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Niacinamide 1000 mg

product on market Tablet or Pill NaturesPlus Safety: 60/100
60/100

Review before taking

  • Niacin: 1000mg is 28.6× the Tolerable Upper Intake Level (35mg)
  • 100% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Niacin supports cellular energy production and lipid metabolism, with strong evidence for its role in managing certain cholesterol levels. However, a safety score of 60 suggests potential concerns, such as the risk of flushing or liver enzyme elevations at high doses. Users should be aware of these possible adverse reactions.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 1000mg is 28.6× the Tolerable Upper Intake Level (35mg)

AI-generated · Qwen 3.6 · grounded in 2 sources · methodology

This product received a low safety score because the amount of Niacin is nearly 29 times higher than the recommended upper limit for daily intake.

Label

Product Label

Label for Niacinamide 1000 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Tablet(s)
Serving Size
90
Servings
Vitamin
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

1000 mg NE (6250% DV)
Exceeds UL by 28.6× (UL: 35 mg) 196 studies (A:5, B:63)

Other Ingredients

Stearic Acid Dicalcium Phosphate Hydroxypropyl Methylcellulose Magnesium Stearate Rice Bran Silica Pharmaceutical Glaze
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: One tablet daily.

Warnings & Precautions

Keep out of reach of children.

Formulation Notes

Niacinamide is the "non-flush" version of the nutrient Niacin (vitamin B3). It is key in hundreds of metabolic reactions. Every process in every cell of the human body relies on the energy-producing reactions of Niacin. It is used by the body or the synthesis of proteins and fatty acids as well as the formation of hormones and red blood cells. Most importantly, Niacin is an important regulator of white blood cells, needed for a strong immune response.

In special base which provides for the gradual release of ingredients over a prolonged period of time. Micro-gel sustained release system

Sustained release Heart Support

Intended for the correction of Niacin deficiency.

Vegetarian

Gluten Free

Free from artificial colors and artificial preservatives. Free from all the major allergens identified in the U.S. Food Allergen Labeling and Consumer Protection Act.

Additional Information

Keep tightly closed in a cool, dry place.

Metadata

Product Details

UPC / SKU0 97467 01930 0
DSLD Entry Date2023-10-24
Product TypeVitamin
FormTablet or Pill
DSLD ID298729
Data Updated2026-04-11
Research

Research Evidence

241
Research Sources
55
Avg Quality
113
Meta Analysis
75
Systematic Review
32
Rct
11
Clinical Trial
3
Other
3
Regulatory Source
1
Cochrane Review
1
Narrative Review
1
Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013 PubMed DOI
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014 PubMed DOI
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024 PubMed DOI
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010 PubMed DOI
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010 PubMed DOI
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019 PubMed DOI
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016 PubMed DOI
View all evidence for Niacin →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.