🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 67% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

1 Tablet(s) Serving Size
120 Servings
Non-Nutrient/Non-Botanical Product Type
67% Evidence Coverage

Supplement Facts — Evidence Check

📊 Market median: 1000.0mg (1115 products) 📚 22 studies (Tier A: 0, B: 9)
This product: 375mg
📊 Market median: 600.0mg (79 products) 📚 24 studies (Tier A: 0, B: 6)
This product: 300mg
OptiMSM
375 mg

Other Ingredients

Cellulose Modified Cellulose Gum Stearic Acid Magnesium Stearate Silica Glycerin

Label Claims — Verification

All Other
Structure/Function
All Other (100% of products) Structure/Function (89% of products) Nutrient (16% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free Dairy Free

Product Information

📋 Directions for Use

Suggested use: Take one tablet daily with food up to three times daily.

⚠️ Warnings & Precautions

To report a serious adverse event, call 1-888-710-0006

This product contains glucosamine sulfate from shell fish.

Keep out of reach of children.

🧪 Formulation Notes

Glucosamine, chondroitin, and MSM are three popular ingredients that are combined to provide comprehensive joint support. Our glucosamine complex provides a special blend of three sources of glucosamine, including glucosamine sulfate, n-acetyl d-glucosamine, and glucosamine hydrochloride. Glucosamine is a building block of joint tissue, and helps the body manufacture substances necessary for healthy joints. Chrondroitin is a natural extract from beef cartilage and helps fight the breakdown of tissue and cartilage in the body. MSM provides naturally occurring organic sulfur, which is a necessary component for making collagen, a primary constituent of joints, cartilage and other connective tissues. Used in combination, our Glucosamine Chondroitin MSM formula provides a convenient supplement to support healthy joints.

We guarantee our supplements for potency and purity

Supports healthy joints

Double Verified Gluten Free

Contains no artificial colors, flavors or preservatives, no wheat, gluten, milk, eggs, peanuts, tree nuts, soy or fish.

Additional Information

Double Verified Gluten Free

Product Details

DSLD Entry Date 2024-05-23
Product Type Non-Nutrient/Non-Botanical
Form Tablet or Pill
DSLD ID 310227
Data Updated 2026-04-11

Research Evidence

39 Research Sources
50 Avg Quality Score
20 Rct
9 Meta Analysis
4 Clinical Trial
3 Systematic Review
1 Regulatory Source
1 Openfda Safety
B Interventions for the management of temporomandibular joint osteoarthritis
Systematic Review The Cochrane database of systematic reviews 2012
B Glucosamine therapy for treating osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2005
B Chondroitin for osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2015
B Efficacy and safety of the combination of glucosamine and chondroitin for knee osteoarthritis: a systematic review and meta-analysis
Meta Analysis Archives of orthopaedic and trauma surgery 2023
B Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis
Rct The New England journal of medicine 2006
B Oral Glucosamine in the Treatment of Temporomandibular Joint Osteoarthritis: A Systematic Review
Systematic Review International journal of molecular sciences 2023
B Scientific Opinion on glucosamine and joint health
Regulatory Source EFSA Journal 2009
B Clinical Efficacy and Safety of Chondroitin Combined with Glucosamine in the Treatment of Knee Osteoarthritis: A Systematic Review and Meta-Analysis
Meta Analysis Computational and mathematical methods in medicine 2022
B Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib
Rct Annals of the rheumatic diseases 2016
B Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trials
Meta Analysis Journal of orthopaedic surgery and research 2018
View all evidence for Glucosamine →

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