Vitamins D3 2500 IU (62.5 mcg) & K2 120 mcg

product on market Tablet or Pill NaturesPlus 🟢 Safety: 100/100
Brand: NaturesPlus
🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

Vitamin D3 and K2 are supported by strong evidence for promoting bone health and calcium regulation. Research indicates that these nutrients work synergistically to ensure calcium is properly absorbed and deposited in the skeletal system. The combination is generally recognized as safe for most adults.

AI-generated summary based on research evidence. Not medical advice.

Product Label

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Label Data

1 Tablet(s) Serving Size
90 Servings
Vitamin Product Type
100% Evidence Coverage

Supplement Facts — Evidence Check

62.5 mcg (313% DV)
📊 4.2× RDA — above typical dose (UL: 0.1 mg) 📚 608 studies (Tier A: 16, B: 251)
RDA 0.015mg This product: 0.0625mg UL 0.1mg
120 mcg (100% DV)
✅ Within RDA (1.0× RDA of 0.12 mg) 📚 275 studies (Tier A: 9, B: 175)
RDA 0.12mg This product: 0.12mg

Other Ingredients

Microcrystalline Cellulose Silica Rice Bran Tapioca Maltodextrin Cellulose

Label Claims — Verification

❓ Nutrient
❓ All Other
❓ Structure/Function
All Other (99% of products) Structure/Function (85% of products) Nutrient (70% of products) Approved Health (4% of products)

Target Groups

Vegetarian Adult (18 - 50 Years) No Allergies Gluten Free Dairy Free

Product Information

📋 Directions for Use

Directions: One tablet daily.

⚠️ Warnings & Precautions

Keep out of reach of children.

🧪 Formulation Notes

Extensive studies of Vitamins D3 and K2 in calcium metabolism indicate these two vitamins have a synergistic relationship in supporting bone strength and cardiovascular health. Vitamin D3 is also recognized for its role in immune health, while vitamin K2 is known to help direct calcium to bones rather than arteries and joint spaces.

No Magnesium Stearate Gluten free

Vegetarian

Bone Support

Free from synthetic: colors, preservatives. Free from milk, eggs, fish, crustacean shellfish, tree nuts, peanuts, wheat, soy and sesame.

Additional Information

Keep tightly closed in a cool, dry place.

Product Details

UPC / SKU 0 97467 10436 5
DSLD Entry Date 2024-11-22
Product Type Vitamin
Form Tablet or Pill
Brand NaturesPlus
DSLD ID 320569
Data Updated 2026-04-11

Research Evidence

872 Research Sources
53 Avg Quality Score
309 Meta Analysis
309 Clinical Trial
111 Rct
71 Systematic Review
55 Guideline
4 Cochrane Review
4 Regulatory Source
2 Other
2 Narrative Review
2 Observational
1 Openfda Safety
A Vitamin D and vitamin D analogues for preventing fractures associated with involutional and post-menopausal osteoporosis
Meta Analysis The Cochrane database of systematic reviews 2009
PubMed DOI Cochrane
A Vitamin D supplementation for prevention of mortality in adults
Meta Analysis The Cochrane database of systematic reviews 2014
PubMed DOI Cochrane
A Vitamin D and vitamin D analogues for preventing fractures in post-menopausal women and older men
Meta Analysis The Cochrane database of systematic reviews 2014
PubMed DOI Cochrane
A Vitamin D supplementation for prevention of cancer in adults
Meta Analysis The Cochrane database of systematic reviews 2014
PubMed DOI Cochrane
A Interventions for preventing falls in older people in care facilities and hospitals
Meta Analysis The Cochrane database of systematic reviews 2018
PubMed DOI
A Drugs for preventing lung cancer in healthy people
Meta Analysis The Cochrane database of systematic reviews 2020
PubMed DOI
A Vitamin D supplementation for prevention of mortality in adults
Meta Analysis The Cochrane database of systematic reviews 2011
PubMed DOI Cochrane
A High prevalence of vitamin D deficiency in Asia: A systematic review and meta-analysis
Meta Analysis Critical reviews in food science and nutrition 2023
PubMed DOI
A The effect of vitamin D supplementation on depressive symptoms in adults: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Critical reviews in food science and nutrition 2023
PubMed DOI
A Interventions for preventing falls in older people living in the community
Meta Analysis The Cochrane database of systematic reviews 2009
PubMed DOI
View all evidence for Vitamin D →

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