Vegan B12 by 1MD Nutrition — Ingredients, Evidence & Safety

🟢 100/100

This product looks safe

No ingredients exceed tolerable upper intake levels
100% of ingredients have research evidence

A Label Compliance Grade

Product Label

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Label Data

1 Softgel(s) Serving Size

30 Servings

Vitamin Product Type

100% Evidence Coverage

Supplement Facts — Evidence Check

Vitamin B12

5000 mcg (208333% DV)

📊 2083.3× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)

RDA 0.0024mg This product: 5.0mg

Other Ingredients

Olive Oil Water Tapioca Starch Glycerin Candelilla Wax Sunflower Lecithin Beet natural Carotenoids

Label Claims — Verification

❓ All Other

❓ Structure/Function

All Other (99% of products) Structure/Function (89% of products) Nutrient (56% of products)

Target Groups

Vegan Vegetarian Adult (18 - 50 Years) Dairy Free

Product Information

📋 Directions for Use

Suggested Use: As a dietary supplement, adults take one (1) softgel, once (1x) daily, or as recommended by a healthcare practitioner.

⚠️ Warnings & Precautions

Warning: Consult a healthcare practitioner if you are pregnant or nursing, have a serious medical condition, or use any medications.

Keep out of reach of children.

Do not use if safety seal is damaged or missing.

🧪 Formulation Notes

Manufactured in the USA from globally-sourced ingredients. GMP Good Manufacturing Practice

Comprehensive cardiovascular support Promotes heart health Aids cognitive function Supports immune health

Color may vary.

Non-GMO Shellfish-free Wheat-free Peanut-free Dairy-free

Additional Information

Questions? Call: (888) 393-4030 Email: support@1md.org Visit: www.1md.org

Store in a cool, dry place.

1MD Nutrition Vegan...asy-swallow softgels New

Product Details

UPC / SKU X00303HB1V

DSLD Entry Date 2024-03-22

Product Type Vitamin

Form Softgel Capsule

Brand 1MD Nutrition

DSLD ID 309826

Data Updated 2026-04-11

Research Evidence

237 Research Sources

53 Avg Quality Score

83 Meta Analysis

74 Systematic Review

45 Rct

29 Clinical Trial

2 Guideline

2 Regulatory Source

1 Openfda Safety

A Associations between serum Homocysteine, vitamin B9, and vitamin B12 levels and the formation of intracranial Aneurysms: A systematic review and meta-analysis

Meta Analysis Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2025

PubMed DOI

A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies

Meta Analysis Critical reviews in food science and nutrition 2019

PubMed DOI

A Oral vitamin B12 versus intramuscular vitamin B12 for vitamin B12 deficiency

Systematic Review The Cochrane database of systematic reviews 2018

PubMed DOI Cochrane

A Effects of Vitamin B12 Supplementation on Cognitive Function, Depressive Symptoms, and Fatigue: A Systematic Review, Meta-Analysis, and Meta-Regression

Meta Analysis Nutrients 2021

PubMed DOI

A Efficacy of different routes of vitamin B12 supplementation for the treatment of patients with vitamin B12 deficiency: A systematic review and network meta-analysis

Systematic Review Irish journal of medical science 2024

PubMed DOI

B Helicobacter pylori infection and micronutrient deficiency in pregnant women: a systematic review and meta-analysis

Meta Analysis BMJ open gastroenterology 2020

PubMed DOI

B Vitamin B12 supplementation during pregnancy for maternal and child health outcomes

Systematic Review The Cochrane database of systematic reviews 2024

PubMed DOI Cochrane

B A comprehensive review and meta-regression analysis of randomized controlled trials examining the impact of vitamin B12 supplementation on homocysteine levels

Meta Analysis Nutrition reviews 2024

PubMed DOI

B Relationship between vitamin B12 levels and motor development: A systematic review

Systematic Review Clinical nutrition ESPEN 2024

PubMed DOI

B Vitamin B12, folate, and homocysteine in metabolic syndrome: a systematic review and meta-analysis

Meta Analysis Frontiers in endocrinology 2023

PubMed DOI

View all evidence for Vitamin B12 →