Home/ Supplements/ Chromium/ 2-in-1 Cleanse & Flush

2-in-1 Cleanse & Flush

product on market Softgel Capsule Irwin Naturals Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 20% of ingredients have research evidence
B Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Chromium is the primary active ingredient, with moderate evidence suggesting it may support insulin sensitivity and glucose metabolism. The remaining profile consists of basic macronutrients with negligible physiological impact. Overall evidence coverage for this specific formulation is very limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for 2-in-1 Cleanse & Flush
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Liquid Soft-Gel(s)
Serving Size
30
Servings
Other Combinations
Product Type
20%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calories
20 Calorie(s)
Total Fat
1 Gram(s) (1% DV)
Total Carbohydrates
1 Gram(s) (1% DV)
Protein
1 Gram(s)
100 mcg (286% DV)
2.9× RDA — within safe limits 199 studies (A:1, B:55)
Extra Virgin Olive Oil
1100 mg
Market median: 250.0mg (562 products) 55 studies (A:0, B:19)
Cascara Sagrada Bark Extract
200 mg
Cinnamon Bark Extract
100 mg
Gymnema leaf extract
67.5 mg
Cardamom Fruit Extract
50 mg
Lemon Balm Aerial Extract
50 mg
Marshmallow Root Extract
50 mg
Market median: 450.0mg (254 products) 243 studies (A:0, B:100)
BioPerine Complex
3 mg

Other Ingredients

Gelatin Water, Purified Glycerin Beeswax Dextrin Soy Lecithin Turmeric Maltodextrin Titanium Dioxide Riboflavin Silicon Dioxide Sodium Copper Chlorophyllin
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Dictions: Take two (2) liquid soft-gels in the morning prior to breakfast and two (2) liquid soft-gels in the evening, prior to bedtime. Drink a full glass (8oz) of water with each serving. Do not exceed four (4) liquid soft-gels per day. If stools are loose, reduce intake to three (3) liquid soft-gels per day.

Warnings & Precautions

Usage warnings: Do not use if safety seal is broken. Do not use if you have an intestinal obstruction, bile duct obstruction, hemorrhoids or other intestinal disorders. Do not use if you are taking any other product concurrently that has laxative effects. Do not exceed recommended daily intake. Note: This product is not intended to be used without breaks. Cascara Sagrada belongs to a family of plants containing compounds with laxative effects. Can lead to dehydration and electrolyte loss. With long-term use without breaks, these ingredients may interfere with diagnostic imaging procedures of the colon. Taking a break of 30 or more days between use cycles will help maintain natural regularity. Not intended for long-term use.

Check with your doctor before using this product if you are using medication, including diuretics, heart medications, and corticosteroids, or have any medical conditions, including but not limited to diabetes or blood sugar disorders. Do not use if you may become pregnant, are pregnant or nursing.

Not intended for use by persons under 18. Keep out of reach of children.

Notice: This product contains Cascara Sagrada. Read and follow the directions carefully. Do not use if you have or develop diarrhea, loose stools, or abdominal pain because Cascara Sagrada may worsen these conditions and be harmful to your health.

Consult your physician if you have frequent diarrhea or if you are pregnant, nursing, taking medication, or have a medical condition.

Contains: Soy

Formulation Notes

2-in-1 Cleanse & Flush Weight Loss Support is a multi-pronged formula that is designed to cleanse your digestive tract and eliminate excess matter from the body. In just days, you can safely experience increased regularity, reduced bloating, and a flatter abdomen.

Cleanse & Flush: This powerful formula features Cascara Sagrada, a valuable botanical that is traditionally used to stimulate the bowels and gently flush excess waste from the digestive tract. We've combined this unique action with soothing Lemon Balm, as well as Marshmallow Root and Cardamom which have been used in traditional digestive formulas. Advanced cleansing support is supplied by potent milk thistle extract revered for its liver supporting benefits, and by concentrated Turmeric which exhibits powerful antioxidant activity. Weight management nutrition: Additional nutrition is delivered with 200 mcg of Chromium per day, along with Cinnamon Extract, and concentrated gymnema extract used traditionally to support energy balance and to eliminate excess water from the body. Patented BioPerine - Our special BioPerine Complex enhances the bioavailability, absorption and potency of many nutrients.

What makes us different: Liquid soft-gels - The nutrients in these easy-to-swallow liquid soft-gels are released fast. Other forms of delivery can contain binders and fillers that may cause stomach upset and offer no nutritional value. Advanced liquid soft-gels provide an optimum delivery system. Quality assurance - Irwin Naturals is committed to providing the highest quality products for your health. We employ compliance testing to ensure purity and potency.

2-in-1 Cleanse & Flush plus gymnema extract

Weight loss support Flush up to 2-to-3 pounds of backed-up matter Reduce excess water weight

No preservatives added.

Additional Information

Pass Quality Tested Guaranteed

Store in a cool, dry place.

Questions: Contact consume affairs 1-800-297-3273 - Weekdays 8:00 AM to 5:00 PM (PST) 100+ Highly specialized products: www.IrwinNaturals.com

Full disclosure ingredient panel

Metadata

Product Details

UPC / SKU7 10363 59711 5
DSLD Entry Date2025-01-23
Product TypeOther Combinations
FormSoftgel Capsule
DSLD ID323273
Data Updated2026-04-11
Research

Research Evidence

212
Research Sources
54
Avg Quality
102
Meta Analysis
79
Systematic Review
19
Rct
3
Narrative Review
3
Regulatory Source
2
Other
2
Clinical Trial
1
Openfda Safety
A 1-year outcomes with the Absorb bioresorbable scaffold in patients with coronary artery disease: a patient-level, pooled meta-analysis
Meta Analysis Lancet (London, England) 2016 PubMed DOI
B Interventions for preventing weight gain after smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
B Prenatal metal(loid) exposure and preterm birth: a systematic review of the epidemiologic evidence
Systematic Review Journal of exposure science & environmental epidemiology 2025 PubMed DOI
B Effects of cobalt-chromium everolimus eluting stents or bare metal stent on fatal and non-fatal cardiovascular events: patient level meta-analysis
Meta Analysis BMJ (Clinical research ed.) 2014 PubMed DOI
B Chromium picolinate supplementation for overweight or obese adults
Meta Analysis The Cochrane database of systematic reviews 2013 PubMed DOI
B Metalloestrogens exposure and risk of gestational diabetes mellitus: Evidence emerging from the systematic review and meta-analysis
Meta Analysis Environmental research 2024 PubMed DOI
B Trace elements in schizophrenia: a systematic review and meta-analysis of 39 studies (N = 5151 participants)
Meta Analysis Nutrition reviews 2020 PubMed DOI
B A meta-analysis of heavy metals pollution in farmland and urban soils in China over the past 20 years
Meta Analysis Journal of environmental sciences (China) 2021 PubMed DOI
B The spatiotemporal variation in heavy metals in China's farmland soil over the past 20 years: A meta-analysis
Meta Analysis The Science of the total environment 2022 PubMed DOI
B Human health risk assessment from potentially toxic elements in the soils of Sudan: A meta-analysis
Meta Analysis The Science of the total environment 2025 PubMed DOI
View all evidence for Chromium →
Compare

Similar Products

View all Chromium products →

This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.