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Berberine

product on market Capsule Enzymedica Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 50% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Berberine hydrochloride has strong evidence for supporting healthy blood glucose levels and metabolic function. Leucine is a branched-chain amino acid primarily used to support muscle protein synthesis. Overall, the evidence coverage for this specific formulation is very limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Berberine
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
120
Servings
Other Combinations
Product Type
50%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Market median: 500.0mg (234 products) 95 studies (A:0, B:35)
50 mg
Market median: 17.4mg (161 products)

Other Ingredients

Cellulose Gellan Gum Water Rice concentrate Calcium Laurate
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Recommended Use: 1 capsule with meals, three times a day.

Warnings & Precautions

Consult with physician prior to use if you are pregnant or nursing, taking medications or have a medical condition.

1 Caution: This product is not intended for individuals with impaired glucose metabolism such as prediabetes or diabetes. Do not use if safety seal is broken or missing.

Please keep out of reach of children

Formulation Notes

Berberine from Barberry

For Blood Sugar Metabolism 1,2 Cardiovascular, immune and metabolic support Eco-Friendly - naturally sustainable source

Non GMO Certified by NSF

Vegan Dietary Supplement

Ultimate Results Targeted-Delivery Capsules Plant-based, acid resistant capsules help protect the berberine from stomach acid to deliver optimal results without the need for artificial coatings or additives. Balanced Blood Sugar 2 Berberine supports and maintains blood sugar levels already within a normal range. Supercharged Metabolism Berberine has been shown to influence the enzyme AMPK, which is involved in regulating the body's energy levels and other metabolic processes. Happy Heart & Body Berberine promotes healthy blood cholesterol levels, already within a normal range.

Plant-based, acid resistant capsules help protect the berberine from stomach acid to deliver optimal results without the need for artificial coatings or additives.

Contains NO: Gluten, milk, casein, soy, egg, artificial colors or flavors

Made in USA with global ingredients

Enzymedica's Berberine is standardized for maximum potency and is sustainably sourced from Barberry.

Benefits of Berberine Use in traditional medicine for centuries, Berberine is renowned as a safe and effective herbal remedy for supporting both blood sugar and cholesterol levels already within a normal range, healthy metabolism and microbiome balance. Our berberine is 100% derived from the Barberry plant, which grows abundantly, is naturally sustainable and rich in valuable phytochemicals. Quality - Standardized Enzymedica's berberine is standardized to 95%. This means you are getting a consistent, potent dose of active berberine; the most beneficial compound in the barberry plant. Our berberine is tested for quality and purity both before and after manufacturing. Other products that are not standardized cannot guarantee purity and consistency.

Additional Information

Non GMO Certified by NSF

Keep closed in dry place; avoid excessive heat.

30 Day Money Back Guarantee Enzymedica Supports Vitamin Angels Proud Supporter Green Mountain Energy

Importance of Source Berberine can be sourced from many plants, including Barberry and Goldenseal. Unfortunately, Goldenseal is an "at risk" plant due to overharvesting in the wild and its use is strongly discouraged by plant conservationists. United Plant Savers Medicinal Plant Conservation

Autism Hope Alliance AHA

Metadata

Product Details

UPC / SKU6 70480 10085 1
DSLD Entry Date2023-09-25
Product TypeOther Combinations
FormCapsule
DSLD ID296456
Data Updated2026-04-11
Research

Research Evidence

98
Research Sources
55
Avg Quality
48
Systematic Review
39
Meta Analysis
4
Rct
4
Clinical Trial
1
Other
1
Narrative Review
1
Openfda Safety
B Efficacy and safety of berberine for dyslipidaemias: A systematic review and meta-analysis of randomized clinical trials
Meta Analysis Phytomedicine : international journal of phytotherapy and phytopharmacology 2018 PubMed DOI
B Effects berberine-silymarin on liver enzymes: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition ESPEN 2022 PubMed DOI
B Efficacy and safety of berberine for several cardiovascular diseases: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 PubMed DOI
B Effect of Berberine on C-reactive protein: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2019 PubMed DOI
B Overall and Sex-Specific Effect of Berberine on Glycemic and Insulin-Related Traits: a Systematic Review and Meta-Analysis of Randomized Controlled Trials
Meta Analysis The Journal of nutrition 2023 PubMed DOI
B The clinical efficacy and safety of berberine in the treatment of non-alcoholic fatty liver disease: a meta-analysis and systematic review
Meta Analysis Journal of translational medicine 2024 PubMed DOI
B Berberine Effects in Pre-Fibrotic Stages of Non-Alcoholic Fatty Liver Disease-Clinical and Pre-Clinical Overview and Systematic Review of the Literature
Systematic Review International journal of molecular sciences 2024 PubMed DOI
B Efficacy and Safety of Berberine Alone or Combined with Statins for the Treatment of Hyperlipidemia: A Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials
Meta Analysis The American journal of Chinese medicine 2019 PubMed DOI
B Effects of Berries, Phytochemicals, and Probiotics on Atherosclerosis through Gut Microbiota Modification: A Meta-Analysis of Animal Studies
Meta Analysis International journal of molecular sciences 2023 PubMed DOI
B Berberine Ursodeoxycholate for the Treatment of Type 2 Diabetes: A Randomized Clinical Trial
Rct JAMA network open 2025 PubMed DOI
View all evidence for Berberine →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.