Home/ Supplements/ Citrulline/ Nitric Oxide MD +BioPerine

Nitric Oxide MD +BioPerine

product on market Capsule Approved Science Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 17% of ingredients have research evidence
B Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

L-arginine and L-citrulline are supported by moderate evidence for increasing nitric oxide levels to support blood flow. Pine bark extract and quercetin provide additional antioxidant support, while longjack extract has limited evidence for enhancing vitality. Together, these ingredients target cardiovascular and metabolic function through vasodilatory pathways.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Nitric Oxide MD +BioPerine
Open Full PDF View on NIH DSLD →
Details

Label Data

3 Capsule(s)
Serving Size
30
Servings
Other Combinations
Product Type
17%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Market median: 500.0mg (143 products)
480 mg
Market median: 2000.0mg (275 products)
Pine Bark Extract
30 mg
30 mg
Market median: 500.0mg (283 products) 174 studies (A:0, B:62)
Longjack extract
30 mg
BioPerine
5 mg

Other Ingredients

Cellulose
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: On workout days: Take 3 capsules before breakfast and 3 capsules, 30 minutes before a workout with an 8 oz. glass of water. On rest days: Take 3 capsules before breakfast and 3 capsules before dinner with an 8 oz. glass of water.

Warnings & Precautions

Caution: Do not exceed recommended dose. Do not use if safety seal is damaged or missing.

Pregnant women or nursing mothers, children under 18, and individuals with a known medical condition, should consult with a physician before taking this or any other dietary supplement.

Pregnant women or nursing mothers, children under 18, and individuals with a known medical condition, should consult with a physician before taking this or any other dietary supplement. Keep out of reach of children.

Formulation Notes

Manufactured in the USA according to current Good Manufacturing Practice (cGMP) and conforms to the tested ingredient grade, strength and purity of industry Quality Standards.

Vegan friendly

Made with GMO free ingredients

Advanced health support Premium grade High potency Safe Fast Natural formula Optimal strength GMP Certified

Contains Nitri-Sci 1680mg L-arginine Blend

100% vegan friendly

Additional Information

Vegan friendly Made in USA No animal testing GMP Good Manufacturing Practice Quality Product

Metadata

Product Details

UPC / SKUX00287O8LL
DSLD Entry Date2024-11-22
Product TypeOther Combinations
FormCapsule
BrandApproved Science
DSLD ID319800
Data Updated2026-04-11
Research

Research Evidence

12
Research Sources
45
Avg Quality
6
Rct
5
Clinical Trial
1
Meta Analysis
C Effect of food sources of nitrate, polyphenols, L-arginine and L-citrulline on endurance exercise performance: a systematic review and meta-analysis of randomised controlled trials
Meta Analysis Journal of the International Society of Sports Nutrition 2021 PubMed DOI
C Effects of L-Citrulline Supplementation on Endothelial Function and Blood Pressure in Hypertensive Postmenopausal Women.
Rct Nutrients PubMed DOI
C Effects of Acute Citrulline Malate Supplementation on CrossFit® Exercise Performance: A Randomized, Double-Blind, Placebo-Controlled, Cross-Over Study.
Rct Nutrients PubMed DOI
C Impact of L-Citrulline Supplementation and HIIT on Lipid Profile, Arterial Stiffness, and Fat Mass in Obese Adolescents with Metabolic-Dysfunction-Associated Fatty Liver Disease: A Randomized Clinical Trial.
Rct Nutrients PubMed DOI
C Effect of L-Citrulline Supplementation on NAFLD in Adolescents With Obesity
Clinical Trial ClinicalTrials.gov 2021
C Effects of L-Citrulline or Citrulline-malate on Neuromuscular Performance in Resistance-trained Adults
Clinical Trial ClinicalTrials.gov 2022
C Acute effects of Nitrosigine® and citrulline malate on vasodilation in young adults.
Rct Journal of the International Society of Sports Nutrition PubMed DOI
C Effects of Combined Versus Single Supplementation of Creatine, Beta-Alanine, and L-Citrulline During Short Sprint Interval Training on Basketball Players' Performance: A Double-Blind Randomized Placebo-Controlled Trial.
Rct International journal of sports physiology and performance PubMed DOI
C Acute effects of combined supplementation of L-arginine and citrulline malate on aerobic, anaerobic, and CrossFit exercise performance.
Rct Scientific reports PubMed DOI
C L-Citrulline in Peripheral Artery Disease
Clinical Trial ClinicalTrials.gov 2016
View all evidence for Citrulline →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.