5-HTP 50 mg

product on market Capsule H&B Holland & Barrett 🟢 Safety: 100/100
Brand: H&B Holland & Barrett
🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 75% of ingredients have research evidence
A Label Compliance Grade

Product Label

Label for 5-HTP 50 mg
📄 Open Full PDF View on NIH DSLD →
📸

Have a supplement label? Find it here.

Upload a photo of any supplement label to search our database of 92,312 products.

Label Data

1 Capsule(s) Serving Size
120 Servings
Botanical with Nutrients Product Type
75% Evidence Coverage

Supplement Facts — Evidence Check

5 mg NE (31% DV)
✅ Within RDA (0.4× RDA of 14 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 5mg UL 35mg
5 mg (357% DV)
📊 3.8× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 5mg UL 100mg
25 mg (7% DV)
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 25mg
Griffonia seed extract
250 mg

Other Ingredients

Griffonia seed extract Hydroxypropyl Methylcellulose Maltodextrin Magnesium Oxide Vitamin B6 Niacin Magnesium Stearate

Label Claims — Verification

❓ Nutrient
❓ All Other
All Other (99% of products) Structure/Function (78% of products) Nutrient (52% of products)

Target Groups

Vegan Vegetarian Adult (18 - 50 Years) Dairy Free

Product Information

📋 Directions for Use

Directions: Take 1-2 capsules per day, as needed or before bedtime.

1 a day

⚠️ Warnings & Precautions

Do not exceed stated dose. Food supplements must not be used as a substitute for a varied and balanced diet and a healthy lifestyle. Discontinue use and consult a doctor if adverse reactions occur. Do not use if seal under cap is broken or missing.

If you are pregnant, breastfeeding, taking any medications or under medical supervision, please consult a doctor or healthcare professional before use.

Keep out of sight and reach of children. This product is not intended for use by persons under the age of 18.

🧪 Formulation Notes

All our products are subject to our stringent quality assurance.

This product doesn't contain artificial flavours, colours or sweeteners.

Griffonia Simplicifolia Extract 250 mg Providing 20% 5-HTP 50 mg

Vegan

Additional Information

NRV = Nutrient Reference Value

I'm recycled plastic

Bottle made from at least 80% recycled plastic. Please recycle bottle with cap on.

Store in a cool, dry place.

Product Details

DSLD Entry Date 2025-01-23
Product Type Botanical with Nutrients
Form Capsule
Brand H&B Holland & Barrett
DSLD ID 321884
Data Updated 2026-04-11

Research Evidence

21 Research Sources
53 Avg Quality Score
11 Systematic Review
6 Rct
4 Meta Analysis
B Combination pharmacotherapy for the treatment of fibromyalgia in adults
Systematic Review The Cochrane database of systematic reviews 2018
PubMed DOI
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2001
PubMed Cochrane
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2002
PubMed Cochrane
B The impact of 5-hydroxytryptophan supplementation on sleep quality and gut microbiota composition in older adults: A randomized controlled trial
Rct Clinical nutrition (Edinburgh, Scotland) 2024
PubMed DOI
B The Impact of 5-Hydroxytryptophan Supplementation on Cognitive Function and Mood in Singapore Older Adults: A Randomized Controlled Trial
Rct Nutrients 2025
PubMed DOI
B The Efficacy of Different Triptans for the Treatment of Acute Headache in Pediatric Migraine: A Systematic Review
Systematic Review Indian pediatrics 2023
PubMed
B The effect of therapeutic massage combined with conventional therapy in children with functional dyspepsia: a systematic review and meta-analysis
Systematic Review Frontiers in pharmacology 2025
PubMed DOI
C Sleep disorders in children
Systematic Review BMJ clinical evidence 2010
PubMed
C Effects of 5-hydroxytryptophan on distinct types of depression: a systematic review and meta-analysis
Meta Analysis Nutrition reviews 2020
PubMed DOI
C Investigating genetic links between biological aging and adverse pregnancy outcomes
Meta Analysis Biogerontology 2025
PubMed DOI
View all evidence for 5 Htp →

Compare Similar Products

5-HTP
5-HTP XYMOGEN 100
5-HTP 100 mg
5-HTP 100 mg VitaCeutical Labs 100
5-HTP 5-Hydroxy-L-Trytophan 50
5-HTP 5-Hydroxy-L-Trytophan 50 LifeLink 100
5-HTP 5-Hydroxy-L-Trytophan 50
5-HTP 5-Hydroxy-L-Trytophan 50 LifeLink 100
5-HTP 5-Hydroxy-L-Trytophan 100
5-HTP 5-Hydroxy-L-Trytophan 100 LifeLink 100
View all 5 Htp products →
5 Htp research & evidence Best 5 Htp rankings All 5 Htp products More from H&B Holland & Barrett View on NIH DSLD →