Liquid Glucosamine & Chondroitin with MSM by NOW — Ingredients, Evidence & Safety

Product Label

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Label Data

15 mL Serving Size

63 Servings

Other Combinations Product Type

25% Evidence Coverage

Supplement Facts — Evidence Check

Calories

15 Calorie(s)

Total Carbohydrates

4 Gram(s) (1% DV)

Vitamin C

100 mg (111% DV)

Manganese

4 mg (174% DV)

✅ 1.7× RDA — within safe limits 📚 8 studies — no high-quality reviews

RDA 2.3mg This product: 4mg UL 11mg

Sodium

70 mg (3% DV)

Glucosamine HCl

750 mg

📊 Market median: 1000.0mg (1115 products) 📚 22 studies (Tier A: 0, B: 9)

This product: 750mg

Chondroitin Sodium Sulfate

600 mg

📊 Market median: 600.0mg (79 products) 📚 24 studies (Tier A: 0, B: 6)

This product: 600mg

Methylsulfonylmethane

150 mg

📊 Market median: 1000.0mg (2 products)

This product: 150mg

Other Ingredients

Water, Deionized Glycerin Fructose Natural Flavors Malic Acid Citric Acid Xanthan Gum Potassium Sorbate Beta-Carotene, Natural

Label Claims — Verification

❓ Nutrient

❓ All Other

❓ Structure/Function

All Other (100% of products) Structure/Function (89% of products) Nutrient (16% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free Dairy Free

Product Information

📋 Directions for Use

Suggested Usage: Take 1 tablespoon (15 mL) twice daily. Shake well before use.

⚠️ Warnings & Precautions

Caution: Persons with a known allergy to shellfish should not use this product.

For adults only.

Consult physician if pregnant/nursing, taking medication, or have a medical condition (especially glaucoma).

Keep out of reach of children.

Contains shellfish (shrimp, crab). Natural Beta-Carotene contains refined soy oil.

Not manufactured with wheat, gluten, milk, egg, fish or sesame ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

🧪 Formulation Notes

NOW Liquid Glucosamine & Chondroitin with MSM combines three of the best known nutrients available for the support of healthy joints in a convenient liquid form. Scientific studies have demonstrated that Glucosamine and Chondroitin can promote normal joint mobility and comfort. MSM is present as a naturally occurring sulfur compound and Manganese and Vitamin C have been included as complementary ingredients to provide optimal nutritional support for the production of healthy joint structures.

Natural color variation may occur in this product.

Joint health Joint mobility and comfort Great citrus taste

Not manufactured with wheat, gluten, milk, egg, fish or sesame ingredients.

Made and quality tested in the USA with globally sourced ingredients.

Additional Information

Refrigerate after opening to preserve flavor.

General Health Family owned since 1968.

NOW Foods developed the glucosamine test method chosen as the official AOACI industry standard method.

GMP Quality Assured

Product Details

UPC / SKU 7 33739 03177 8

DSLD Entry Date 2025-09-25

Product Type Other Combinations

Form Liquid

Brand NOW

DSLD ID 335266

Data Updated 2026-04-11

Research Evidence

39 Research Sources

50 Avg Quality Score

20 Rct

9 Meta Analysis

4 Clinical Trial

3 Systematic Review

1 Regulatory Source

1 Openfda Safety

B Interventions for the management of temporomandibular joint osteoarthritis

Systematic Review The Cochrane database of systematic reviews 2012

PubMed DOI Cochrane

B Glucosamine therapy for treating osteoarthritis

Meta Analysis The Cochrane database of systematic reviews 2005

PubMed Cochrane

B Chondroitin for osteoarthritis

Meta Analysis The Cochrane database of systematic reviews 2015

PubMed DOI Cochrane

B Efficacy and safety of the combination of glucosamine and chondroitin for knee osteoarthritis: a systematic review and meta-analysis

Meta Analysis Archives of orthopaedic and trauma surgery 2023

PubMed DOI

B Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis

Rct The New England journal of medicine 2006

PubMed

B Oral Glucosamine in the Treatment of Temporomandibular Joint Osteoarthritis: A Systematic Review

Systematic Review International journal of molecular sciences 2023

PubMed DOI

B Scientific Opinion on glucosamine and joint health

Regulatory Source EFSA Journal 2009

DOI

B Clinical Efficacy and Safety of Chondroitin Combined with Glucosamine in the Treatment of Knee Osteoarthritis: A Systematic Review and Meta-Analysis

Meta Analysis Computational and mathematical methods in medicine 2022

PubMed DOI

B Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib

Rct Annals of the rheumatic diseases 2016

PubMed DOI

B Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trials

Meta Analysis Journal of orthopaedic surgery and research 2018

PubMed DOI

View all evidence for Glucosamine →