CellularActive Methylfolate 1000 mcg Raspberry Flavor by Bluebonnet EarthSweet Chewables

80/100

This product is generally safe

Folate: 1667mg is 1667.0× the Tolerable Upper Intake Level (1.0mg)
50% of ingredients have research evidence

C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

Methylfolate is a bioactive form of folate that supports cellular methylation and neurological function, with strong evidence for its role in folate metabolism. Carbohydrates in this formulation serve as a delivery vehicle for the active ingredient. Research indicates these components are generally well-tolerated and safe for most users.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Folate: 1667mg is 1667.0× the Tolerable Upper Intake Level (1.0mg)

Label

Product Label

Open Full PDF View on NIH DSLD →

Details

Label Data

1 Tablet(s)

Serving Size

Servings

Vitamin

Product Type

50%

Evidence Coverage

Ingredients

Supplement Facts — Evidence Check

Total Carbohydrates

1 Gram(s) (1% DV)

Folate

1667 mcg DFE (417% DV)

Exceeds UL by 1667.0× (UL: 1.0 mg) 226 studies (A:10, B:105)

Other Ingredients

Sugar Raspberry Flavor, Natural Strawberry Flavor, Natural Stearic Acid Magnesium Stearate Grape, Powder Grape Seed Extract, Powder Wild Blueberry, Powder Wild Blueberry Extract, Powder Raspberry, Powder Raspberry Seed Concentrate, Powder Cranberry, Powder Prune, Powder Tart Cherry, Powder Wild Bilberry, Powder Wild Bilberry Extract, Powder Strawberry, Powder Cellulose

Claims

Label Claims — Verification

Unverified Nutrient

Unverified All Other

Unverified Structure/Function

Info

Product Information

Directions for Use

Directions: As a dietary supplement, take one chewable tablet daily or as directed by a healthcare practitioner.

Warnings & Precautions

Caution: For adults only Keep out of reach of children.

Consult physician if pregnant/nursing, taking medication, or have a medical condition.

Formulation Notes

Free of milk, egg, fish, crustacean shellfish, tree nuts, peanuts, wheat, soybeans and sesame. Also free of gluten, barley, rice and sodium.

Bluebonnet's KOF-K Certification #K-0000700

Quatrefolic

Non-GMO Gluten free

Vegan

K Parve (Kosher)

Energy, mood & prenatal health

Raspberry Flavor with other natural flavors

Bluebonnet's EarthSweet Chewables CellularActive Methylfolate 1000 mcg tablets are formulated with Quatrefolic, a patented and clinically studied coenzyme form of folate for prenatal health, energy and vitality, as well as mood support in a delicious raspberry flavor. Sweetened with EarthSweet, a proprietary sweetening mix of fruit powders and sugar cane crystals.

Additional Information

Store tightly closed in a cool, dry place.

K Parve (Kosher)

Metadata

Product Details

UPC / SKU7 43715 00455 9

DSLD Entry Date2024-10-24

Product TypeVitamin

FormTablet or Pill

BrandBluebonnet EarthSweet Chewables

DSLD ID314937

Data Updated2026-04-11

Research

Research Evidence

363

Research Sources

Avg Quality

187

Meta Analysis

Systematic Review

Rct

Guideline

Clinical Trial

Cochrane Review

Regulatory Source

Other

Openfda Safety

A Homocysteine-lowering interventions for preventing cardiovascular events

Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI

A Community-based intervention packages for reducing maternal and neonatal morbidity and mortality and improving neonatal outcomes

Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI

A Folate Intake and Risk of Pancreatic Cancer: A Systematic Review and Updated Meta-Analysis of Epidemiological Studies

Meta Analysis Digestive diseases and sciences 2021 PubMed DOI

A The Association Between the Risk of Hypertensive Disorders of Pregnancy and Folic Acid: A Systematic Review and Meta-Analysis

Meta Analysis Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 2021 PubMed DOI

A A Comparative Study Evaluating the Effectiveness of Folate-Based B Vitamin Intervention on Cognitive Function of Older Adults under Mandatory Folic Acid Fortification Policy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Meta Analysis Nutrients 2024 PubMed DOI

A Associations between serum Homocysteine, vitamin B9, and vitamin B12 levels and the formation of intracranial Aneurysms: A systematic review and meta-analysis

Meta Analysis Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2025 PubMed DOI

A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies

Meta Analysis Critical reviews in food science and nutrition 2019 PubMed DOI

A Beneficial effects of folic acid supplementation on lipid markers in adults: A GRADE-assessed systematic review and dose-response meta-analysis of data from 21,787 participants in 34 randomized controlled trials

Meta Analysis Critical reviews in food science and nutrition 2022 PubMed DOI

A Folic acid supplementation and blood pressure: a GRADE-assessed systematic review and dose-response meta-analysis of 41,633 participants

Meta Analysis Critical reviews in food science and nutrition 2023 PubMed DOI

A Digital tracking, provider decision support systems, and targeted client communication via mobile devices to improve primary health care

Meta Analysis The Cochrane database of systematic reviews 2025 PubMed DOI

View all evidence for Folate →

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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.