Arginine Plus

product on market Tablet or Pill Metagenics 🟢 Safety: 90/100
Brand: Metagenics
🟢 90/100

This product looks safe

  • Folate: 665mg is 665.0× the Tolerable Upper Intake Level (1.0mg)
  • 25% of ingredients have research evidence
C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Folate: 665mg is 665.0× the Tolerable Upper Intake Level (1.0mg)

Label Data

2 Tablet(s) Serving Size
60 Servings
Fiber and Other Nutrients Product Type
25% Evidence Coverage

Supplement Facts — Evidence Check

Total Carbohydrates
1 Gram(s) (1% DV)
665 mcg DFE (166% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 665.0× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 665mg UL 1.0mg
1.5 Gram(s)
📊 Market median: 500.0mg (143 products)
This product: 1.5mg
Glycine
10 mg

Other Ingredients

Microcrystalline Cellulose Cellulose Stearic Acid Silica Calcium Silicate Croscarmellose Sodium Hypromellose Medium Chain Triglyceride Hydroxypropyl Cellulose

Label Claims — Verification

❓ Nutrient
❓ All Other
❓ Structure/Function
All Other (100% of products) Structure/Function (91% of products) Nutrient (35% of products)

Target Groups

Vegetarian Adult (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

Directions: Take two tablets two times daily or as directed by your healthcare practitioner.

⚠️ Warnings & Precautions

Caution: If pregnant or nursing, or taking medications, consult your healthcare practitioner before use.

If you have had a myocardial infarction (heart attack) or have a history of renal (kidney) impairment, consult your cardiologist or physician before use.

Keep out of the reach of children.

Practitioner exclusive

🧪 Formulation Notes

Arginine Plus delivers high quality L-arginine with calcium L-5-methyltetrahydrofolate to support healthy blood flow, homocysteine levels, and overall cardiovascular health. Providing L-5-methyltetrahydrofolate helps to ensure improved folate nutrition, even in those with genetic variations in folate metabolism.

This product is non GMO, gluten free, and vegetarian.

This product is non GMO, gluten free, and vegetarian.

Support for healthy cardiovascular function

Additional Information

Storage: Keep tightly closed in a cool, dry place. Do not refrigerate.

Certified Gluten Free GFCO.org

Product Details

UPC / SKU 7 55571 91055 4
DSLD Entry Date 2023-08-23
Product Type Fiber and Other Nutrients
Form Tablet or Pill
Brand Metagenics
DSLD ID 295630
Data Updated 2026-04-11

Research Evidence

45 Research Sources
52 Avg Quality Score
12 Rct
11 Systematic Review
11 Meta Analysis
11 Clinical Trial
A Nitric oxide donors (nitrates), L-arginine, or nitric oxide synthase inhibitors for acute stroke
Meta Analysis The Cochrane database of systematic reviews 2017
PubMed DOI Cochrane
A Arginine supplementation for prevention of necrotising enterocolitis in preterm infants
Meta Analysis The Cochrane database of systematic reviews 2017
PubMed DOI Cochrane
B Nutritional interventions for treating foot ulcers in people with diabetes
Meta Analysis The Cochrane database of systematic reviews 2020
PubMed DOI
B Nitric oxide donors (nitrates), L-arginine, or nitric oxide synthase inhibitors for acute stroke
Systematic Review The Cochrane database of systematic reviews 2002
PubMed Cochrane
B Arginine supplementation for prevention of necrotising enterocolitis in preterm infants
Systematic Review The Cochrane database of systematic reviews 2007
PubMed Cochrane
B The Effect of Amino Acids on Wound Healing: A Systematic Review and Meta-Analysis on Arginine and Glutamine
Meta Analysis Nutrients 2021
PubMed DOI
B Nitric oxide donors (nitrates), L-arginine, or nitric oxide synthase inhibitors for acute ischaemic stroke
Systematic Review The Cochrane database of systematic reviews 2000
PubMed Cochrane
B Dietary Supplements for Erectile Dysfunction: Analysis of Marketed Products, Systematic Review, Meta-Analysis and Rational Use
Meta Analysis Nutrients 2023
PubMed DOI
B Arginine supplementation for prevention of necrotising enterocolitis in preterm infants
Systematic Review The Cochrane database of systematic reviews 2004
PubMed Cochrane
B An Analysis of Popular Online Erectile Dysfunction Supplements
Systematic Review The journal of sexual medicine 2019
PubMed DOI
View all evidence for L Arginine →

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