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M.S.M. Benefits

product on market Capsule ProCaps Laboratories Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 33% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

MSM and Type II Collagen are associated with joint support, while Vitamin C is essential for collagen synthesis. Research evidence for these ingredients varies from moderate to limited in efficacy for joint health. The profile maintains a high safety score with no significant concerns noted.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for M.S.M. Benefits
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
360
Servings
Other Combinations
Product Type
33%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Vitamin C
100 mg (167% DV)
MSM
400 mg
Market median: 1000.0mg (2 products)
Market median: 20.0mg (931 products) 234 studies (A:1, B:90)

Other Ingredients

Gelatin Capsule
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

SUGGESTED USE For the healthy support of your joints, consume one or more capsules daily or as recommended by a health care professional. Many individuals seek to consume 800 to 2,000 mg daily of M.S.M. (Methylsulfonylmethane), which is the amount contained in 2 to 5 capsules. For best results take M.S.M. Benefits with food, preferably a complete meal.

Formulation Notes

400 mg Methylsulfonylmethane Type II Collagen

CONTAINS NO Milk, soy, yeast, corn, wheat, gluten, sodium, salt, sugar, fat, cholesterol, color, preservative or manufacturing additive. CONTAINS NO ADDITIVES OR COMMON ALLERGENS OF ANY KIND.

Additional Information

This product is most effective as part of a healthy diet and active lifestyle, along with one of Andrew Lessman’s multi-vitamin-mineral formulas. For answers to questions about the use of this product call 800.800.1200.

All-Solar MANUFACTURING

600367 - 02P

Andrew Lessman’s M.S.M. Benefits delivers a concentrated source of a vital, but often overlooked dietary component – Sulfur. The initials M.S.M. stand for Methylsulfonylmethane, which is a simple organic molecule that is built around the sulfur atom that it readily donates. Sulfur is important to your body because it is a vital structural component in the connective tissues that comprise all our joints, as well as the tissues of our hair, skin and nails. In fact, it is sulfur’s unique ability to create disulfide linkages that allows tissues like our joints and skin to retain their structural integrity, along with their youthful, desirable elastic properties. In short, sulfur is required to maintain the healthy structure and function of the connective tissue (cartilage, ligaments and tendons) in all our joints, while it is also required as a structural component of the tissues and proteins (elastin, keratin and collagen) of our hair, skin and nails. Sulfur is an essential building block and vital structural ingredient that is necessary to support, maintain and fortify healthy cartilage and connective tissue throughout your body, but until recently has gone relatively overlooked. M.S.M. Benefits delivers a convenient source of this important element and also provides Vitamin C and Type II Collagen to help support M.S.M.’s role in the maintenance of healthy joint structure and function.

Metadata

Product Details

DSLD Entry Date2014-01-24
Product TypeOther Combinations
FormCapsule
DSLD ID29398
Data Updated2026-04-11
Research

Research Evidence

371
Research Sources
54
Avg Quality
148
Meta Analysis
82
Systematic Review
71
Rct
62
Clinical Trial
2
Regulatory Source
1
Cochrane Review
1
Narrative Review
1
Other
1
Openfda Safety
A Vitamin C supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin C supplementation for the primary prevention of cardiovascular disease
Systematic Review The Cochrane database of systematic reviews 2017 PubMed DOI
A Vitamin C for preventing and treating the common cold
Meta Analysis The Cochrane database of systematic reviews 2013 PubMed DOI
A Vitamin C for preventing and treating pneumonia
Meta Analysis The Cochrane database of systematic reviews 2013 PubMed DOI
A Vitamin E supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin C supplementation for prevention and treatment of pneumonia
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Vitamin C supplementation for prevention and treatment of pneumonia
Systematic Review The Cochrane database of systematic reviews 2021 PubMed DOI
A Nutritional interventions for preventing and treating pressure ulcers
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
A Does Vitamin C Supplementation Provide a Protective Effect in Periodontal Health? A Systematic Review and Meta-Analysis
Meta Analysis International journal of molecular sciences 2024 PubMed DOI
A Circulating vitamin C concentration and risk of cancers: a Mendelian randomization study
Meta Analysis BMC medicine 2021 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.