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Glucosamine & MSM

product on market Capsule NOW Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 67% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Glucosamine and chondroitin are researched for supporting joint cartilage and structure, while MSM is used to address inflammation. Clinical evidence for these ingredients is generally moderate to limited, showing varying results in joint health outcomes. These components are typically well-tolerated with a high safety profile.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Glucosamine & MSM
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Capsule(s)
Serving Size
30
Servings
Non-Nutrient/Non-Botanical
Product Type
67%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

1.1 Gram(s)
Market median: 1000.0mg (1115 products) 24 studies (A:0, B:9)
Market median: 1000.0mg (2 products)
Market median: 600.0mg (79 products) 25 studies (A:0, B:6)

Other Ingredients

Hypromellose Stearic Acid Magnesium Stearate
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested Usage: Take 2 capsules 1 to 2 times daily.

Warnings & Precautions

Caution: Persons with a known allergy to shellfish should not use this product.

Consult physician if pregnant/nursing, taking medication, or have a medical condition (especially glaucoma).

Keep out of reach of children.

Contains shellfish (shrimp, crab).

Not manufactured with wheat, gluten, soy, corn, milk, egg, fish, tree nut or sesame ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

Formulation Notes

NOW Glucosamine & MSM with Chondroitin Sulfate combines three well-known joint support ingredients. Glucosamine is an essential building block for the formation of glycosaminoglycans (GAGs) and proteoglycans, the main components of cartilage tissue. These compounds promote water retention within the joint, giving it resiliency by acting as a lubricant and a means to absorb shock. MSM (Methylsulfonylmethane) is an organic form of sulfur, a mineral necessary for the production of GAGS and proteoglycans.

Natural color variation may occur in this product.

Joint Health Supports Healthy Joint Function

Glucosamine & MSM Plus Chondroitin Sulfate

Non-GMO

Made and quality tested in the USA with globally sourced ingredients.

Not manufactured with wheat, gluten, soy, corn, milk, egg, fish, tree nut or sesame ingredients.

NOW Foods developed the glucosamine test method chosen as the official AOACI industry standard method.

Additional Information

This bottle is made from 100% PCR (postconsumer recycled) resin.

GMP Quality Assured

General Health Family owned since 1968.

Store in a cool, dry place after opening.

Metadata

Product Details

UPC / SKU7 33739 03278 2
DSLD Entry Date2025-09-25
Product TypeNon-Nutrient/Non-Botanical
FormCapsule
BrandNOW
DSLD ID335241
Data Updated2026-04-11
Research

Research Evidence

39
Research Sources
50
Avg Quality
20
Rct
9
Meta Analysis
4
Clinical Trial
3
Systematic Review
1
Regulatory Source
1
Openfda Safety
B Interventions for the management of temporomandibular joint osteoarthritis
Systematic Review The Cochrane database of systematic reviews 2012 PubMed DOI
B Glucosamine therapy for treating osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2005 PubMed
B Chondroitin for osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
B Efficacy and safety of the combination of glucosamine and chondroitin for knee osteoarthritis: a systematic review and meta-analysis
Meta Analysis Archives of orthopaedic and trauma surgery 2023 PubMed DOI
B Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis
Rct The New England journal of medicine 2006 PubMed
B Oral Glucosamine in the Treatment of Temporomandibular Joint Osteoarthritis: A Systematic Review
Systematic Review International journal of molecular sciences 2023 PubMed DOI
B Scientific Opinion on glucosamine and joint health
Regulatory Source EFSA Journal 2009 DOI
B Clinical Efficacy and Safety of Chondroitin Combined with Glucosamine in the Treatment of Knee Osteoarthritis: A Systematic Review and Meta-Analysis
Meta Analysis Computational and mathematical methods in medicine 2022 PubMed DOI
B Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib
Rct Annals of the rheumatic diseases 2016 PubMed DOI
B Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trials
Meta Analysis Journal of orthopaedic surgery and research 2018 PubMed DOI
View all evidence for Glucosamine →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.