Home/ Supplements/ Glucosamine/ Glucosamine Chondroitin MSM + UCII

Glucosamine Chondroitin MSM + UCII

product on market Capsule Doctor's Best Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 43% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

Glucosamine and chondroitin sulfate are supported by moderate evidence for managing joint health and cartilage integrity. MSM and UC-II are often used to reduce inflammation and joint discomfort. Research on these combined ingredients generally indicates a favorable safety profile for most adults.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Glucosamine Chondroitin MSM + UCII
Open Full PDF View on NIH DSLD →
Details

Label Data

3 Veggie Capsule(s)
Serving Size
30
Servings
Other Combinations
Product Type
43%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

52 mg (2% DV)
Market median: 4002.0mg (1 products) 21 studies (A:0, B:2)
Sodium
30 mg (1% DV)
Potassium
55 mg (1% DV)
Market median: 1000.0mg (1115 products) 24 studies (A:0, B:9)
Market median: 600.0mg (79 products) 25 studies (A:0, B:6)
OptiMSM
300 mg
UC-II standardized Cartilage
40 mg

Other Ingredients

Hypromellose Microcrystalline Cellulose Magnesium Stearate Silicon Dioxide
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested adult use: Take 3 capsules daily with food, or as recommended by a nutritionally informed physician.

Warnings & Precautions

Contains shellfish (crab and shrimp shells)

Warning: Consult your physician before using any health supplement if pregnant, lactating, have a medical condition, or taking medications for diabetes, glaucoma or warfarin.

Not sure use by individuals under the age of 18 years. Keep out of reach of children.

Formulation Notes

GCM + UC-II is a unique combination of four joint support nutrients: glucosamine, chondroitin, MSM, and UC-II ingredient. A small amount, 40 mg of UC-II has been found to promote joint comfort permitting Doctor's Best to create a smaller, easier to swallow capsule, what we call a "maintenance" dose. Double-blind, placebo controlled clinical studies have shown that a daily dose of 40 mg of UC-II supplementation is both safe and effective in supporting joint comfort. UC-II is a Lonza trademark.

Non-GMO/Gluten free/Soy free

This product contains a natural ingredient that may vary in color.

Easy to swallow Maintenance dose

OptiMSM

Supports joint health

UC-II Undenatured type II collagen

Additional Information

Store in a cool dry place.

Science-based nutrition

Metadata

Product Details

UPC / SKU7 53950 00592 1
DSLD Entry Date2023-12-14
Product TypeOther Combinations
FormCapsule
BrandDoctor's Best
DSLD ID302664
Data Updated2026-04-11
Research

Research Evidence

39
Research Sources
50
Avg Quality
20
Rct
9
Meta Analysis
4
Clinical Trial
3
Systematic Review
1
Regulatory Source
1
Openfda Safety
B Interventions for the management of temporomandibular joint osteoarthritis
Systematic Review The Cochrane database of systematic reviews 2012 PubMed DOI
B Glucosamine therapy for treating osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2005 PubMed
B Chondroitin for osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
B Efficacy and safety of the combination of glucosamine and chondroitin for knee osteoarthritis: a systematic review and meta-analysis
Meta Analysis Archives of orthopaedic and trauma surgery 2023 PubMed DOI
B Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis
Rct The New England journal of medicine 2006 PubMed
B Oral Glucosamine in the Treatment of Temporomandibular Joint Osteoarthritis: A Systematic Review
Systematic Review International journal of molecular sciences 2023 PubMed DOI
B Scientific Opinion on glucosamine and joint health
Regulatory Source EFSA Journal 2009 DOI
B Clinical Efficacy and Safety of Chondroitin Combined with Glucosamine in the Treatment of Knee Osteoarthritis: A Systematic Review and Meta-Analysis
Meta Analysis Computational and mathematical methods in medicine 2022 PubMed DOI
B Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib
Rct Annals of the rheumatic diseases 2016 PubMed DOI
B Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trials
Meta Analysis Journal of orthopaedic surgery and research 2018 PubMed DOI
View all evidence for Glucosamine →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.