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Zen Sleep with P5P and 5-HTP

product on market Capsule Allergy Research Group Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 75% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

L-5-HTP and GABA are supported by moderate evidence for promoting relaxation and improving sleep quality. Suntheanine and Vitamin B6 further assist in neurotransmitter synthesis and stress reduction. Overall, these ingredients have a well-documented profile for supporting sleep onset and maintenance.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Zen Sleep with P5P and 5-HTP
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Capsule(s)
Serving Size
30
Servings
Other Combinations
Product Type
75%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

10 mg (588% DV)
7.7× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
GABA
550 mg
200 mg
Market median: 200.0mg (358 products) 9 studies (A:0, B:2)
Market median: 100.0mg (116 products) 18 studies (A:0, B:3)

Other Ingredients

Hydroxypropyl Methylcellulose Microcrystalline Cellulose Rice Hull Concentrate Gum Arabic Sunflower Oil
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested use As a dietary supplement, 2 capsules 30 minutes before bedtime, or as directed by a healthcare practitioner.

Warnings & Precautions

Warning: Not indicated for pregnant or nursing women. If taking antidepressants or other psychotropic medications, use only under the supervision of a qualified healthcare practitioner.

Formulation Notes

Zen Sleep includes the same amounts of GABA and L-Theanine as the best-selling 200 mg of Zen, augmented with Vitamin B6 as P5P, and 5-HTP, the precursor to serotonin and melatonin.

This combination helps promote a relaxed state, and provides the necessary factors for the body to produce melatonin, supporting normal, healthy sleep.

Hypoallergenic

Additional Information

Keep in a cool, dry place, tightly capped.

Metadata

Product Details

UPC / SKU7 13947 77360 8
DSLD Entry Date2024-01-24
Product TypeOther Combinations
FormCapsule
DSLD ID304290
Data Updated2026-04-11
Research

Research Evidence

21
Research Sources
53
Avg Quality
11
Systematic Review
6
Rct
4
Meta Analysis
B Combination pharmacotherapy for the treatment of fibromyalgia in adults
Systematic Review The Cochrane database of systematic reviews 2018 PubMed DOI
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2001 PubMed
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2002 PubMed
B The impact of 5-hydroxytryptophan supplementation on sleep quality and gut microbiota composition in older adults: A randomized controlled trial
Rct Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
B The Impact of 5-Hydroxytryptophan Supplementation on Cognitive Function and Mood in Singapore Older Adults: A Randomized Controlled Trial
Rct Nutrients 2025 PubMed DOI
B The Efficacy of Different Triptans for the Treatment of Acute Headache in Pediatric Migraine: A Systematic Review
Systematic Review Indian pediatrics 2023 PubMed
B The effect of therapeutic massage combined with conventional therapy in children with functional dyspepsia: a systematic review and meta-analysis
Systematic Review Frontiers in pharmacology 2025 PubMed DOI
C Sleep disorders in children
Systematic Review BMJ clinical evidence 2010 PubMed
C Effects of 5-hydroxytryptophan on distinct types of depression: a systematic review and meta-analysis
Meta Analysis Nutrition reviews 2020 PubMed DOI
C Investigating genetic links between biological aging and adverse pregnancy outcomes
Meta Analysis Biogerontology 2025 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.