🟢 92/100

This product looks safe

  • Manganese: 20mg is 1.8× the Tolerable Upper Intake Level (11mg)
  • 40% of ingredients have research evidence
C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Manganese: 20mg is 1.8× the Tolerable Upper Intake Level (11mg)

Label Data

3 Extended Delivery Tablet(s) Serving Size
30 Servings
Other Combinations Product Type
40% Evidence Coverage

Supplement Facts — Evidence Check

Vitamin C
200 mg (222% DV)
20 mg (870% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 1.8× (UL: 11 mg) 📚 8 studies — no high-quality reviews
RDA 2.3mg This product: 20mg UL 11mg
📊 Market median: 1000.0mg (1115 products) 📚 22 studies (Tier A: 0, B: 9)
This product: 1000mg
📊 Market median: 1000.0mg (2 products)
This product: 1000mg
📊 Market median: 600.0mg (79 products) 📚 24 studies (Tier A: 0, B: 6)
This product: 800mg

Other Ingredients

Hydroxypropyl Methylcellulose Stearic Acid Dicalcium Phosphate Magnesium Stearate Pharmaceutical Glaze

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (100% of products) Structure/Function (89% of products) Nutrient (16% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free Dairy Free

Product Information

📋 Directions for Use

Directions: As a dietary supplement, three tablets once daily.

⚠️ Warnings & Precautions

Keep out of reach of children.

This is not a prescription product. It is a dietary supplement made with the highest possible quality standards.

🧪 Formulation Notes

Nutritional Support for Healthy Joint Function Advanced Therapeutics Glucosamine Chondroitin MSM Ultra Rx-Joint is a targeted, condition-specific formulation designed to nutritionally support healthy joint function. Each triple-action tablet supplies the critical joint nutrients - glucosamine sulfate, chondroitin sulfate and methylsufonylmethane (MSM) - for peak joint lubrication and mobility.

Free from artificial colors and artificial preservatives. Free from the allergens milk, eggs, fish, tree nuts, peanuts, wheat and soy.

In a special base which provides for the gradual release of ingredients over a prolonged period of time.

Gluten Free

Triple Action MSM Opti MSM Optimal Purity Optimal Health

Additional Information

Keep tightly closed in a cool, dry place.

Product Details

UPC / SKU 0 97467 04923 9
DSLD Entry Date 2023-10-24
Product Type Other Combinations
Form Tablet or Pill
Brand NaturesPlus
DSLD ID 298221
Data Updated 2026-04-11

Research Evidence

39 Research Sources
50 Avg Quality Score
20 Rct
9 Meta Analysis
4 Clinical Trial
3 Systematic Review
1 Regulatory Source
1 Openfda Safety
B Interventions for the management of temporomandibular joint osteoarthritis
Systematic Review The Cochrane database of systematic reviews 2012
B Glucosamine therapy for treating osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2005
B Chondroitin for osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2015
B Efficacy and safety of the combination of glucosamine and chondroitin for knee osteoarthritis: a systematic review and meta-analysis
Meta Analysis Archives of orthopaedic and trauma surgery 2023
B Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis
Rct The New England journal of medicine 2006
B Oral Glucosamine in the Treatment of Temporomandibular Joint Osteoarthritis: A Systematic Review
Systematic Review International journal of molecular sciences 2023
B Scientific Opinion on glucosamine and joint health
Regulatory Source EFSA Journal 2009
B Clinical Efficacy and Safety of Chondroitin Combined with Glucosamine in the Treatment of Knee Osteoarthritis: A Systematic Review and Meta-Analysis
Meta Analysis Computational and mathematical methods in medicine 2022
B Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib
Rct Annals of the rheumatic diseases 2016
B Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trials
Meta Analysis Journal of orthopaedic surgery and research 2018
View all evidence for Glucosamine →

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