🟢 90/100

This product looks safe

  • Manganese: 20mg is 1.8× the Tolerable Upper Intake Level (11mg)
  • 50% of ingredients have research evidence
C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Manganese: 20mg is 1.8× the Tolerable Upper Intake Level (11mg)

Label Data

2 Extended Delivery Tablet(s) Serving Size
30 Servings
Other Combinations Product Type
50% Evidence Coverage

Supplement Facts — Evidence Check

Vitamin C
200 mg (333% DV)
20 mg (100% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 1.8× (UL: 11 mg) 📚 8 studies — no high-quality reviews
RDA 2.3mg This product: 20mg UL 11mg
📊 Market median: 1000.0mg (1115 products) 📚 22 studies (Tier A: 0, B: 9)
This product: 1000mg
📊 Market median: 600.0mg (79 products) 📚 24 studies (Tier A: 0, B: 6)
This product: 1000mg

Other Ingredients

Hydroxypropyl Methylcellulose Cellulose Magnesium Stearate Stearic Acid Silica Pharmaceutical Glaze

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (100% of products) Structure/Function (89% of products) Nutrient (16% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free Dairy Free

Product Information

📋 Directions for Use

Directions: As a dietary supplement, two tablets once daily.

⚠️ Warnings & Precautions

Contains crustacean shellfish.

Keep out of reach of children.

This is not a prescription product. It is a dietary supplement made with the highest possible quality standards.

🧪 Formulation Notes

Nutritional support for healthy joint function. Rx-Joint is a targeted, condition-specific formulation designed to nutritionally support healthy joint function.

Each mega-potency serving supplies 1000 mg each of pure glucosamine sulfate and chondroitin sulfate, the preferred forms of these critical nutrients. This powerful complex is then fused with a unique profile of essential cofactors, including buffered vitamin C and manganese glycinate, for peak efficiency.

Rx-Joint, formulated with a proprietary extended-delivery system, allows natural, gradual absorption for maximum nutritional support.

Free from artificial colors and preservatives. Free from the allergens milk, eggs, fish, tree nuts, peanuts, wheat and soybeans.

Gluten free

Nutritional Supplement with essential cofactors

In a special base which provides for the gradual release of ingredients over a prolonged period of time.

Additional Information

Keep tightly closed in a cool, dry place.

Product Details

UPC / SKU 0 97467 04920 8
DSLD Entry Date 2023-10-24
Product Type Other Combinations
Form Tablet or Pill
Brand NaturesPlus
DSLD ID 298224
Data Updated 2026-04-11

Research Evidence

39 Research Sources
50 Avg Quality Score
20 Rct
9 Meta Analysis
4 Clinical Trial
3 Systematic Review
1 Regulatory Source
1 Openfda Safety
B Interventions for the management of temporomandibular joint osteoarthritis
Systematic Review The Cochrane database of systematic reviews 2012
B Glucosamine therapy for treating osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2005
B Chondroitin for osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2015
B Efficacy and safety of the combination of glucosamine and chondroitin for knee osteoarthritis: a systematic review and meta-analysis
Meta Analysis Archives of orthopaedic and trauma surgery 2023
B Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis
Rct The New England journal of medicine 2006
B Oral Glucosamine in the Treatment of Temporomandibular Joint Osteoarthritis: A Systematic Review
Systematic Review International journal of molecular sciences 2023
B Scientific Opinion on glucosamine and joint health
Regulatory Source EFSA Journal 2009
B Clinical Efficacy and Safety of Chondroitin Combined with Glucosamine in the Treatment of Knee Osteoarthritis: A Systematic Review and Meta-Analysis
Meta Analysis Computational and mathematical methods in medicine 2022
B Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib
Rct Annals of the rheumatic diseases 2016
B Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trials
Meta Analysis Journal of orthopaedic surgery and research 2018
View all evidence for Glucosamine →

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