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I3C + DIM

product on market Capsule Wellness Resources Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 50% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

Indole-3-carbinol and diindolylmethane are researched for their roles in modulating estrogen metabolism. Current evidence for these compounds is limited, though they are generally associated with supporting hormonal balance. There are no significant safety concerns noted for this profile.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for I3C + DIM
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
60
Servings
Non-Nutrient/Non-Botanical
Product Type
50%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Indole-3-Carbinol
300 mg
Market median: 200.0mg (3 products) 11 studies (A:1, B:3)

Other Ingredients

Cellulose Rice hull
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: Take 1 capsule, 1 to 2 times per day.

Formulation Notes

I3C + DIM contains cruciferous vegetable extracts that support healthy estrogen metabolism and balance, in both women and men.

Estrogen metabolism support

Metadata

Product Details

DSLD Entry Date2025-02-23
Product TypeNon-Nutrient/Non-Botanical
FormCapsule
BrandWellness Resources
DSLD ID320626
Data Updated2026-04-11
Research

Research Evidence

5
Research Sources
44
Avg Quality
5
Rct
C A randomized, placebo-controlled trial of diindolylmethane for breast cancer biomarker modulation in patients taking tamoxifen
Rct Breast cancer research and treatment 2017 PubMed DOI
C Phase Ib placebo-controlled, tissue biomarker trial of diindolylmethane (BR-DIMNG) in patients with prostate cancer who are undergoing prostatectomy
Rct European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 2016 PubMed DOI
C Effectiveness of 3,3'-Diindolylmethane Supplements on Favoring the Benign Estrogen Metabolism Pathway and Decreasing Body Fat in Premenopausal Women
Rct Nutrition and cancer 2023 PubMed DOI
C The effects of light exposure on the cortisol stress response in human males.
Rct Stress (Amsterdam, Netherlands) PubMed DOI
D Pilot study: effect of 3,3'-diindolylmethane supplements on urinary hormone metabolites in postmenopausal women with a history of early-stage breast cancer
Rct Nutrition and cancer 2004 PubMed
View all evidence for Dim →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.