🟢 87/100

This product is generally safe

  • Folate: 5440mg is 5440.0× the Tolerable Upper Intake Level (1.0mg)
  • 100% of ingredients have research evidence
C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Folate: 5440mg is 5440.0× the Tolerable Upper Intake Level (1.0mg)

Label Data

1 Tablet(s) Serving Size
66 Servings
Vitamin Product Type
100% Evidence Coverage

Supplement Facts — Evidence Check

2 mg (118% DV)
✅ 1.5× RDA — within safe limits 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 2mg UL 100mg
5440 mcg DFE (1360% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 5440.0× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 5440mg UL 1.0mg
7000 mcg (291667% DV)
📊 2916.7× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 7.0mg

Other Ingredients

Sorbitol Mannitol natural Fruit Punch flavor Croscarmellose Sodium Stearic Acid Silicon Dioxide Ascorbyl Palmitate

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (98% of products) Structure/Function (89% of products) Nutrient (43% of products)

Target Groups

Children 4 or More Years of Age Adult (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

Suggested use: Place one tablet in the mouth twice daily. Allow 1-3 minutes for tablet to dissolve, then swallow as needed.

⚠️ Warnings & Precautions

Caution: Keep out of reach of children. Consult your healthcare provider on proper dosage for children under 5 years of age.

If you are pregnant or nursing, please consult with your healthcare provider.

🧪 Formulation Notes

Exclusive Supports: Methylation-related genes

Enhanced B-vitamin delivery

Gluten free Non-GMO

Complete Bioactive Professional Grade

B-Vitamins Support

Additional Information

GMP Certified

Storage: Keep tightly closed in a cool, dry place. Avoid direct sunlight.

Product Details

UPC / SKU 8 50045 01211 3
DSLD Entry Date 2025-02-23
Product Type Vitamin
Form Tablet or Pill
Brand NBX Wellness
DSLD ID 327688
Data Updated 2026-04-11

Research Evidence

153 Research Sources
55 Avg Quality Score
71 Systematic Review
51 Meta Analysis
19 Rct
6 Clinical Trial
2 Other
2 Regulatory Source
1 Openfda Safety
A Efficacy of vitamin and antioxidant supplements in prevention of cardiovascular disease: systematic review and meta-analysis of randomised controlled trials
Meta Analysis BMJ (Clinical research ed.) 2013
A Homocysteine lowering interventions for preventing cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2009
A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
Meta Analysis Critical reviews in food science and nutrition 2019
A Exploring the causal associations of micronutrients on urate levels and the risk of gout: A Mendelian randomization study
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024
A Pyridoxine (vitamin B6) supplementation during pregnancy or labour for maternal and neonatal outcomes
Meta Analysis The Cochrane database of systematic reviews 2015
B Prophylactic drug management for febrile seizures in children
Meta Analysis The Cochrane database of systematic reviews 2021
B Treatments for Hyperemesis Gravidarum and Nausea and Vomiting in Pregnancy: A Systematic Review
Systematic Review JAMA 2016
B The potential role of nutritional components in improving brain function among patients with Alzheimers disease: a meta-analysis of RCT studies
Meta Analysis Neurosciences (Riyadh, Saudi Arabia) 2020
B Pyridoxine (vitamin B6) supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2006
B Effect of ginger in the treatment of nausea and vomiting compared with vitamin B6 and placebo during pregnancy: a meta-analysis
Meta Analysis The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2022
View all evidence for Vitamin B6 →

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