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Anxioton

product on market Tablet or Pill Orthoplex Safety: 95/100
95/100

This product looks safe

  • Piper methysticum Root Extract Concentrate, Dry: 400mg is 1.6× the Tolerable Upper Intake Level (250mg)
  • 43% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This formula contains extracts from Kava, Ziziphus jujuba, Passionflower, and Magnolia officinalis, which are associated with anxiolytic and sedative effects. Research evidence for these ingredients is generally moderate, though overall evidence coverage for this specific profile is limited. The supplement maintains a high safety score of 95/100.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Piper methysticum Root Extract Concentrate, Dry: 400mg is 1.6× the Tolerable Upper Intake Level (250mg)

Label

Product Label

Label for Anxioton
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Tablet(s)
Serving Size
30
Servings
Botanical with Nutrients
Product Type
43%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Exceeds UL by 1.6× (UL: 250 mg) 15 studies (A:0, B:5)
Ziziphus jujuba var. spinosa Seed Extract Concentrate, Dry
300 mg
Market median: 250.0mg (60 products) 7 studies (A:0, B:1)
Magnolia officinalis Stem Bark Extract Concentrate, Dry
150 mg
Melissa officinalis Leaf Extract Concentrate, Dry
75 mg
50 mg
Within RDA (0.1× RDA) 316 studies (A:8, B:159)
Glycine
100 mg
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Adults Dose: Take 2 tablets once or twice daily.

Warnings & Precautions

For practitioner dispensing only

Keep out of reach of children

Warning: Large tablet. Swallow with a glass of water. Not for prolonged use. May harm the liver. Mineral and nutrient supplements should not replace a balanced diet. If symptoms persist, talk to your health professional. Do not use if tamper evidence seal is broken. Bottle sealed under cap for your protection.

Not recommended for use by pregnant or lactating women.

Formulation Notes

Traditional mild anxiety and sleeplessness

Indication: Contains Kava which is traditionally used in Pacific Island medicine as a clamative. Melissa and Passiflora are traditionally used in Western herbal medicine to relieve sleeplessness, symptoms of mild anxiety and support healthy sleeping patterns.

Proudly Australian owned

Additional Information

Aust L 457860

Store below 30 degrees C in a cool, dry place away from direct sunlight.

Metadata

Product Details

UPC / SKU9 319091 979784
DSLD Entry Date2024-12-21
Product TypeBotanical with Nutrients
FormTablet or Pill
BrandOrthoplex
DSLD ID327215
Data Updated2026-04-11
Research

Research Evidence

19
Research Sources
48
Avg Quality
8
Rct
5
Systematic Review
4
Meta Analysis
2
Clinical Trial
B Kava extract for treating anxiety
Meta Analysis The Cochrane database of systematic reviews 2003 PubMed
B Kava for Generalized Anxiety Disorder: A Review of Current Evidence
Meta Analysis Journal of alternative and complementary medicine (New York, N.Y.) 2018 PubMed DOI
B Kava extract for treating anxiety
Systematic Review The Cochrane database of systematic reviews 2001 PubMed
B Kava extract for treating anxiety
Systematic Review The Cochrane database of systematic reviews 2002 PubMed
B The effectiveness and safety of Kava Kava for treating anxiety symptoms: A systematic review and analysis of randomized clinical trials
Systematic Review Complementary therapies in clinical practice 2018 PubMed DOI
C Kava for generalised anxiety disorder: A 16-week double-blind, randomised, placebo-controlled study
Rct The Australian and New Zealand journal of psychiatry 2020 PubMed DOI
C Kava and St. John's Wort: current evidence for use in mood and anxiety disorders
Systematic Review Journal of alternative and complementary medicine (New York, N.Y.) 2009 PubMed DOI
C Neuroimaging Insights: Kava's (Piper methysticum) Effect on Dorsal Anterior Cingulate Cortex GABA in Generalized Anxiety Disorder.
Rct Nutrients PubMed DOI
C The risk-benefit profile of commonly used herbal therapies: Ginkgo, St. John's Wort, Ginseng, Echinacea, Saw Palmetto, and Kava
Meta Analysis Annals of internal medicine 2002 PubMed
C Efficacy of kava extract for treating anxiety: systematic review and meta-analysis
Meta Analysis Journal of clinical psychopharmacology 2000 PubMed
View all evidence for Kava →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.