100/100

This product looks safe

No ingredients exceed tolerable upper intake levels
Limited research evidence available for ingredients

B Label Compliance Grade

Label

Product Label

Open Full PDF View on NIH DSLD →

Details

Label Data

1 Vegetarian Capsule(s)

Serving Size

Servings

Other Combinations

Product Type

Evidence Coverage

Ingredients

Supplement Facts — Evidence Check

Sodium

28 mg (1% DV)

Bio-Enhanced

283 mg

Other Ingredients

Cellulose Stearate Silica

Claims

Label Claims — Verification

Unverified All Other

Info

Product Information

Directions for Use

Directions: Take one (1) to two (2) capsules daily as tolerated, preferably on an empty stomach or as recommended by a healthcare practitioner.

Warnings & Precautions

Read the entire label and follow the directions carefully.

Warnings: Keep out of reach of children.

Do not exceed recommended dose. Do not purchase if outer seal is damaged.

Consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

To report a serious adverse event or obtain product information, contact 1-866-280-2852.

Formulation Notes

Gluten free Non GMO LE Certified

Bio-Enhanced active form of lipoic acid

Additional Information

Scan for product info

Non GMO LE Certified

Store tightly closed in a cool, dry place.

Metadata

Product Details

UPC / SKU7 37870 12086 5

DSLD Entry Date2025-05-21

Product TypeOther Combinations

FormCapsule

BrandLife Extension

DSLD ID328720

Data Updated2026-04-11

Research

Research Evidence

Research Sources

Avg Quality

Rct

Meta Analysis

Systematic Review

Clinical Trial

A Alpha-lipoic acid for diabetic peripheral neuropathy

Systematic Review The Cochrane database of systematic reviews 2024 PubMed DOI

B Efficacy and Safety of the Combination of Palmitoylethanolamide, Superoxide Dismutase, Alpha Lipoic Acid, Vitamins B12, B1, B6, E, Mg, Zn and Nicotinamide for 6 Months in People with Diabetic Neuropathy

Rct Nutrients 2024 PubMed DOI

B Alpha Lipoic Acid Supplementation and Iron Homeostasis: A Comprehensive Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials

Meta Analysis International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 2024 PubMed DOI

B Effectiveness of alpha-lipoic acid in patients with neuropathic pain associated with type I and type II diabetes mellitus: A systematic review and meta-analysis

Meta Analysis Medicine 2023 PubMed DOI

C The effects of alpha-lipoic acid supplementation on glucose control and lipid profiles among patients with metabolic diseases: A systematic review and meta-analysis of randomized controlled trials

Meta Analysis Metabolism: clinical and experimental 2018 PubMed DOI

C A systematic review and meta-analysis of α-lipoic acid in the treatment of diabetic peripheral neuropathy

Meta Analysis European journal of endocrinology 2012 PubMed DOI

C Oral Alpha Lipoic Acid Treatment for Symptomatic Diabetic Peripheral Neuropathy: A Randomized Double-Blinded Placebo-Controlled Study

Rct Endocrine, metabolic & immune disorders drug targets 2020 PubMed DOI

C A randomized, double-blind, placebo controlled study to evaluate the effect of alpha-lipoic acid on inhibition of ADP-and collagen-induced platelet aggregation ex vivo in diabetic neuropathy patients on gabapentin or pregabalin

Rct Journal of postgraduate medicine 2024 PubMed DOI

C Ranking Alpha Lipoic Acid and Gamma Linolenic Acid in Terms of Efficacy and Safety in the Management of Adults With Diabetic Peripheral Neuropathy: A Systematic Review and Network Meta-analysis

Systematic Review Canadian journal of diabetes 2024 PubMed DOI

C Effect analysis of tanshinone IIA sulfonate sodium combined with a-lipoic acid in patients with diabetes peripheral neuropathy.

Rct Pakistan journal of pharmaceutical sciences PubMed

View all evidence for Alpha Lipoic Acid →

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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.