🟢 90/100

This product looks safe

  • Contains proprietary blend — exact ingredient amounts not disclosed
  • 60% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Safety Alerts

ℹ️ Contains proprietary blend — exact ingredient amounts not disclosed

Label Data

2 Capsule(s) Serving Size
240 Servings
Other Combinations Product Type
60% Evidence Coverage

Supplement Facts — Evidence Check

300 mg
📊 Market median: 250.0mg (562 products) 📚 53 studies (Tier A: 0, B: 19)
This product: 300mg
100 mg
📊 Market median: 500.0mg (180 products) 📚 5 studies (Tier A: 0, B: 1)
This product: 100mg
N-Acetyl-Cysteine
75 mg
200 mcg
📊 3.6× RDA — above typical dose (UL: 0.4 mg) 📚 172 studies (Tier A: 0, B: 67)
RDA 0.055mg This product: 0.2mg UL 0.4mg
Proprietary Blend
350 mg

Label Claims — Verification

All Other
All Other (99% of products) Structure/Function (83% of products) Nutrient (4% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

DIRECTIONS: Take two capsules daily with water as a dietary supplement or as directed by your physician.

⚠️ Warnings & Precautions

PLEASE KEEP OUT OF REACH OF CHILDREN

If you are pregnant, lactating, or taking prescription medications please consult your physician before taking this product.

Do not use if safety seal is broken or missing.

🧪 Formulation Notes

FREE OF: Artificial Colors, Flavors or Preservatives

Additional Information

Ultimate Liver Plus was developed by Dr. Stan Guberman for his patients. Presently, liver supplements on the market today do not have enough ingredients that specifically affect the liver. Now the Ultimate Liver Plus has over twelve ingredients specifically focused on liver health. Plus, the Ultimate Liver Plus has the highest potency of silimarin per capsule of any supplement on the market today.

Processed under the highest standard of quality assurance and Good Manufacturing Practices.

LABORATORY TESTED AND GUARANTEED

Store tightly closed in a dry place at a controlled temperature of 59(0)-86(0)F (15(0)-30(0)C)

Product Details

DSLD Entry Date 2014-05-23
Product Type Other Combinations
Form Capsule
DSLD ID 33062
Data Updated 2026-04-11

Research Evidence

69 Research Sources
55 Avg Quality Score
34 Meta Analysis
26 Systematic Review
5 Rct
3 Clinical Trial
1 Openfda Safety
A Silymarin for adults with metabolic dysfunction-associated steatotic liver disease
Meta Analysis The Cochrane database of systematic reviews 2025
B Evaluation of the effect of herbal agents as management of radiodermatitis in breast cancer patients: A systematic review and meta-analysis
Meta Analysis Japan journal of nursing science : JJNS 2024
B Efficacy of different interventions for nonalcoholic fatty liver disease: A meta-analysis of lifestyle modifications, silymarin, and medications
Meta Analysis Asia Pacific journal of clinical nutrition 2025
B Milk thistle for alcoholic and/or hepatitis B or C virus liver diseases
Meta Analysis The Cochrane database of systematic reviews 2007
B Pharmacotherapy for trichotillomania
Meta Analysis The Cochrane database of systematic reviews 2021
B Effects berberine-silymarin on liver enzymes: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition ESPEN 2022
B Efficacy of traditional Chinese medicine combined with Silibinin on nonalcoholic fatty liver disease: A meta-analysis and systematic review
Meta Analysis Medicine 2024
B Are alterations needed in Silybum marianum (Silymarin) administration practices? A novel outlook and meta-analysis on randomized trials targeting liver injury
Meta Analysis BMC complementary medicine and therapies 2025
B The therapeutic effects of silymarin for patients with glucose/lipid metabolic dysfunction: A meta-analysis
Meta Analysis Medicine 2020
B Administration of silymarin in NAFLD/NASH: A systematic review and meta-analysis
Meta Analysis Annals of hepatology 2024
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