HepatoPro by Life Extension — Ingredients, Evidence & Safety

🟢 100/100

This product looks safe

No ingredients exceed tolerable upper intake levels
33% of ingredients have research evidence

A Label Compliance Grade

Product Label

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Label Data

1 Softgel(s) Serving Size

60 Servings

Fat/Fatty Acid Product Type

33% Evidence Coverage

Supplement Facts — Evidence Check

Calories

10 Calorie(s)

Total Fat

1 Gram(s) (1% DV)

Polyenylphosphatidylcholine

900 mg

✅ 1.6× RDA — within safe limits 📚 36 studies (Tier A: 1, B: 7)

RDA 550mg This product: 900mg UL 3500mg

Other Ingredients

Gelatin Medium Chain Triglyceride Sorbitol Glycerin Ethanol Water, Purified Silica

Label Claims — Verification

❓ Nutrient

❓ All Other

❓ Structure/Function

All Other (97% of products) Structure/Function (90% of products) Nutrient (42% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

Directions: Take one (1) softgel two to three times daily, or as recommended by a healthcare practitioner.

⚠️ Warnings & Precautions

Read the entire label and follow the directions carefully prior to use.

Warnings: Keep out of reach of children.

Do not exceed recommended dose. Do not purchase if outer seal is broken or damaged.

When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

Contains soybeans.

To report a serious adverse event or obtain product information, contact 1-866-280-2852.

🧪 Formulation Notes

Polyunsaturated phosphatidylcholine 900 mg

Gluten free Non GMO LE Certified

Supports a healthy liver

Additional Information

Scan for product info

Protect from heat and light.

Non GMO LE Certified

Store tightly closed in a cool, dry place.

Product Details

UPC / SKU 7 37870 13936 2

DSLD Entry Date 2025-04-24

Product Type Fat/Fatty Acid

Form Softgel Capsule

Brand Life Extension

DSLD ID 328474

Data Updated 2026-04-11

Research Evidence

28 Research Sources

47 Avg Quality Score

11 Clinical Trial

8 Rct

2 Guideline

2 Meta Analysis

2 Regulatory Source

1 Systematic Review

1 Openfda Safety

B Greater Choline-Containing Compounds and Myo-inositol in Treatment-Resistant Versus Responsive Schizophrenia: A 1H-Magnetic Resonance Spectroscopy Meta-analysis

Meta Analysis Biological psychiatry. Cognitive neuroscience and neuroimaging 2024

PubMed DOI

B Integrating multi-structure covalent docking with machine-learning consensus scoring enhances potency ranking of human acetylcholinesterase inhibitors.

Guideline Briefings in bioinformatics 2026

PubMed DOI

B Evidence-based clinical practice guidelines for functional dyspepsia 2021.

Guideline Journal of gastroenterology 2022

PubMed DOI

B Scientific Opinion on health claims related to choline

Regulatory Source EFSA Journal 2011

DOI

C Effectiveness of nutritional interventions to prevent nonprogressive congenital and perinatal brain injuries: a systematic review and meta-analysis of randomized trials

Meta Analysis Nutrition reviews 2022

PubMed DOI

C Two methods for assessment of choline status in a randomized crossover study with varying dietary choline intake in people: isotope dilution MS of plasma and in vivo single-voxel magnetic resonance spectroscopy of liver.

Rct The American journal of clinical nutrition

PubMed DOI

C Choline and betaine concentrations in plasma discriminate levels of dietary choline intake in healthy adults: analysis of a double-blind randomized crossover controlled feeding study.

Rct The American journal of clinical nutrition

PubMed DOI

C Nutrient-based therapies for bipolar disorder: a systematic review

Systematic Review Psychotherapy and psychosomatics 2013

PubMed DOI

C The association of betaine, homocysteine and related metabolites with cognitive function in Dutch elderly people

Rct The British journal of nutrition 2007

PubMed

C Differential metabolism of choline supplements in adult volunteers.

Rct European journal of nutrition

PubMed DOI

View all evidence for Choline →