🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 33% of ingredients have research evidence
A Label Compliance Grade

Product Label

📸

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Label Data

1 Tablet(s) Serving Size
90 Servings
Other Combinations Product Type
33% Evidence Coverage

Supplement Facts — Evidence Check

Diosmin
900 mg
📊 Market median: 100.0mg (284 products) 📚 10 studies (Tier A: 0, B: 4)
This product: 100mg
Hesperidin Methyl Chalcone
100 mg

Other Ingredients

Stearic Acid Dicalcium Phosphate Magnesium Stearate Microcrystalline Cellulose Croscarmellose Sodium Silica Shellac Povidone

Label Claims — Verification

All Other
Structure/Function
All Other (99% of products) Structure/Function (85% of products) Nutrient (9% of products)

Target Groups

Children 4 or More Years of Age Adult (18 - 50 Years)

Product Information

📋 Directions for Use

Directions: Adults and children 12 years of age and older: Take one tablet daily with food as a dietary supplement or as directed by physician.

⚠️ Warnings & Precautions

In case of an adverse event, please call 787-767-2072

Warning: If you are under a physician's care or taking medication, contact your physician before using this product. If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away.

Tamper evident: Do not use if cello-band around bottle neck is torn, broken or missing

🧪 Formulation Notes

Diosmin, 900 mg Grape Seed Extract, 100 mg Hesperidin Methyl Chalcone, 100 mg

Helps support leg vein health

Uses: Helps promote a healthy venous circulation. Helps support leg vein health

Additional Information

KramerNovis Pharmaceuticals within reach of patients

Other information: Store at controlled room temperature: 15 degrees - 30 degrees C (59 degrees - 86 degrees F).

Product Details

UPC / SKU 3 52083 90090 7
DSLD Entry Date 2024-11-22
Product Type Other Combinations
Form Tablet or Pill
Brand Kramer Novis
DSLD ID 322061
Data Updated 2026-04-11

Research Evidence

14 Research Sources
50 Avg Quality Score
9 Rct
2 Meta Analysis
2 Clinical Trial
1 Systematic Review
B Low Dose Monacolin K Combined with Coenzyme Q10, Grape Seed, and Olive Leaf Extracts Lowers LDL Cholesterol in Patients with Mild Dyslipidemia: A Multicenter, Randomized Controlled Trial
Rct Nutrients 2023
B Efficacy of Bilberry and Grape Seed Extract Supplement Interventions to Improve Glucose and Cholesterol Metabolism and Blood Pressure in Different Populations-A Systematic Review of the Literature
Systematic Review Nutrients 2021
B The effect of grape seed extract on cardiovascular risk markers: a meta-analysis of randomized controlled trials
Meta Analysis Journal of the American Dietetic Association 2011
B The impact of grape seed extract treatment on blood pressure changes: A meta-analysis of 16 randomized controlled trials
Meta Analysis Medicine 2016
B Grape Seed Extract Positively Modulates Blood Pressure and Perceived Stress: A Randomized, Double-Blind, Placebo-Controlled Study in Healthy Volunteers
Rct Nutrients 2021
C Effects of grape seed extract beverage on blood pressure and metabolic indices in individuals with pre-hypertension: a randomised, double-blinded, two-arm, parallel, placebo-controlled trial
Rct The British journal of nutrition 2016
C Effect of grape seed extract on blood pressure in subjects with the metabolic syndrome
Rct Metabolism: clinical and experimental 2009
C Grape seed extract supplementation along with a restricted-calorie diet improves cardiovascular risk factors in obese or overweight adult individuals: A randomized, placebo-controlled trial
Rct Phytotherapy research : PTR 2021
C The effect of polyphenol-rich chardonnay seed supplements on peripheral endothelial function.
Rct European journal of nutrition
C The effects of grape seed extract supplementation on cardiovascular risk factors, liver enzymes and hepatic steatosis in patients with non-alcoholic fatty liver disease: a randomised, double-blind, placebo-controlled study.
Rct BMC complementary medicine and therapies
View all evidence for Grape Seed →

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