🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 43% of ingredients have research evidence
A Label Compliance Grade

Product Label

📸

Have a supplement label? Find it here.

Upload a photo of any supplement label to search our database of 92,312 products.

Label Data

3 Veggie Capsule(s) Serving Size
30 Servings
Other Combinations Product Type
43% Evidence Coverage

Supplement Facts — Evidence Check

52 mg (2% DV)
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 52mg
Sodium
30 mg (1% DV)
Potassium
55 mg (1% DV)
📊 Market median: 1000.0mg (1115 products) 📚 22 studies (Tier A: 0, B: 9)
This product: 450mg
📊 Market median: 600.0mg (79 products) 📚 24 studies (Tier A: 0, B: 6)
This product: 320mg
OptiMSM
300 mg
UC-II standardized Cartilage
40 mg

Other Ingredients

Hypromellose Microcrystalline Cellulose Magnesium Stearate Silicon Dioxide

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (100% of products) Structure/Function (89% of products) Nutrient (16% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

Suggested adult use: Take 3 capsules daily with food, or as recommended by a nutritionally informed physician.

⚠️ Warnings & Precautions

Contains shellfish (crab and shrimp shells)

Warning: Consult your physician before using any health supplement if pregnant, lactating, have a medical condition, or taking medications for diabetes, glaucoma or warfarin.

Not sure use by individuals under the age of 18 years. Keep out of reach of children.

🧪 Formulation Notes

GCM + UC-II is a unique combination of four joint support nutrients: glucosamine, chondroitin, MSM, and UC-II ingredient. A small amount, 40 mg of UC-II has been found to promote joint comfort permitting Doctor's Best to create a smaller, easier to swallow capsule, what we call a "maintenance" dose. Double-blind, placebo controlled clinical studies have shown that a daily dose of 40 mg of UC-II supplementation is both safe and effective in supporting joint comfort. UC-II is a Lonza trademark.

Non-GMO/Gluten free/Soy free

This product contains a natural ingredient that may vary in color.

Easy to swallow Maintenance dose

OptiMSM

Supports joint health

UC-II Undenatured type II collagen

Additional Information

Store in a cool dry place.

Science-based nutrition

Product Details

UPC / SKU 7 53950 00592 1
DSLD Entry Date 2023-12-14
Product Type Other Combinations
Form Capsule
DSLD ID 302664
Data Updated 2026-04-11

Research Evidence

39 Research Sources
50 Avg Quality Score
20 Rct
9 Meta Analysis
4 Clinical Trial
3 Systematic Review
1 Regulatory Source
1 Openfda Safety
B Interventions for the management of temporomandibular joint osteoarthritis
Systematic Review The Cochrane database of systematic reviews 2012
B Glucosamine therapy for treating osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2005
B Chondroitin for osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2015
B Efficacy and safety of the combination of glucosamine and chondroitin for knee osteoarthritis: a systematic review and meta-analysis
Meta Analysis Archives of orthopaedic and trauma surgery 2023
B Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis
Rct The New England journal of medicine 2006
B Oral Glucosamine in the Treatment of Temporomandibular Joint Osteoarthritis: A Systematic Review
Systematic Review International journal of molecular sciences 2023
B Scientific Opinion on glucosamine and joint health
Regulatory Source EFSA Journal 2009
B Clinical Efficacy and Safety of Chondroitin Combined with Glucosamine in the Treatment of Knee Osteoarthritis: A Systematic Review and Meta-Analysis
Meta Analysis Computational and mathematical methods in medicine 2022
B Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib
Rct Annals of the rheumatic diseases 2016
B Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trials
Meta Analysis Journal of orthopaedic surgery and research 2018
View all evidence for Glucosamine →

Compare Similar Products

View all Glucosamine products →