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Methylation Complete Pro

product on market Tablet or Pill NBX Wellness Safety: 87/100
87/100

This product is generally safe

  • Folate: 5440mg is 5440.0× the Tolerable Upper Intake Level (1.0mg)
  • 100% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Vitamin B6, folate, and B12 are essential nutrients that support methylation processes and homocysteine regulation. There is strong evidence for their role in neurological function and cellular metabolism. However, overall evidence coverage for this specific formulation is limited.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Folate: 5440mg is 5440.0× the Tolerable Upper Intake Level (1.0mg)

Label

Product Label

Label for Methylation Complete Pro
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Tablet(s)
Serving Size
66
Servings
Vitamin
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

2 mg (118% DV)
1.5× RDA — within safe limits 114 studies (A:3, B:35)
5440 mcg DFE (1360% DV)
Exceeds UL by 5440.0× (UL: 1.0 mg) 226 studies (A:10, B:105)
7000 mcg (291667% DV)
2916.7× RDA — above typical dose 139 studies (A:1, B:44)

Other Ingredients

Sorbitol Mannitol natural Fruit Punch flavor Croscarmellose Sodium Stearic Acid Silicon Dioxide Ascorbyl Palmitate
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested use: Place one tablet in the mouth twice daily. Allow 1-3 minutes for tablet to dissolve, then swallow as needed.

Warnings & Precautions

Caution: Keep out of reach of children. Consult your healthcare provider on proper dosage for children under 5 years of age.

If you are pregnant or nursing, please consult with your healthcare provider.

Formulation Notes

Exclusive Supports: Methylation-related genes

Enhanced B-vitamin delivery

Gluten free Non-GMO

Complete Bioactive Professional Grade

B-Vitamins Support

Additional Information

GMP Certified

Storage: Keep tightly closed in a cool, dry place. Avoid direct sunlight.

Metadata

Product Details

UPC / SKU8 50045 01211 3
DSLD Entry Date2025-02-23
Product TypeVitamin
FormTablet or Pill
BrandNBX Wellness
DSLD ID327688
Data Updated2026-04-11
Research

Research Evidence

153
Research Sources
55
Avg Quality
71
Systematic Review
51
Meta Analysis
19
Rct
6
Clinical Trial
2
Other
2
Regulatory Source
1
Openfda Safety
A Efficacy of vitamin and antioxidant supplements in prevention of cardiovascular disease: systematic review and meta-analysis of randomised controlled trials
Meta Analysis BMJ (Clinical research ed.) 2013 PubMed DOI
A Homocysteine lowering interventions for preventing cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2009 PubMed DOI
A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
Meta Analysis Critical reviews in food science and nutrition 2019 PubMed DOI
A Exploring the causal associations of micronutrients on urate levels and the risk of gout: A Mendelian randomization study
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
A Pyridoxine (vitamin B6) supplementation during pregnancy or labour for maternal and neonatal outcomes
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
B Prophylactic drug management for febrile seizures in children
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
B Treatments for Hyperemesis Gravidarum and Nausea and Vomiting in Pregnancy: A Systematic Review
Systematic Review JAMA 2016 PubMed DOI
B The potential role of nutritional components in improving brain function among patients with Alzheimers disease: a meta-analysis of RCT studies
Meta Analysis Neurosciences (Riyadh, Saudi Arabia) 2020 PubMed DOI
B Pyridoxine (vitamin B6) supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2006 PubMed
B Effect of ginger in the treatment of nausea and vomiting compared with vitamin B6 and placebo during pregnancy: a meta-analysis
Meta Analysis The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2022 PubMed DOI
View all evidence for Vitamin B6 →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.