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Niacin 500 mg

product on market Tablet or Pill Best Naturals Safety: 60/100
60/100

Review before taking

  • Niacin: 500mg is 14.3× the Tolerable Upper Intake Level (35mg)
  • 100% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Niacin is used to support cholesterol management and energy metabolism, though evidence for general supplementation is limited. Due to a safety score of 60, users should be aware of potential side effects such as skin flushing. Consult a professional regarding dosage and safety.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 500mg is 14.3× the Tolerable Upper Intake Level (35mg)

✨ AI-generated · Qwen 3.6 · grounded in 2 sources · methodology

This product received a low safety score because the amount of Niacin is over 14 times higher than the recommended daily upper limit.

Label

Product Label

Label for Niacin 500 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Tablet(s)
Serving Size
250
Servings
Vitamin
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

500 mg (3125% DV)
Exceeds UL by 14.3× (UL: 35 mg) 196 studies (A:5, B:63)

Other Ingredients

Microcrystalline Cellulose Dicalcium Phosphate Stearic Acid Croscarmellose Sodium Magnesium Stearate Silicon Dioxide Pharmaceutical Glaze
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested use: Take 1 tablet daily with a meal. This high potency tablet should be taken under doctor's supervision.

Warnings & Precautions

Caution: For adults only. Keep out of reach of children. Keep out of the reach of children.

Physician supervision is recommended while taking this product. Transient GI symptoms may occur at inception of treatment, consult physician if symptoms persist. Do not use if safety seal is broken or missing.

Not recommended for pregnant/nursing women. Notify physician if taking medication (especially anticoagulant medications, including NSAIDs) or have a medical condition (especially cardiovascular disease, liver problems, inflammatory bowel disease, diabetes, gout, or migraine headaches.

Formulation Notes

Premium formula

3rd Party lab tested

No artificial color, flavor or sweetener, no preservatives, no sugar, no starch, no corn, no soy, no egg, no milk, no lactose, no gluten, no wheat, no yeast.

Additional Information

Keep in cool, dry place.

Made in USA

GMP Good Manufacturing Practice Product

Metadata

Product Details

UPC / SKU8 17716 01558 3
DSLD Entry Date2024-01-24
Product TypeVitamin
FormTablet or Pill
BrandBest Naturals
DSLD ID306008
Data Updated2026-04-11
Research

Research Evidence

241
Research Sources
55
Avg Quality
113
Meta Analysis
75
Systematic Review
32
Rct
11
Clinical Trial
3
Other
3
Regulatory Source
1
Cochrane Review
1
Narrative Review
1
Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013 PubMed DOI
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014 PubMed DOI
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024 PubMed DOI
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010 PubMed DOI
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010 PubMed DOI
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019 PubMed DOI
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016 PubMed DOI
View all evidence for Niacin →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.