Home/ Supplements/ Glucosamine/ Glucosamine, Chondroitin & MSM

Glucosamine, Chondroitin & MSM

product on market Tablet or Pill Natrol Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 50% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

Glucosamine and chondroitin are commonly used to support joint health, though clinical evidence for their efficacy remains moderate and mixed. MSM is often included to help manage inflammation and joint discomfort. Research suggests these ingredients are generally well-tolerated, though individual responses to joint supplements vary.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Glucosamine, Chondroitin & MSM
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Tablet(s)
Serving Size
150
Servings
Other Combinations
Product Type
50%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Sodium
28 mg (1% DV)
Market median: 1000.0mg (1115 products) 24 studies (A:0, B:9)
Market median: 600.0mg (79 products) 25 studies (A:0, B:6)
Market median: 1000.0mg (2 products)

Other Ingredients

Microcrystalline Cellulose Stearic Acid Povidone Cellulose Gum Glycerin Magnesium Stearate Methylcellulose Silicon Dioxide
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested use: Adults, take 1 tablet three times daily, with a meal.

Warnings & Precautions

Warning: Consult a healthcare professional before using this product if you are pregnant, nursing, under the age of 18, are taking medication or have a medical condition; if adverse reactions occur, discontinue use.

Warning: Consult a healthcare professional before using this product if you are pregnant, nursing, under the age of 18, are taking medication or have a medical condition; if adverse reactions occur, discontinue use. Keep out of reach of children.

Contains: crustacean shellfish (crab and shrimp)

Do not use if safety seal is damaged or missing.

Formulation Notes

Natrol Glucosamine, Chondroitin & MSM: Nutrient support for joint health Glucosamine supports healthy joint cartilage Chondroitin provides substrates for lubricating [synovial] fluids for the joints MSM supports joint health

Joint health Nutrient support for joint health Supports joint flexibility & lubrication

100% Drug free

No: milk, egg, fish, tree nuts, peanuts, wheat, soybeans, sesame

Additional Information

Store in a cool, dry place.

Metadata

Product Details

UPC / SKU0 47469 00224 4
DSLD Entry Date2025-05-21
Product TypeOther Combinations
FormTablet or Pill
BrandNatrol
DSLD ID332989
Data Updated2026-04-11
Research

Research Evidence

39
Research Sources
50
Avg Quality
20
Rct
9
Meta Analysis
4
Clinical Trial
3
Systematic Review
1
Regulatory Source
1
Openfda Safety
B Interventions for the management of temporomandibular joint osteoarthritis
Systematic Review The Cochrane database of systematic reviews 2012 PubMed DOI
B Glucosamine therapy for treating osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2005 PubMed
B Chondroitin for osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
B Efficacy and safety of the combination of glucosamine and chondroitin for knee osteoarthritis: a systematic review and meta-analysis
Meta Analysis Archives of orthopaedic and trauma surgery 2023 PubMed DOI
B Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis
Rct The New England journal of medicine 2006 PubMed
B Oral Glucosamine in the Treatment of Temporomandibular Joint Osteoarthritis: A Systematic Review
Systematic Review International journal of molecular sciences 2023 PubMed DOI
B Scientific Opinion on glucosamine and joint health
Regulatory Source EFSA Journal 2009 DOI
B Clinical Efficacy and Safety of Chondroitin Combined with Glucosamine in the Treatment of Knee Osteoarthritis: A Systematic Review and Meta-Analysis
Meta Analysis Computational and mathematical methods in medicine 2022 PubMed DOI
B Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib
Rct Annals of the rheumatic diseases 2016 PubMed DOI
B Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trials
Meta Analysis Journal of orthopaedic surgery and research 2018 PubMed DOI
View all evidence for Glucosamine →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.