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Folic Acid

product on market Powder BulkSupplements.com Safety: 60/100
60/100

Review before taking

  • Folic Acid: 800mg is 800.0× the Tolerable Upper Intake Level (1.0mg)
  • 100% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Folic acid is a synthetic form of folate with strong evidence for preventing neural tube defects during pregnancy. While widely researched, the low safety score suggests potential concerns regarding long-term high-dose supplementation or masking vitamin B12 deficiency. Users should be aware of these risks when considering supplementation.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Folic Acid: 800mg is 800.0× the Tolerable Upper Intake Level (1.0mg)

AI-generated · Qwen 3.6 · grounded in 2 sources · methodology

This product received a low safety score because the amount of folic acid exceeds the recommended daily upper limit. Specifically, it contains 800 times the maximum suggested intake level.

Label

Product Label

Label for Folic Acid
Open Full PDF View on NIH DSLD →
Details

Label Data

480 Microgram(s)
Serving Size
520833
Servings
Vitamin
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

800 mcg DFE (200% DV)
Exceeds UL by 800.0× (UL: 1.0 mg) 226 studies (A:10, B:105)
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested Use: As a dietary supplement, take 480 mcg once daily, or as directed by a physician.

Warnings & Precautions

Always consult a physician before taking any dietary supplement.

Keep out of reach of children.

Formulation Notes

Folic Acid 480 mcg per serving Vitamin B9

Free of: Soy, dairy, yeast, gluten, sugars, additives

Additional Information

Use an accurate milligram scale. New

Contents are sold by weight, not volume. Settling may occur. Store in a dry, cool, dark place.

Metadata

Product Details

UPC / SKUX000V15MD9
DSLD Entry Date2025-04-24
Product TypeVitamin
FormPowder
DSLD ID330925
Data Updated2026-04-11
Research

Research Evidence

363
Research Sources
57
Avg Quality
187
Meta Analysis
56
Systematic Review
54
Rct
29
Guideline
26
Clinical Trial
6
Cochrane Review
2
Regulatory Source
1
Other
1
Openfda Safety
A Homocysteine-lowering interventions for preventing cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Community-based intervention packages for reducing maternal and neonatal morbidity and mortality and improving neonatal outcomes
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Folate Intake and Risk of Pancreatic Cancer: A Systematic Review and Updated Meta-Analysis of Epidemiological Studies
Meta Analysis Digestive diseases and sciences 2021 PubMed DOI
A The Association Between the Risk of Hypertensive Disorders of Pregnancy and Folic Acid: A Systematic Review and Meta-Analysis
Meta Analysis Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 2021 PubMed DOI
A A Comparative Study Evaluating the Effectiveness of Folate-Based B Vitamin Intervention on Cognitive Function of Older Adults under Mandatory Folic Acid Fortification Policy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Meta Analysis Nutrients 2024 PubMed DOI
A Associations between serum Homocysteine, vitamin B9, and vitamin B12 levels and the formation of intracranial Aneurysms: A systematic review and meta-analysis
Meta Analysis Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2025 PubMed DOI
A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
Meta Analysis Critical reviews in food science and nutrition 2019 PubMed DOI
A Beneficial effects of folic acid supplementation on lipid markers in adults: A GRADE-assessed systematic review and dose-response meta-analysis of data from 21,787 participants in 34 randomized controlled trials
Meta Analysis Critical reviews in food science and nutrition 2022 PubMed DOI
A Folic acid supplementation and blood pressure: a GRADE-assessed systematic review and dose-response meta-analysis of 41,633 participants
Meta Analysis Critical reviews in food science and nutrition 2023 PubMed DOI
A Digital tracking, provider decision support systems, and targeted client communication via mobile devices to improve primary health care
Meta Analysis The Cochrane database of systematic reviews 2025 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.