Home/ Supplements/ Betaine/ TMG Betaine - 1,000 mg

TMG Betaine - 1,000 mg

product on market Tablet or Pill NOW Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • Limited research evidence available for ingredients
B Label Compliance Grade
Label

Product Label

Label for TMG Betaine - 1,000 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Tablet(s)
Serving Size
33
Servings
Non-Nutrient/Non-Botanical
Product Type
0%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

3 Gram(s)
Market median: 496.0mg (192 products) 20 studies — no high-quality reviews

Other Ingredients

Microcrystalline Cellulose Hydroxypropyl Cellulose Vegetarian Coating Stearic Acid Croscarmellose Sodium Magnesium Stearate
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested Usage: Take 1-3 tablets twice daily, preferably with food.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Warnings & Precautions

Caution: For adults only. Keep out of reach of children.

Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish, tree nut or sesame ingredients.

Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish, tree nut or sesame ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

Formulation Notes

Betaine Anhydrous, or TMG (Trimethylglycine) is known to facilitate methylation processes. Methylation is a normal biological process that is critical for DNA repair, liver detoxification mechanisms, lipid metabolism, and the production of SAMe. It is also an important step in the conversion of homocysteine, a damaging amino acid, into a friendlier amino acid, methionine. Supplementation with TMG has been shown in clinical and non-clinical studies to support healthy homocysteine levels already within normal range.

Consult physician if pregnant/nursing, taking medication, or have a medical condition.

Liver Support Supports Healthy Homocysteine Levels Promotes Normal Methylation Processes

Non-GMO

Vegetarian/Vegan

Triangle K (Kosher)

Made and quality tested in the USA with globally sourced ingredients.

Natural color variation may occur in this product.

Additional Information

Keep the bottle tightly closed at all times in between usage. Keep the freshness packet in bottle. This product is very sensitive to moisture/humidity which may affect product stability. Store in a cool, dry place after opening.

Triangle K (Kosher)

Vitamins Family owned since 1968.

GMP Quality Assured

Metadata

Product Details

UPC / SKU7 33739 00494 9
DSLD Entry Date2024-11-22
Product TypeNon-Nutrient/Non-Botanical
FormTablet or Pill
BrandNOW
DSLD ID314138
Data Updated2026-04-11
Research

Research Evidence

23
Research Sources
47
Avg Quality
18
Rct
3
Systematic Review
1
Meta Analysis
1
Clinical Trial
B Effect of Folic Acid, Betaine, Vitamin B₆, and Vitamin B12 on Homocysteine and Dimethylglycine Levels in Middle-Aged Men Drinking White Wine
Rct Nutrients 2016 PubMed DOI
C Betaine for nonalcoholic fatty liver disease: results of a randomized placebo-controlled trial
Rct Hepatology (Baltimore, Md.) 2009 PubMed DOI
C Guidelines for the diagnosis and management of cystathionine beta-synthase deficiency
Systematic Review Journal of inherited metabolic disease 2017 PubMed DOI
C Newborn screening for homocystinurias and methylation disorders: systematic review and proposed guidelines
Systematic Review Journal of inherited metabolic disease 2015 PubMed DOI
C Effects of low-dose B vitamins plus betaine supplementation on lowering homocysteine concentrations among Chinese adults with hyperhomocysteinemia: a randomized, double-blind, controlled preliminary clinical trial
Rct European journal of nutrition 2023 PubMed DOI
C Association of Betaine-Homocysteine S-Methyl Transferase (rs3797546 and rs3733890) polymorphisms with non-syndromic cleft lip/palate: A meta-analysis
Meta Analysis International orthodontics 2019 PubMed DOI
C Two methods for assessment of choline status in a randomized crossover study with varying dietary choline intake in people: isotope dilution MS of plasma and in vivo single-voxel magnetic resonance spectroscopy of liver.
Rct The American journal of clinical nutrition PubMed DOI
C Effect of inulin supplementation on fecal and blood metabolome in alcohol use disorder patients: A randomised, controlled dietary intervention.
Rct Clinical nutrition ESPEN PubMed DOI
C Choline and betaine concentrations in plasma discriminate levels of dietary choline intake in healthy adults: analysis of a double-blind randomized crossover controlled feeding study.
Rct The American journal of clinical nutrition PubMed DOI
C Fibrates may cause an abnormal urinary betaine loss which is associated with elevations in plasma homocysteine
Rct Cardiovascular drugs and therapy 2009 PubMed DOI
View all evidence for Betaine →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.