PhosphaLine by XYMOGEN — Ingredients, Evidence & Safety

🟢 100/100

This product looks safe

No ingredients exceed tolerable upper intake levels
33% of ingredients have research evidence

A Label Compliance Grade

Product Label

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Label Data

2 Softgel(s) Serving Size

33 Servings

Fat/Fatty Acid Product Type

33% Evidence Coverage

Supplement Facts — Evidence Check

Calories

30 Calorie(s)

Total Fat

3 Gram(s) (4% DV)

Polyenylphosphatidylcholine

2.7 Gram(s)

📊 Market median: 125.0mg (294 products) 📚 36 studies (Tier A: 1, B: 7)

RDA 550mg This product: 2.7mg UL 3500mg

Other Ingredients

Porcine Gelatin Glycerin Water Glycerides and Fatty Acids Medium Chain Triglyceride Oil Ethanol

Label Claims — Verification

❓ Nutrient

❓ All Other

❓ Structure/Function

All Other (97% of products) Structure/Function (90% of products) Nutrient (42% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free Dairy Free

Product Information

📋 Directions for Use

DIRECTIONS: Take two to three softgels daily, or as directed by your healthcare practitioner.

⚠️ Warnings & Precautions

Consult your healthcare practitioner prior to use.

Individuals taking medication should discuss potential interactions with their healthcare practitioner.

Do not use if tamper seal is damaged.

STORAGE: Keep tightly closed in a dry place at controlled room temperature 15-30 degrees C (59-86 degrees F), out of reach of children.

Contains: Soy.

🧪 Formulation Notes

PhosphaLine provides 2.7 g of pure polyenylphosphatidylcholine (PPC) per serving plus the highest concentrated source of 1,2 DLPC (dilinoleoylphosphatidylcholine). Unlike most other phosphatidylcholine products on the market, PhosphaLine contains no other phospholipids, aside from PPC and DLPC, that may compete for absorption. Studies suggest that PPC ingestion increases choline levels in the blood and brain and supports acetylcholine synthesis for healthy neuronal and cell function. Daily supplementation of PPC may help maintain healthy brain and liver function, healthy cholesterol levels already within the normal range, and gastric mucosal protection. PPC is widely used to support healthy aging.

DOES NOT CONTAIN: Wheat, gluten, yeast, dairy products, fish, shellfish, peanuts, tree nuts, egg, artificial colors, artificial sweeteners, or artificial preservatives.

100% Pure Polyenylphosphatidylcholine Concentrate

Additional Information

STORAGE: Keep tightly closed in a dry place at controlled room temperature 15-30 degrees C (59-86 degrees F), out of reach of children.

ePV (ePedigree Verification)

GMP compliant third-party verified

Scan to learn more! This package is completely recyclable

Servings per container: About 33

Product Details

UPC / SKU 8 71149 00103 2

DSLD Entry Date 2023-12-14

Product Type Fat/Fatty Acid

Form Softgel Capsule

Brand XYMOGEN

DSLD ID 303820

Data Updated 2026-04-11

Research Evidence

28 Research Sources

47 Avg Quality Score

11 Clinical Trial

8 Rct

2 Guideline

2 Meta Analysis

2 Regulatory Source

1 Systematic Review

1 Openfda Safety

B Greater Choline-Containing Compounds and Myo-inositol in Treatment-Resistant Versus Responsive Schizophrenia: A 1H-Magnetic Resonance Spectroscopy Meta-analysis

Meta Analysis Biological psychiatry. Cognitive neuroscience and neuroimaging 2024

PubMed DOI

B Integrating multi-structure covalent docking with machine-learning consensus scoring enhances potency ranking of human acetylcholinesterase inhibitors.

Guideline Briefings in bioinformatics 2026

PubMed DOI

B Evidence-based clinical practice guidelines for functional dyspepsia 2021.

Guideline Journal of gastroenterology 2022

PubMed DOI

B Scientific Opinion on health claims related to choline

Regulatory Source EFSA Journal 2011

DOI

C Effectiveness of nutritional interventions to prevent nonprogressive congenital and perinatal brain injuries: a systematic review and meta-analysis of randomized trials

Meta Analysis Nutrition reviews 2022

PubMed DOI

C Two methods for assessment of choline status in a randomized crossover study with varying dietary choline intake in people: isotope dilution MS of plasma and in vivo single-voxel magnetic resonance spectroscopy of liver.

Rct The American journal of clinical nutrition

PubMed DOI

C Choline and betaine concentrations in plasma discriminate levels of dietary choline intake in healthy adults: analysis of a double-blind randomized crossover controlled feeding study.

Rct The American journal of clinical nutrition

PubMed DOI

C Nutrient-based therapies for bipolar disorder: a systematic review

Systematic Review Psychotherapy and psychosomatics 2013

PubMed DOI

C The association of betaine, homocysteine and related metabolites with cognitive function in Dutch elderly people

Rct The British journal of nutrition 2007

PubMed

C Differential metabolism of choline supplements in adult volunteers.

Rct European journal of nutrition

PubMed DOI

View all evidence for Choline →