcomes in patients with chronic kidney disease: A systematic review and meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2021 PubMed DOI
A Calcium channel blockers versus other classes of drugs for hypertension
Systematic Review The Cochrane database of systematic reviews 2021 PubMed DOI
View all evidence for Electrolytes →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.